195 Medical Devices Johnson & Johnson (JNJ) a global manufacturer medical devices and consumer healthcare products. Guidant Corporation (GDT) a manufacturer of implantable defibrillators, pacemakers, stents and other cardiac products. See the January, 2005 Report: "Deal in the Spotlight". Transaction value about $24 billion, 40% cash, 60% stock. 2004-12-16T00:00:00 0 24000 724 Biopharmaceuticals Bayer AG a global pharmaceutical, diagnostics and industrial products manufacturer, based in Germany. Schering AG a large biopharmaceutical manufacturer, contraceptives and genetic technologies. The white-knight offer (countering German Merck KGaA's bid) grows Bayer's pharmaceutical specialty product business (its primary growth engine), adds an innovative product portfolio and a well-stocked pipeline. Deal value $19.5 billion, with prospective cost savings of more than $840m. Schering's sales and EBITDA were about $6.39b (3x) and $1.5b (13x). Subject to closing conditions. 2006-03-23T00:00:00 0 19500 6390 1500 622 Medical Services UnitedHealth Group a large diversifed managed care organization. PacificCare Health Systems a large health organizations, offering consumers health care and life insurance products. Combines and leverages the resources of two complementary businesses in the western United States, as well as nationally. Transaction price -- $9.2 billion. 2005-12-21T00:00:00 0 9200 616 Biopharmaceuticals Novartis AG (NVS) a developer and manufacturer of pharmaceuticals and nutritional products. Chiron Corporation (NASDAQ:CHIR) a leading biotechnology company. Novartis will acquire approximately the remaining 58% of Chiron shares it doesn't already own, for approx. $5.4 billion cash. Chiron's global vaccines business provides Novartis with entry into the vaccine segment; its blood testing business adds a high-value profit driver to Novartis and may offer a potential platform for future developments in molecular diagnostics 2005-11-11T00:00:00 0 5400 768 Biopharmaceuticals Abbott Laboratories (NYSE: ABT) a global, broad-based health care company devoted to the discovery, development, manufacture and marketing of pharmaceuticals and medical products, including nutritionals, devices and diagnostics. the vascular intervention and endovascular solutions business units of Guidant (NYSE: GDT) a developer and manufacturer of cardiovascular medical products. Guidant's vascular business offers a broad line of leading coronary and endovascular products, a pre-eminent sales force, and global manufacturing operations, as well as a state-of-the-art R&D organization, which is developing innovative technologies and devices such as the XIENCE(TM) V and ZoMaxx(TM) drug-eluting stents. Deal Price was $4.1b in cash for Guidant's vascular business. In addition, Abbott will pay Boston Scientific milestone payments of $250m at U.S. FDA approval of Guidant's drug-eluting stent, and an additional payment of $250m upon a similar approval in Japan. Abbott also provided Boston Scientific with a five-year, $900m interest-bearing loan. Abbott has purchased approximately 64m shares of Boston Scientific stock for $1.4 b which represents less than 5 percent of the company. 2006-04-24T00:00:00 1 4100 0 0 0 270 Medical Services Fresenius Medical Care AG (Germany) a leading provider of dialysis products and services. Renal Care Group, Inc. a dialysis service provider. The $3.5 billion acquisition solidifies Fresenius' as the leader in dialysis services in the US and provides an excellent strategic and geographic fit. Also leverages the Fresenius infrastructure. In 2004, Renal Care Group's revenue was approx. US$1.35billion with an EBIT of US$254 million. Asof March 31, 2005, Renal Care Group owned more than 425 dialysis clinics andserved over 30,400 patients. 2005-03-31T00:00:00 0 3500 1350 254 624 Medical Devices Allergan, Inc. a speciality pharmaceutical company focused on ophthalmology, neurosciences, medical dermatology, medical aesthetics and other specialty markets. Inamed Corporation a manufacturer of breast implants, dermal products to treat facial wrinkles, and minimally invasive devices for obesity intervention, including the LAP-BAND® System for morbid obesity. In this $3.4 billion proposal (countering a lower one by Medici Pharmaceutical Corp.) Allergan (maker of BOTOX) seeks to broaden its portfolio of medical aesthetic products and leverage significant growth and cross-marketing and cross-selling opportunities. 2006-03-23T00:00:00 0 3400 0 269 Medical Services DaVita Inc. (DVA) a provider of dialysis services for patients suffering from chronic kidney failure. Gambro AB (Stockholm:GAMBb.ST) a provider of hemodialysis, peritoneal dialysis and acute care to patients with renal disease. This acquisition of Gambro's U.S. dialysis clinics nearly doubles DaVita’s facilities in the U.S., adding 595 dialysis sites to its existing network of 611 clinics. After the transaction Gambro becomes the company's preferred supplier of dialysis equipment for a period of ten years. Transaction amount about $3.0 billion. 2004-12-07T00:00:00 0 3000 738 Biopharmaceuticals Amgen (NASDAQ: AMGN ) a biotechnology company that manufactures innovative human therapeutics. Abgenix, Inc. a company specializing in the discovery, development and manufacture of human therapeutic antibodies. Underscores Amgen's commitment to therapeutic oncology and confidence in both panitumumab and denosumab. Amgen is acquiring Abgenix for a total cash consideration of approximately $2.2b plus assumed debt. 2006-04-03T00:00:00 1 2200 0 0 753 Dental Danaher Corporation (NYSE: DHR) a leading manufacturer of professional instrumentation, industrial technologies, and tools and components. Sybron Dental Specialties Inc. (NYSE: SYD) a leading manufacturer of a broad range of consumables and small equipment for the dental professional, including the specialty markets of orthodontics, endodontics and implantology. Sybron’s consumables and small equipment offering are a logical extension of Danaher’s existing dental equipment portfolio and will allow us to more broadly serve the dental community.Danaher is to make a cash tender offer to acquire all of the outstanding shares of Sybron Dental for $47.00 per share, for an aggregate price of approximately $2.0 billion, including transaction costs and net of cash acquired, to be followed by a second step cash-out merger at the offer price. In addition, Danaher expects to assume approximately $200 million of debt in connection with the acquisition. 2006-04-12T00:00:00 1 2000 0 0 0 704 Biopharmaceuticals Watson Pharmaceuticals, Inc. (NYSE: WPI) a leading specialty pharmaceutical company that develops and distributes branded and generic drugs. Andrx Corporation (Nasdaq: ADRX) a producer of drug delivery technologies, including difficult-to-replicate generic products. Expands Watson's product portfolio and pipeline, while strengthening itss position in high value, specialized sustained-release technology. Deal price $1.9b cash. Subject to closing conditions. 2006-03-13T00:00:00 0 1900 1042 276 Medical Services North American Senior Care a consolidator of long-term care facilities. Beverly Enterprises, Inc. an operator of 350 nursing homes and assisted living centers In this $1.9 billion dollar deal, NASC has outbid other suitors in expanding its long-term care operations. The same group of investors behind NASC, in 2004, acquired Mariner Health Care, which had 250 skilled-nursing facilities in 27 states. A year before that, the investors acquired 130 facilities in 23 states from Integrated Health Services. 