Smith & Nephew to Buy Osiris Therapeutics

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Smith & Nephew plc (LSE:SN, NYSE:SNN), a $4.9b maker of orthopedic, wound management, sports medicine and trauma & extremities products, is acquiring Osiris Therapeutics, Inc., a provider of regenerative medicine products, including skin, bone graft and articular cartilage substitutes. The deal accelerates S&N’s wound management business. Osiris’ products include Grafix and Stravix for treating chronic wounds of diabetic foot ulcers, …

Medtronic to Acquire EPIX Therapeutics

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Medtronic plc (NYSE: MDT), a $29.95b manufacturer of cardio-vascular, orthopedic, spinal and other medical devices., is buying EPIX Therapeutics, Inc. (formerly Advanced Cardiac Therapeutics), a maker of a catheter-based, temperature-controlled cardiac ablation systems. The acquisition expands Medtronic’s cardiac ablation portfolio. EPIX manufactures a duct-based temperature system for controlling cardiac ablation for arrhythmia (arrhythmia), including atrial fibrillation. Its DiamondTemp ablation system, …

Abbott Laboratories to Acquire Cephea Valve Technologies

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Abbott Laboratories, a $20.4b global developer of diagnostics, medical devices, nutritionals and branded generic pharmaceuticals is buying Cephea Valve Technologies, Inc, a developer of a less-invasive heart valve replacement technology for mitral valve disease. The deal Strengthens Abbott’s in structural heart therapies. Cephea’s artificial valve is designed to be delivered through a vein in the leg, forgoing the need for open-heart surgery. Replacement of …

Bristol-Myers Squibb Buying Celgene for $74b

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Bristol-Myers Squibb Company, a $20.8b global biopharma company is buying Celgene Corporation, a $13b developer of therapies for cancer and inflammatory diseases. The Deal strengthens Bristol-Myers in oncology, cardiovascular disease, immunology and inflammation. Celgene is known for its blockbuster Thalomid and Revlimid cancer drugs. The combined company will have nine products with more than $1b in annual sales. In addition to the approved …

GlaxoSmithKline to Acquire Tesaro for $5.1b

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GlaxoSmithKline plc (GSK), a large European-based pharmaceutical manufacturer is acquiring TESARO Inc., an oncology-focused biopharmaceutical company. The transaction accelerates GSK’s commercial capability in oncology. TESARO’s major marketed product is Zejula (niraparib), an oral, once-daily ribose polymerase (PARP) inhibitor approved for use in ovarian cancer. It works by blocking an enzyme that cancer cells use to repair damage in their DNA. In Q3 2018, …

Colfax to Acquire DJO Global for $3.15b

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Colfax Corporation, a $3.6b diversified maker of fluid handling and other engineered products is acquiring DJO Global Inc, a leading maker of orthopedic bracing and other non-invasive rehab devcies. The deal diversifies CFX’ revenue streams and end-market exposure, reduces cyclicality, weights healthcare and creates a new growth platform for CFX. DJO’s primary offerings are: Aircast, DonJoy, and ProCare. It partners with …

With $1.6B Mazor Robotics Buy, Medtronic Spine is All-in

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Medtronic Plc (NYSE:MDT), agreed to buy Mazor Robotics Ltd. (NASDAQ:MZOR), a maker of robotic guidance systems, for $1.64bto strengthen its position in spine surgery. Medtronic’s spine division had been hit off-stride after the problems encountered with Kyphon purchase in 2007. Sales force flux, off-label use of a controversial biologics product, a DOJ investigation and nimble competitors chipping away have challenged …

CVS-Aetna Merger Accelerates Healthcare’s Transformation

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The Justice Department recently approved CVS’s mega $69b purchase of Aetna, conditioned on Aetna’s sell-off of its private Medicare drug plans. In addition to owning almost 10,000 retail stores in the U.S., CVS provides drug plans to more than 90 million people. It plans to use its pharmacy locations to provide consumers with more local care options, repurposing portions of …

CIGNA Corporation To Acquire Express Scripts

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CIGNA Corporation, a $41.62b provider of healthcar insurance services acquires Express Scripts Inc, a $100.06b provider of pharmacy benefit management services. The U.S. Justice Department recently cleared this deal, part of the wave of consolidations transforming the health care industry. Amazon’s move into the health care business has forced established companies to rethink how they can compete. Cigna and Express Scripts said their …

Stryker Corporation Acquires Invuity, Inc. For $190m

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Stryker Corporation, a $12.44b maker of Orthopedics, MedSurg, Neurotechnology and Spine products is acquiring Invuity, Inc, a manufacturer of photonics and single-use, lighted retractor instruments for open surgery. Invuity’s retractor-based lights provides direct visualization of surgical cavities during open minimally invasive and minimal access procedures. Invuity’s topline has grown by more than 20% last year, with gross margins in the high 60% to …