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Dynamic Healthcare M&A Database - 4Q09



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Acquiring Party    Onyx Pharmaceuticals, Inc. (ONXX), a biopharmaceutical company focused on cancer.
Transferring Party    Proteolix, Inc., a biopharmaceutical company targeting the proteasome for the treatment of hematological malignancies and solid tumors.
Sector    Biopharmaceuticals
Date    October 12, 2009
Analysis
Proteolix's lead compound, carfilzomib, is a proteasome inhibitor currently in multiple myeloma clinical trials. It is pioneering a new class of potent proteasome inhibitors, offering an important new therapy in oncology. Multiple myeloma is the second most common hematologic cancer and results from an abnormality of plasma cells, usually in the bone marrow. There have been limited treatment options. Deal value -- $276m plus up to $575m in milestone payments.




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