2005-08-17T00:00:00 0 1900 786 Diagnostics Siemens Medical Solutions (NYSE: SI) a supplier of diagnostic imaging technologies, healthcare information systems, and support services. Diagnostic Products Corporation a global leader in immunodiagnostics, focusing on manufacturing and distributing automated body fluid analyzers and tests for cancer and cardiac disease and hormone and allergy conditions. Furthers Siemens' objective to enable early and specific in vitro diagnosis and individualized patient therapy, as a forward move complementing its imaging diagnostic platform. The acquisition is another step in the development of integrated, clinical workflow-oriented solutions. Cash merger, with a deal price of $1.86b. DPC's trailing revenue and operating earnings were $481m (3.9x) and $96m (19.4x), respectively. Subject to regulatory approvals and other closing conditions. 2006-04-27T00:00:00 0 1860 481 96 277 Medical Services Omnicare Inc. (OCR) a provider of professional pharmaceuticals and related services to elderly care facilities. NeighborCare, Inc. a provider of institutional pharmacy services for long-term care and specialty and skilled nursing facilities. Also provides home care services, network retail pharmacies and group purchasing. Enhances Omnicare's position as a provider of pharmacy services for the elderly. The combined company will have a nationwide network of pharmacies serving long-term care providers. Total transaction value of approximately $1.8 billion. 2005-07-28T00:00:00 0 1800 292 Medical Services Conventry Health Care, Inc. (CVH) a managed health care company that operates health plans, insurance companies, and provider networks. First Health Group Corp. a national health benefits service company focused on the group health, workers’ compensation and state public program markets. Broadens the product portfolio and further diversifies the client base of the combined companies. Transaction value about $1.8 billion. 2004-10-14T00:00:00 0 1800 769 Biopharmaceuticals Millipore Corporation (NYSE: MIL) a bioprocess and bioscience and services company. Serologicals Corporation (NASDAQ: SERO) a developer of consumable biological products, enabling technologies and services in support of biological research, drug discovery and bioprocessing of life-enhancing products. Strengthens Millipore's Bioscience Division by giving it leading positions in a broad range of high growth segments such as drug discovery products and services, antibodies, cell biology reagents, and stem cell research. Millipore expects to increase sales of Serologicals' products in international markets such as Europe, Asia and Japan. Millipore will be the only company in the life science industry that can offer both upstream cell culture and downstream separation offerings for biopharmaceutical production, further strengthening its relationships with biotechnology and pharmaceutical customers. 2006-04-26T00:00:00 1 1400 0 0 0 24 Biopharmaceuticals Express Scripts (ESRX) a provider of pharmacy benefits management (PBM) pharmaceutical distribution services. Priority HealthCare (PHCC) a provider of specialty pharmacy and distribution services. Cash transaction of $1.3 billion. Positions and strengthens CuraScript as a leader in the specialty pharmaceutical marketplace (fertility, oncology, rheumatoid arthritis, hypertension, multiple sclerosis, etc.) , with over $3 billion in annual revenues. 2005-07-21T00:00:00 0 1300 589 Data Management/ Healthcare IT GE Healthcare (GE) a unit of General Electric Company providing medical imaging and information technologies. IDX Systems Corporation (IDX) a provider of software, services, and technologies for healthcare organizations. Expands the offerings of GE Healthcare Information Technologies, creating a comprehensive suite of clinical, imaging, administration, and electronic medical records systems. Transaction value -- $1.2b. IDX's revenues are $577m, its EBITDA $72.8m, and its net income $35.8m. 2006-01-06T00:00:00 0 1200 577 72.8 805 Biopharmaceuticals AstraZeneca PLC (NYSE: AZN) a major pharmaceutical company. Cambridge Antibody Technology Group PLC (NASDAQ: CATG) a manufacturer of drugs from human antibodies. Fortifies AstraZeneca's strategy of acquiring biotech companies to expand their drug portfolio. Cambridge Antibody Technology helped co develop Humira,a drug for rheumatoid arthritis and acquiring CAT's pipeline, which includes CAT-3888, in phase II development for cancer, and CAT-354, an asthma drug currently in phase I trials. Deal price was $1.32b. 2006-05-15T00:00:00 1 1032 0 0 0 281 Medical Services Onex Partners LP the private equity group of Onex Corporation (TSX:OCX). Laidlaw International Inc. (LI) a provider of transportation services. The acquisition provides Onex with two platforms of growth in the emergency medical services industry. Transaction value about $980 million. 2004-12-06T00:00:00 0 980 124 Diagnostics Quest Diagnostics Incorporated (DGX) a provider of diagnostic testing, information, and services for the healthcare industry. LabOne, Inc. (LABS) a provider of health screening and risk assessment services to life insurance companies; clinical diagnostic testing services to health care providers; and drug testing services to employers. Strengthens Quest's existing business and adds several new lines -- health screening and risk assessment services to the life insurance industry. Total transaction value of $934 million. LabOne's revenue and EBITDA were $490 million and $69 million, respectively. 2005-08-08T00:00:00 0 934 490 69 680 Medical Devices Angiotech Pharmaceuticals, Inc. a specialty pharmaceutical company that develops treatments for complications associated with medical device implants, surgical interventions and acute injury or trauma. American Medical Instruments Holdings, Inc. a leading independent manufacturer of a single-use medical device products for vascular surgery, interventional radiology, general surgery, wound closure, and minimally-invasive cosmetic surgery. By this definitive agreement, Angriotech, diversifies its revenue base and provides manufacturing, marketing and sales capabilities in a several therapeutic areas. AMI was formed in 2003 following the purchase of a majority interest in several medical technology companies by RoundTable Healthcare Partners from The Marmon Group. Deal value $785m, on sales $174m(4.5x). 2006-03-23T00:00:00 0 785 174 67.8 92 Data Management/ Healthcare IT Per-Se Technologies, Inc. a provider of billing, electronic claims processing and consulting services to providers. The physician, hospital and retail pharmacy businesses of NDC Health Corp. a healthcare data management and specialized services company. Per-Se to pay $665m for the acquired businesses, which synergize with and expand Per-Se's existing data management offerings. Separately, NDC sold Wolters Kluwer its publishing business. Acquired businesses had $225m in revenue (3x) and $32m in operating profit (20.8x). 2006-01-06T00:00:00 0 665 225 32 711 Biopharmaceuticals Dr. Reddy's Laboratories (NYSE: RDY ) an India-based emerging pharmaceutical company. Betapharm Group the fourth largest generics drug maker in Germany. Boosts Dr. Reddy's presence in Europe and increases company revenues by $200m (2.85X). Deal price -- $570m. 2006-03-04T00:00:00 0 570 200 0 629 Medical Devices Johnson & Johnson (NYSE:JNJ) a major pharmaceutical and medical device manufacturer. Animas Corporation (Nasdaq: PUMP) leading maker of insulin infusion pumps and related products. Fits with the J&J Lifescan unit, which makes glucose monitoring systems, and allows J&J to offer more comprehensive disease management solutions. Animas and Lifescan have worked in partnership for several years. Cash-for-stock transaction valued at about $518 million. Animas' market cap is over $450 million, but its revenue only $82 million and operating profits have been minimal. 2005-12-16T00:00:00 0 518 646 Medical Services UnitedHealth Group a large managed care organization. John Deere Health Care a regional managed care provider. This $500 million stock deal fills out UnitedHealth's network, geographical coverage and offerings. 2005-12-05T00:00:00 0 500 723 Medical Devices Coloplast A/S a Danish-based manufacture of products for ostomy, continence care, wound & skin care and breast care. The urology business of Mentor Corporation a manufacturer of products for the aesthetics, urologic specialties and clinical and consumer healthcare. This bid significantly enlarges the scope of Coloplast's urology business and strengths its position in Europe and the US. Upon closing of the deal, the combined annualized gross sales of Coloplast's urology and continence care products is estimated at $500m. Deal value -- $463m. Mentor urology's fiscal '05 sales were $232m (2X) and operating profits were $25.5m (18X). Subject to closing conditions. 2006-03-27T00:00:00 0 463 232 25.5 679 Medical Services Gentiva Health Services, Inc. (NASDAQ: GTIV) a large home health care provider. The Healthfield Group, Inc. a leading provider of home healthcare and hospice services. Extends Gentiva's geographic reach in the southeast, with Healthfied's 130 locations. Deal value $454m. 2006-01-05T00:00:00 0 454 0 727 Medical Services National Renal Institutes, Inc. healthcare services company based in Nashville, Tennessee, that operates kidney dialysis treatment clinics, hospitals and acute care centers. 100 dialysis clinics of Fresenius Medical Care AG & Co. KGaA the world’s largest provider of dialysis products and services. The divestiture is part of the antitrust requirements appurtenant to the merger of Fresenius and and Renal Care Group, Inc. Purchase price -- $450m cash. 2006-02-15T00:00:00 0 450 0 0 0 652 Medical Services Matria Healthcare, Inc. (Nasdaq: MATR) a leading provider of comprehensive health enhancement programs (for major chronic diseases and episodic conditions). CorSolutions Medical, Inc. a leading provider of disease management and related services. Expands Matria's offerings and organization to cover disease management and related areas: wellness, productivity, behavioral health, physician connectivity, pharmacy management, women's health, and commercialized informatics. Deal price $445m cash. CorSolutions's revenue and EBITDA were $120m (3.7x) and $38m(11.7x), respectively. 2006-01-22T00:00:00 0 445 120 38 796 Biopharmaceuticals Merck & Co., Inc. (NYSE: MRK) a leading pharmaceutical manufacturer. GlycoFi, Inc. a biotechnology company that specializes in optimizing biologic drug molecules. Enables Merck to develop novel biologic drugs by adding GlycoFi's scientific expertise, patent estate and robust technology platform. Deal resulted from prior strategic relationship. Deal price - $400m cash. 2006-05-09T00:00:00 1 400 0 0 0 288 Data Management/ Healthcare IT Wolters Kluwer NV a leading European publisher of medical, legal and other professional information. The pharmaceutical information management business of NDC Health Corp. a healthcare data management and specialized services company. Strengthens Wolter Kluwer's position in the growing pharmaceutical, biotech and medical device markets by expanding its business intelligence offerings. Deal price $382 million; NDC-IM expected to generate $165 million and adjusted EBITDA of $36 million in 2005. 2005-08-29T00:00:00 0 382 165 36 686 Medical Services Nuance Communications, Inc. (NUAN) a leading provider of speech and imaging solutions. Dictaphone Corporation a leading provider of dictation and speech recognition solutions for the health care industry. Accelerates Nuance's strategy to automate medical transcription. Expands Nuance's product portfolio and market reach (installed base of over 4,000 hospital and outpatient facilities and over 400,000 physicians). Deal value $359m in cash, subject to adjustments. Dictaphone fiscal '06 revenue about $80m (4.5x) and expected fiscal year '07 to exceed $180m. 2006-03-31T00:00:00 0 359 80 725 Biopharmaceuticals Ranbaxy Laboratories Limited a large India-based generic drug company. Terapia S.A. a Romania-based generic drug company. Provides major step for expanding Ranbaxy's European operations, with a broad product portfolio and deep pipeline. Ranbaxy will provide Terapia with additional products to launch in the domestic market at very cost competitive levels, thereby lowering costs and delivering value to both consumers and the domestic healthcare budget. Deal value $324m (11.6x LTM EBITDA and 4.05x sales of $80m). Being Eastern European based, Terapia's EBITDA margins are 35%. 2006-03-29T00:00:00 0 324 80 0 0 283 Medical Services Renal America, Inc. a newly-formed provider of dialysis services. 70 dialysis centers being divested by Davita and Gambro dialysis providers joined by DaVita's acquisition of Gambro. Grows Renal America to the fourth largest outpatient dialysis providers in the U.S. Backed by Welsh, Carson, Anderson & Stow, the deal size is $320.5 million. 2005-07-29T00:00:00 0 320.5 596 Diagnostics AmeriPath, Inc. a provider of anatomic pathology, dermatopathology and molecular diagnostic services. Specialty Laboratories, Inc. a provider of specialized clinical diagnostic testing services. Provides complementary services while broadening AmeriPath's base and expanding its geographic presence. Deal price $314.7m. 2006-02-01T00:00:00 0 314 632 Medical Devices dj Orthopedics, Inc. (DJO) a manufacturer of regeneration products for non-operative orthopedic and spine markets. Aircast, Inc. a manufacturer of bracing products for non-operative orthopedic, spine and vascular markets. Fortifies dj's presence with orthopedic surgeons and other providers by adding Aircast's strong ankle and vascular brands. Expands dj's distribution internationally where Aircast derives a third of its sales. Tailwind Capital sells Aircast for $290m cash; Aircast revenue and EBITDA were $96.8m (3x) and $24.4m (12x) respectively. 2006-04-10T00:00:00 0 290 96.8 24.4 719 Diagnostics Fisher Scientific International Inc. (NYSE: FSH) a leading provider of products and services to the scientific community. Athena Diagnostics, Inc. a venture-backed developer and provider of proprietary molecular diagnostic and immunodiagnostic tests. Deepens Fisher's portfolio of proprietary genetic and other markers; enhances its capabilities in personalized molecular diagnostics. Purchase from Behrman Capital for $283m on 2005 net revenues of $55m (5.1x). Subject to closing conditions. Simultaneous with its acquisition of Athena, Fisher entered into an agreement to purchase 9% of Nanogen, Inc. (Nasdaq: NGEN) for $15m in cash. Nanogen is a leading provider of advanced molecular diagnostic equipment, microarrays and reagents for diagnostic applications. Fisher and Nanogen will collaborate to expand the use of Athena's proprietary markers and tests. 2006-03-16T00:00:00 0 283 55 660 Biopharmaceuticals Applied Biosystems Group (NYSE: ABI) a leading supplier of life science research systems. The Research Products Division of Ambion, Inc. which specializes in the development of products for stabilizing, synthesizing, handling, isolating, storing, detecting and measuring RNA. ABI acquires a premium supplier of RNA-based reagents for life science research and drug development, for approximately $273 million in cash. Expected to close in Q1 2006. 2005-12-27T00:00:00 0 273 671 Data Management/ Healthcare IT Allscripts LLC a provider of healthcare information technologies, including electronic health records, e-prescribing, document imaging solutions and connectivity products. A4 Health Systems a developer of electronic medical records and practice management systems geared to small and midsized physician practices. Adds an established leader with a strong product offering and robust sales channel in two significant and underserved market segments - small, independent physician practices and mid-sized medical practice groups. A4's products can be integrated with Allscirpts's TouchWorks™ system. Deal price of $272m, on A4 revenues of $75m and EBITDA of $15.5m (3.6x and 17.5x, respectively). 2006-01-20T00:00:00 0 272 75 15.5 278 Distribution Omnicare Inc. (OCR) a provider of professional pharmaceuticals and related services to elderly care facilities. ExcelleRx a provider of pharmaceutical products and services to hospice agencies. Expands Omnicare’s hospice services and provides a platform for growth. Total purchase price of $269 million in cash. Total revenues for ExcelleRx at an annualized rate of $130 million. 2005-08-12T00:00:00 0 269 130 280 Medical Services Onex Corporation a diversified Canadian Investment Group. Center for Diagnostic Imaging, Inc. a provider of diagnostic and therapeutic radiology services, operating in 31 centers in 9 U.S. markets. Creates a new platform for Onex to grow in the diagnostic and radiology services market. Transaction value about $255 million; annual revenues exceed $125 million 2005-01-04T00:00:00 0 255 125 749 Medical Devices Hologic, Inc. (Nasdaq: HOLX ) a manufacturer of state-of-the-art diagnostic and digital imaging systems directed towards women's health. Suros Surgical Systems, Inc. a manufacturer of devices used for minimally invasive biopsy and tissue excision. Strengthens Hologic's capabilities in women's healthcare intiatives and offers a comprehensive portfolio of product offerings in breast cancer detection. Suros' expertise in breast biopsy combined with Hologic's resources should further accelerate Suros' ATEC® product line.The transaction will be structured as a merger of a Hologic acquisition subsidiary into Suros Surgical, whereby Suros Surgical will become a wholly owned subsidiary of Hologic.Deal price is $240m (subject to adjustment), plus a two-year earn out. The closing consideration will consist of $132m in cash and an additional $108m payable, at the election of Hologic, in cash, shares of Hologic Common Stock or a combination thereof. The earn-out will be payable in two annual cash installments equal to the incremental revenue growth in Suros Surgical's business in the two years following the closing. 2006-04-17T00:00:00 1 240 40 0 0 279 Medical Services Omnicare Inc. (OCR) a provider of professional pharmaceuticals and related services to elderly care facilities. RxCrossroads, L.L.C. a provider of distribution, product support and mail order pharmacy services for pharmaceutical manufacturers and biotechnology companies. Expands Omnicare's position as a provider of custom product solutions to pharmaceutical and biotechnology companies. Transaction value: $235 million. RxCrossroads revenues at an annualized Rate of $46 million. 2005-08-15T00:00:00 0 235 46 669 Diagnostics Becton, Dickinson and Company a major manufacturer of medical supplies and devices, laboratory equipment and diagnostic products. GeneOhm Sciences Inc. a pioneer developer of molecular diagnostic testing for the rapid detection of bacterial organisms. Provides BD with expanded entry into the emerging healthcare-associated infections (HAI) market. A natural complement to BD's core strengths in clinical microbiology. Deal value $230m, plus $25m in possible milestone payments, on sales of $5m. 2006-02-14T00:00:00 0 230 5 770 Diagnostics Hologic (NASDAQ:HOLX) a provider of diagnostic and digital imaging systems for women's health. R2 Technology a developer of a system for early detection for breast cancer. The acquisiton of R2 technology follows Hologic's recent acquisition of Suro Surgical. R2 Technology's system for early detection of breast cancer enhances Hologic's focus on women's health offerings. Deal Price is $220m, payable in shares of Hologic common stock. 2006-04-26T00:00:00 1 220 0 0 0 213 Medical Devices Ossur Ltd. (Iceland) a global manufacturer of orthotic and prosthetic devices. Royce Medical Holding Inc. a manufacturer and distributor of orthotic products (orthopedic braces and support; diabetic foot care and walkers; and collars for spine immobilization). Adds a non-overlapping O&P product line, increasing Ossur's US footprint against Otto Bock. Adds a major a field sales force and telemarketing staff. Acquisition cost of $216 million. Royce's sales are $68 million (3.2x) and EBITDA about $18 million (12x). $35 million in expected tax benefits. 2005-07-27T00:00:00 0 216 68 18 798 Medical Services Kendle International (NASDAQ: KNDL) a international clinical research organization. The Phase II-IV clinical services business of Charles River Laboratories International, Inc. (NYSE:CRL) a clinical research organization. Significantly enhances Kendle's global competitive position and adds high-value categories like oncology, infectious disease and respiratory disease. Deal price is $215m. 2006-05-10T00:00:00 1 215 0 0 0 1 Biopharmaceuticals Bausch & Lomb, Inc. a maker of contact lenses and eye medications. Shandong China Freda Pharmaceutical Group (China) an ophthalmic pharmaceutical subsidiary of Sino Biopharmaceutical Ltd. Aids B&L's expansion in the Chinese market. Acquisition of a 55% interest for $200m cash, representing 18.6x 2004 net earnings. B&L will buy and additional 15% for $54.5 million from two other entities. 2005-07-05T00:00:00 0 200 716 Diagnostics Inverness Medical Innovations, Inc. (Amex: IMA) a provider of diagnostic products for women’s health and chronic disease self-management. The lateral flow immunoassay diagnostic products ACON Laboratories, Inc. a provider of diagnostic test kits for the consumer, point-of-care and laboratory markets. The deal settles Inverness' patent infringement claims against ACON and fortifies Inverness' position in pregnancy and fertility testing consumer markets. The business to be acquired had 2005 revenues and operating income of approximately $50m (3.5x) and $17m (10.3x), respectively. Deal price of $175m (including a manufacturing plant in China providing low cost production and distribution). 2006-02-24T00:00:00 0 175 50 17 692 Medical Devices C. R. Bard, Inc. (NYSE:BCR) a multinational manufacturer of medical technologies for vascular, urology, oncology and surgical specialty products. Venetec International, Inc a manufacturer of the StatLock® line of catheter securement systems. With this $166m cash acquisition agreement, Bard Medical adds a leading complementary line of catheter securement devices, used primarily in acute care facilities, to reduce complications with peripheral intravenous (IV) catheters. The StatLock line replaces tapes and sutures, which can come loose and raise the risk of infection at the catheter site. Venetec's sales estimated at about $34m. 2006-04-10T00:00:00 0 166 34 758 Medical Services Concentra Operating Corporaton a leading provider of outsourced workers' compensation, occupational healthcare and cost containment services for group health insurance companies, payer organizations and medical providers. Beech Street Corporation a leading full-service preferred provider organization. Expands Concentra's offerings in the group health market and enhances its existing lines of service to the nation's leading health plans, insurers and third-party administrators. Deal value -- $165m on revenue of $70m (2.4x) 2005-10-03T00:00:00 0 165 70 0 21 Biopharmaceuticals Cephalon Inc. a developer of drugs to treat and manage neurological diseases, sleep disorders, cancer and pain. Salmedix Inc. a drug-development company focusing on treatments for blood cancers. The $160 million deal expands Cephalon's cancer drug offerings. 2005-05-13T00:00:00 0 160 662 Data Management/ Healthcare IT WebMD Corp. a major vendor or transactions processing, physicians office software and Web-based medical information content. ViPS Inc. a provider of software for claims processing, HEDIS reporting, provider performance measurement, case management, and predictive modeling. Complements WebMD's offerings to providers, helps to strengthen its information system franchise and opens up the government sector, ViPS' major market. $160 million deal value. ViPS' sales and EBITDA were about $59 million and $17 million, respectively. 2004-07-12T00:00:00 0 160 59.1 14 112 Diagnostics Laboratory Corporation of America Holdings (NYSE:LH) an independent clinical laboratory company. Esoterix, Inc. a provider of specialty lab testing services. Esoterix is being sold Behrman Capital, a private equity firm for $150 million cash. Esoterix was a "roll-up" of fragmented lab service companies. It will add a number of well-known offerings to LabCorp's existing portfolio. 2005-03-30T00:00:00 0 150 792 Biopharmaceuticals Biogen Idec (NASDAQ: BIIB) a manufacturer of novel therapies, Biogen Idec creates new standards of care in oncology, neurology and immunology. Conforma Therapeutics Corporation a biopharmaceutical company focused on the design and development of novel drugs for the treatment of cancer. Provides significant opportunities for Biogne Idec to develop drugs for a range of solid tumors using Conforma's platforms of HSP90 antagonists and broaden their therapeutic opportunities in the cancer field. Biogen Idec will acquire all of the issued and outstanding shares of the capital stock of Conforma for $150 million, payable at closing, and up to an additional $100 million upon the achievement of certain development milestones. 2006-05-03T00:00:00 1 150 0 0 0 717 Biopharmaceuticals Johnson & Johnson (NYSE:JNJ) a provider of healthcare products and services to the consumer, pharmaceutical, medical devices, and diagnostics markets. ColBar LifeScience an Israeli-based based, venture-backed producer of collagen implants. J&J accesses two promising ColBar collagen products in fast growing artificial tissue segments: one for encouraging bone growth in the jaw for dental applications and the other for treating facial wrinkles (the aesthetic market). Pipeline products address urological, orthopedic and other fields. Deal value $140m. ColBar’s has several million dollars in sales, mostly in Europe. Subject to closing conditions. 2006-03-15T00:00:00 0 140 0 2 650 Medical Services Magellan Health Services, Inc. (Nasdaq:MGLN) a leading behavioral health care management organization. National Imaging Associates, Inc. a privately held radiology benefits management firm. In this $122 million deal, Magellan diversifies its behavioral health core to provide benefits management in the fast growing radiology field, while leveraging its strengths in underwriting, claims payment and provider network management. Cash flow from operations for NIA during the 10 months is expected to be approximately $9 million. 2005-12-13T00:00:00 0 122 9 100 Diagnostics Affymetrix, Inc. a producer of microarrays and molecular biology products. ParAllele BioSciencea producer of microarrays and molecular biology products. a producer of microarrays and molecular biology products. ParAllele provides proprietary assays and microarray solutions to enable Affymetrix to access more genetic information in less time and for less expense. The companies had been collaborators on several projects. A stock deal worth ~ $120 million. 2005-06-01T00:00:00 0 120 241 Medical Devices Boston Scientific Corporation (BSX) a manufacturer of medical device products for interventional medical specialties. Advanced Stent Technologies, Inc. (AST) a developer of stent and stent delivery systems for coronary artery disease and bifurcated vessels. BSX will own Petalä a stent design developed by AST. Petal complements BSX’s paclitaxel-eluting stent technology. Transaction value about $120 million. 2005-03-04T00:00:00 0 120 634 Medical Devices Encore Medical Corporation (Nasdaq: ENMC) a diversified orthopedic device manufacturer. Compex Technologies, Inc. a leader in designing and manufacturing transcutaneous electrical nerve stimulation and electrical muscle stimulation (EMS) products used for pain management, rehabilitation and other medical settings. Creates a stronger orthopedic products company that will combine leading electrical stimulation pain management and rehabilitation companies -- Encore's Orthopedic Rehabilitation Division, which includes Empi and Chattanooga Group, and Compex, formerly Rehabilicare. Transaction valued at approximately $109m. Compex's sales for fiscal 05 were $96.1m (1.13x) and its operating profit was $4.6m (22.4x). 2006-02-27T00:00:00 0 109 96.1 4.6 787 Medical Services RehabCare Group, Inc. (NYSE: RHB) a provider of rehabiltation program management. Symphony Health Services LLC a provider of contract therapy services. Expands RehabCare's organization to be one of the largest providers of rehabilitation program management services in the US. The deal includes Symphony's RehabWorks subsidiary, a provider of services to long-term care facilities. Deal price is $101.5m. 2006-05-03T00:00:00 1 101.5 0 0 0 751 Medical Devices Integra LifeSciences Holdings Corporation (Nasdaq:IART) a diversified manufacturer of neuro, reconstructive and general surgery products. Miltex, Inc. a leading provider of surgical and dental hand instruments to alternate site facilities. Expands Integra's instrument lines and opens up private physician, dental and ambulatory surgery care sectors. Deal value -- $101m cash. Miltex's 2005 revenues were $62m (1.63x) and operating EBITDA $13m (7.8x). Miltex is a portfolio company of American Securities Capital Partners, L.P., a private equity firm. Subject to closing conditions. 2006-05-12T00:00:00 0 101 62 13 78 Data Management/ Healthcare IT Cerner Corporation (CERN) a leading provider of healthcare information technologies. VitalWorks Inc. (Nasdaq:VWKS) a provider of information and image management products and services. VitalWorks divests its medical division to Cerner. Transaction, valued at about $100 million, expands Cerner’s existing products and services focused on the physician practice market. VitalWorks changes its name to AMICAS and will focus on the radiology market. 2005-01-03T00:00:00 0 100 103 Diagnostics Beckman Coulter, Inc. a manufacturer of laboratory automation products. Agencourt Bioscience Corporation a provider of genomic services and nucleic acid purification products. Agencourt's patented RNS and DNA isolation and purification products are used with Beckman Coulter's Biomek® automated liquid handling systems. Beckman Coulter plans to use the products in automated sample preparation systems for biomedical research and molecular testing. $100 million stock purchase, with possible $40 million in contingent payments. 2005-04-27T00:00:00 0 100 234 Medical Devices Viasys Healthcare Inc. (VAS) a provider of respiratory, neurology, medical disposable and orthopedic products. Pulmonetic Systems a manufacturer of portable mechanical ventilators for home healthcare. With its strong respiratory brands, Viasys adds a new business segment, the fast-growing home-care mechanical ventilation market. Pulmonetic posted revenues of $42 million in 2004. Transaction value about $98 million. 2005-05-18T00:00:00 0 98 42 644 Medical Devices Bespak plc (UK) a developer of new delivery systems for the pharmaceutical industry (i.e., metered dose inhalers, dry powered devices, actuators, etc.) King Systems Corporation a provider of respiratory products (i.e., face masks, breathing circuits and laryngeal tubes). This $95m cash and stock acquisition diversifies Bespak's product line and opens up direct sale channels into the hospital. The deal also strengthens Bespak's U.S. footprint. King's 2004 sales and adjusted EBITDA were $45m and $8.2m, respectively. $10m of the price is based on EBITDA milestone attainment. 2005-12-09T00:00:00 0 95 45 8.2 741 Biopharmaceuticals EPIX Pharmaceuticals, Inc. (NASDAQ: EPIX) a developer of pharmaceuticals for imaging that are designed to transform diagnosis, treatment and monitoring of disease. Predix Pharmaceuticals Holdings, Inc. a developer of highly selective, small-molecule drugs that target G-Protein Coupled Receptors and ion channels. Using its proprietary drug discovery technology, it has advanced three internally discovered drugs into clinical trials. The combined company will license its later-stage products to larger pharmaceutical or biotechnology companies to maximize the value of these products. Combines EPIX's approved product in Europe, Phase II candidate, preclinical compounds, operating infrastructure, cash and access to capital with Predix's therapeutic product pipeline, which will maximize the development and partnership opportunities for lead therapeutic products. Deal Price $90m with a potential milestone payment of $35m. 2006-04-03T00:00:00 1 90 0 0 0 190 Medical Devices Integra Life Sciences Holding Corporation (IART) a manufacturer of neuro and plastic surgical products. Tyco's Radionics Division a manufacturer of minimally-invasive medical instruments for neurosurgery and radiation therapy. Increases Integra's global neurosurgery offerings, adding ultrasonic aspirators and stereotactic head frames, and permits entry into the radiosurgery/therapy and image guides therapy segments. Radionics generated $62.5m in revenues and $13.4m in pretax earnings. Deal price of $80m cash -- 1.28x revenue; 6x pretax. 2006-03-05T00:00:00 0 80 62.5 13.4 797 Biopharmaceuticals Merck & Co., Inc. (NYSE: MRK) a leading pharmaceutical manufacturer. Abmaxis, Inc. a biopharmaceutical company dedicated to the discovery of monoclonal antibody products for human therapeutics and diagnostics. Provides Merck with the opportunity to optimize and discover antibodies. Complements Merck's contemporaneous purchase of GlycoFi. Another outgrowth of a prior strategic relationship. Deal price is $80m in cash. 2006-05-09T00:00:00 0 80 0 0 0 683 Medical Devices Moog Inc. a manufacturer of precision control components and systems for military and commercial aircraft, satellites and space vehicles, industry machinery, and medical equipment. Curlin Medical LLC a manufacturer of "smart" ambulatory infusion pumps for pain management and other applications. Moog's expertise in the electronic control of fluid-flow metering devices combined with Curlin's reputation in the medical market is expected to facilitate the continued growth of Moog's medical equipment sales. Deal value $75m ($63m in cash). Curlin's 2005 sales were $16m (4.7x) and its operating profits were $5.4m (13.9x). '06 sales are running at almost double the rate of '05. The Walden Group was retained by Moog, identified Curlin on Moog's behalf, and initiated this transaction. 2006-04-11T00:00:00 0 75 16 5.4 729 Diagnostics Serologicals Corporation (NASDAQ: SERO) a manufacturer of diagnostic products for biological research and drug discovery. LINCO Research Inc. a manufacturer of immunoassay reagents, kits and services in the endocrinology and metabolic disease field. Strengthens Serological's Luminex-based Multiplexing (multiple reaction product) portfolio and enables it to address the metabolic disease research market. Deal value -- $64.5m cash and $10.3m for land and buildings (deal value 3.4x times projected LINCO sales of $22.0m). 2006-03-23T00:00:00 0 74.8 22 0 0 165 Medical Devices Cantel Medical Corporation (CNM) a provider of infection prevention and control products, including specialized medical device reprocessing systems. Crosstex International, Inc. a manufacturer and reseller of single-use infection control products, principally in dental markets. Extends Cantel's infection control business into the dental arena, for a purchase price of $74.2 million in cash and stock. Additional $12.0 million potential earnout payable over three years. Crosstex reported revenue of $47.4 million for fiscal year ending April 30. Cantel posted fiscal-year revenue of $170 million. 2005-08-03T00:00:00 0 74.2 47.4 284 Medical Services Steris Corporation (STE) a provider of anti-infection and anti-contamination products. Cosmed Group, Inc. a sterilization services provider. Cosmed’s five medical device sterilization locations augment Steris’s Isomedix Services sterilization network. Transaction value about $73 million, more than 3X Cosmed’s revenues of $21 million. 2005-01-07T00:00:00 0 73 21 637 Medical Services Accredo Health Inc. a subsidiary of Medo Health Solutions, a manager of drug benefits programs. Pediatric Services of America Inc. (PSAI) a provider of pediatric private duty nurses. In this $72 million deal, Accredo acquires the specialty pharmacy business of PSAI, which is complementary. 2005-12-20T00:00:00 0 72 111 Diagnostics Inverness Medical Innovations, Inc. (IMA) a provider of diagnostic products for women’s health and chronic disease self-management. Rapid Diagnostic tests from Abbott Laboratories a major pharmaceutical, medical device and diagnostic test manufacturer. Strengthens its IP portfolio as well as its diagnostic business. Deal price of $56.5 million cash. 2005-06-30T00:00:00 0 56.5 565 Medical Services PolyMedica Corporation (PLMD) a provider of healthcare products and services to patients suffering from chronic diseases. National Diabetic Pharmacies a provider of mail-order diabetes supplies, prescription medications and related services. Allows PolyMedica significant entry into the commercial market. Transaction valued at $55 million. 2005-08-05T00:00:00 0 55 641 Medical Services Humana Inc (NYSE:HUM) one of the nation's largest health benefits companies, with about 7 million medical members. Corphealth Inc. a behavioral health care management company. In this $54 million cash deal, Humana acquires a nationwide network of 22,000 behavioral health providers and serves about 2 million members. 2005-12-22T00:00:00 0 54 582 Diagnostics Inverness Medical Innovations, Inc. (IMA) a provider of diagnostic products for women’s health and chronic disease self-management. Thermo BioStar the point-of care and rapid diagnostics business of Thermo Electron, a maker of laboratory tools. Provides Inerness with complementary product lines, and a direct sales force of 55 people to market directly to doctors' offices and hospitals. Transaction value $52.5 million. Thermo BioStar is profitable and had revenue for the first half of 2005 of $18.5 million. 2005-09-19T00:00:00 0 52.5 35 642 Medical Devices St. Jude Medical, Inc. (NYSE:STJ a manufacturer of cardiovascular medical devices. Savacor, Inc. a developer of heart failure diagnostic and therapy guidance products and technologies in clinical evaluation. Savacor's small implantable sensor, in clinical trials, measures left atrial pressure and body temperature to help physicians detect and manage symptoms associated with progressive heart failure. The deal, valued at $50m plus possible milestone payments, complements St. Jude's development efforts in managing the co-morbidities of heart failure patients. 2006-01-03T00:00:00 0 50 782 Medical Devices American Medical Systems Holdings, Inc. (NASDAQ:AMMD) a diversified supplier of medical devices and procedures to cure erectile dysfunction, benign prostatic hyperplasia, incontinence, menorrhagia, prolapse and other pelvic disorders in men and women. assets from BioControl Medical, Ltd., an Israeli-based developer of medical devices for the application of implantable electrical stimulation technology. Combines BioControl's implantation technology, the miniaturo™ system, with American's presence in the urology and gynecological markets to broaden the application of electrical stimulation technology to pelvic health conditions. Deal price is comprised of an initial payment and milestone payments (for relevant accomplishments through and including FDA approval of the product) totaling $50 million and royalties over the first ten years of the related license agreement. 2006-04-26T00:00:00 1 50 0 0 0 606 Medical Devices Accellent, Inc. a provider of contract manufacturing and design services to medical device manufacturers. Machining Technology Group (MTG) a contract manufacturer producing orthopedic implants and devices. The $50 million acquisition strengthens Accellent's position in the orthopedic Market. 2005-10-06T00:00:00 0 50 677 Data Management/ Healthcare IT Misys Healthcare Systems a clearinghouse of electronic healthcare transactions. Payerpath Inc. a provider of internet solutions for processing healthcare claims. Synergizes with Misys' electronic transaction clearinghouse operations. Deal value $49m. 2006-01-31T00:00:00 0 49 0 13 268 Medical Services Concentra Health Services a leading provider of outsourced workers' compensation, occupational healthcare and cost containment services for group health insurance companies, payer organizations and medical providers. Occupational Health + Rehabilitation (OHRI) a provider of occupational healthcare services, with 34 centers in 10 states. Extends Concentra's reach to six new states and strengthens the presence of its existing network. Deal price $48.6 million plus retained cash. OH+R's revenue was $57million. After the integration, Concentra will have 294 centers in 40 states. 2005-08-08T00:00:00 0 48.6 57 810 Diagnostics Trinity Biotech plc. (NASDAQ NM: TRIB) a leading developer and manufacturer of diagnostic products for the point-of-care and clinical laboratory markets the coagulation product line from bioMerieux. a global leader in in vitro diagnostics. Following the merger of Trinity's existing Biopool and Amax Coagulation product lines with bioMérieux, it is estimated that Trinity's share of the $600m worldwide Coagulation market will be 13%. The target lines can be sold via Trinity's sales force. The bioMérieux coagulation product line comprises a comprehensive portfolio of diagnostic tests and automated instruments. Deal price is $46.4 plus $5.5m in contingent payments. Expected to add $40m in revenue and $5m in EBTDA to Trinity. Subject to closing conditions. 2006-05-25T00:00:00 0 46.4 40 5 599 Medical Services Amerifit Nutrition, Inc. a health and wellness-products company and a unit of Charterhouse Financial. The women's health products division of PolyMedica Corporation a provider of diabetic supplies blood glucose testing supplies. In this $45 million deal, Amerifit, buys a leading manufacturer and marketer of OTC and prescription products oriented toward urinary tract health. The division accounted for $16.8 million in net revenue and $6.8 million in operating income for the fiscal year that ended March 31. 2005-10-03T00:00:00 0 45 16.8 6.8 568 Medical Services Vision Acquisition Corporation an affiliate of Berkshire Partners LLC - a private equity investor. National Vision, Inc. (NVI) an operator of retail vision centers. The merger will combine NVI and CVG into the fourth largest retail optical chain in the United States. The cash tender offer by Vision Acquisition Corp, is for a total value of $43 million - approximately 85.1% of the outstanding shares. Consummation of the tender offer is subject to the completion of NVI's acquisition of Consolidated Vision Group, in which NVI will pay approximately $88 million in cash. 2005-09-12T00:00:00 0 43 555 Medical Services Berkshire Partners LLC a private equity investor. National Vision, Inc. (NVI) an operator of retail vision centers. Deal value - $43 million for 85.1% of the outstanding shares. Subject to the completion of NVI's acquisition of Consolidated Vision Group, in which NVI will pay approximately $88 million in cash. The merger will combine NVI and CVG into the fourth largest retail optical chain in the United States. 2005-09-12T00:00:00 0 43 109 Diagnostics Inverness Medical Innovations, Inc. (IMA) a provider of diagnostic products for women’s health and chronic disease self-management. Binax, Inc. a developer of rapid diagnostic products for infectious disease testing. Expands Inverness’s proprietary technology base into respiratory and other infectous disease diagnostics. Deal value: approx. $33 million in Inverness stock plus $8.6 million in cash, with $11 million of contingent payments (meeting product development hurdles). Binex had sales of $20 million. 2005-02-08T00:00:00 0 41.6 705 Biopharmaceuticals Cardinal Health, Inc (NYSE: CAH) a major pharmaceutical and medical device distributor. ParMed Pharmaceuticals, Inc. the generic pharmaceutical telemarketing distribution business of Alpharma Inc. (NYSE: ALO), a specialty pharmaceutical company. Adds telemarketing resources to Cardinal and streamlines Alpharma in respect of its core competencies. Deal price $40.1m in cash. 2006-03-08T00:00:00 0 40.1 0 621 Data Management/ Healthcare IT Emageon, Inc. a developer of digital image management systems for radiologists. Camtronics Medical Systems, Ltd. a leading developer of cardiovascular information systems and hemodynamic monitoring technology and a unit of Analogic Corp. The $40 million cash purchase gives each company an entrée into the other's markets. Camtronics currently markets to 350 hospitals, and Emageon markets to 250. Camtronics's 2004 revenue was about $38 million. 2005-11-11T00:00:00 0 40 672 Medical Devices Ossur hf. (ICEX: OSSR) a global orthopaedics company specialized in prosthetics. Innovation Sports, Inc. a US-based developer and manufacturer of ligament braces. The acquisition of Innovation Sports follows Ossur's July 2005 acquisition of Royce Medical in U.S., and the December 2005 acquisition of IMP Holdings in the UK. These acquisitions, together with Ossur's 2003 acquisition of Generation II, enhance Ossur's presence in the braces and support market. Deal value of $38.4m, on sales of $19m(2x) and normalized EBITDA of $3.61m(10.6x). 2006-01-19T00:00:00 0 38.4 19 3.61 757 Medical Services Hooper Holmes, Inc. a provider of health and other underwriting information on insurance policy applicants to the life insurance industry. D & D Associates a provider of independent medical examinations. Enables HH to enter the $2 billion plus IME market, as a complement to its core health information business. HH intends to expand D&D's services beyond its NYC metro market. Deal value -- $38m, on pro forma sales and EBITDA of $30m (1.3x) and $6.0m (6.3x), respectively. 2002-11-04T00:00:00 0 38 30 6 784 Medical Devices MediCor Ltd. (OTC: MDCR ) a manufacturer of products for medical specialties in the aesthetic, plastic and reconstructive surgery and dermatology markets. Biosil Limited and related supplier Nagor Limited UK-based Biosil develops and manufactures, and Nagor markets, a full range of silicone implants including silicone gel and saline-filled breast implants along with other silicone devices and scar management products. Strengthens MediCor's strategy of acquiring the most respected businesses in the global aesthetic, plastic and reconstructive surgery and dermatology markets by expanding upon Biosil and Nagor's manufacturing, sales and marketing structures. Deal price is $36.9m and 2.64m shares of MediCor common stock. The combined purchase price for the two companies was 20m pounds sterling (36,956,963. US) in cash and 2.64 million shares of MediCor common stock. 2006-04-28T00:00:00 1 36.91 0 0 2 752 Medical Services WebMD Health Corp (Nasdaq:WBMD) a leading provider of online health information services to consumers and physicians. Summex a provider of comprehensive health and wellness programs that include online and offline health assessments, lifestyle education and telephonic health coaching. Further strengthens WebMD's offerings to change high-risk behaviors that lead to illness and high medical costs. Compliments it's online health and benefits platform that WebMD provides to large employers and health plans. Deal price is $30m in cash at closing and WebMD has agreed to pay up to an additional $10 million in cash over a two year period if certain milestones are achieved. 2006-04-17T00:00:00 1 30 0 0 0 718 Biopharmaceuticals Pharmos Corporation (Nasdaq: PARS) a developer of therapeutics to treat disorders of the central and peripheral nervous systems and systemic disorders involving inflammation and autoimmune dysfunctions Vela Pharmaceutical, Inc. a venture-capital backed, privately owned company specializing in the development of medicines related to diseases of the nervous system including disorders of the "brain-gut axis." Creates a combined drug development company focused primarily on diseases of the nervous system and autoimmune disorders. Deal value about $29.7m -- $5.0m cash; balance Pharmos stock, plus additional stock if clinical milestones are hit. 2006-03-17T00:00:00 0 29.7 0 0 808 Biopharmaceuticals Avanir Pharmaceuticals (NASDAQ: AVNR) a pharmaceutical developer of therapeuticsto treat chronic diseases. Alamo Pharmaceuticals, LLC a specialty pharmaceutical company focused on selling drugs to treat schizophrenia. Strategic step toward Avanir becoming an integrated pharmaceutical company and enhances their portfolio by adding a marketed CNS products. Deal price is $29m with milestone payments of up to $40m. 2006-05-23T00:00:00 0 29 0 0 0 794 Biopharmaceuticals YM BioSciences Inc. (AMEX:YMI, TSX:YM, AIM:YMBA) a cancer product development company. Its lead drug, tesmilifene, is a small molecule chemopotentiator currently undergoing a Phase III trial in metastatic and recurrent breast cancer. Eximias Pharmaceutical Corporation a privately-held pharmaceutical company engaged in the acquisition, development and commercialization of products for the treatment of cancer and cancer-related disorders. Expands YM capabilities for the development and commercialization of its products currently in clinical development and establishes a presence for YM in the USA, particularly within the oncology and financial communities. Deal price is $29m. 2006-05-09T00:00:00 1 29 0 0 0 110 Diagnostics Inverness Medical Innovations, Inc. (IMA) a provider of diagnostic products for women’s health and chronic disease self-management. Ischemia Technologies, Inc. a venture-backed manufacturer of diagnostic tests for cardiovascular and acute care medicine. Ischemia helps Inverness expand in the cardio market; Inverness can help to commercialize the Ischmia products. Ischemia had only $1million in revenue. A $22.4 million deal in Inverness stock. 2005-02-16T00:00:00 0 22.4 1 567 Diagnostics Caliper Life Sciences, Inc. (CALP) a provider of instruments and consumables used in the pharmaceutical and biotechnology industries. NovaScreen Biociences a provider of screening, profiling and assay development services. Leverages combined expertise and technologies in the growing screening and profiling market. Transaction value $22 million in stock and cash with an additional $8 million in milestone payments. 2005-09-08T00:00:00 0 22 661 Biopharmaceuticals EntreMed, Inc. (NASDAQ: ENMD) a clinical stage pharmaceutical company developing therapeutics for cancer and inflammatory diseases. Miikana Therapeutics, Inc. a biopharmaceutical company focusing on cancer drugs. Expands EntreMed's oncology pipeline. A stock deal work about $21.2 million, plus a possible $18 million if milestones achieved. 2005-12-22T00:00:00 0 21.2 696 Medical Services Covalent Group, Inc.,(NASDAQ: CVGR) a producer of design and management of complex clinical trials and patient disease registries for pharmaceutical, biotechnology and medical device industries. Remedium Oy a clinical research organization. Upon closing, combined company will be named Encorium BioSolutions Inc. and will enable its complex clinical trials and patient registries to expand globally. Deal value -- $16m stock, $4m cash. Combined company projects annualized revenue between $21-$23m. 2006-03-06T00:00:00 0 20 0 0 0 113 Diagnostics Life Therapeutics, Ltd. (LFE.AX) a biotechnology company which offers a complete cycle of plasma derived products and services. Pyramid Biological a plasma and biodiagnostic supplier. The acquisition increases Life's plasma collection capacity and increases its share of plasma markets. Consists of $13 million plus assumption of $7 million debt. An additional $5 million is subject to milestones. The forecast of projected sales for US fiscal year 2006 is $54.8 million with a projected earnings of $7.4 million EBITDA. Life Therapeutics expects to achieve significant cost savings thru synergies. 2005-07-15T00:00:00 0 20 54.8 7.4 618 Data Management/ Healthcare IT WebMD Health Corp (Nasdaq:WBMD-News) a leading provider of health information services. Conceptis Technologies Inc. a Canadian developer of online information systems for certain medical specialties. Conceptis’ focus on cardiology, nephrology, and hematology adds strength to WebMD’s medical marketing offerings. $19 million cash deal. 2005-11-11T00:00:00 0 19 714 Medical Devices Ossur hf. (ICEX: OSSR) leading global supplier of prosthetic and orthopedic devices. Innovative Medical Products Holdings Ltd. a U.K. producer and distributor of knee, hip and spinal braces. Benefits of this $18.5 million acquisition include: (a) the integration of a strong U.K. sales network; (b) the enhancement of a sales network throughout Europe; and (c) the addition of Medistox and Technology in Motion brands. IMP had 91 employees, sales of about $14 million (1.24x) and EBITDA of approx. $2.70 (6.8x). 2005-12-01T00:00:00 0 18.5 14 2.7 700 Diagnostics Varian, Inc. (VARI) a supplier of scientific instruments, vacuum technologies and specialized contract electronics manufacturing services. IonSpec Corporation a manufacturer of Fourier Transform mass spectrometry technology to discover the function and structural characterization of proteins and other biomolecules in various biological systems. Increases Varian's participation in faster growing life science applications, in particular in the study of proteins, nucleic acids and drug metabolites. Deal value $16m, plus milestones. 2006-02-28T00:00:00 0 16 0 651 Medical Devices dj Orthopedics, Inc. (DJO) a manufacturer of regeneration products for non-operative orthopedic and spine markets. Newmed SAS (France) a manufacturer of orthopedic rehab devices, including rigid knee braces and soft goods. Increases the scale of dj's international business and in France in particular. Deal price $15.6 million, plus another $1.2 million in contingent payments. Newmed's revenues are about $12 million. 2005-12-15T00:00:00 0 16 806 Biopharmaceuticals China Biopharmaceuticals Holdings, Inc. ("CBH")(OTC Bulletin Board: CHBP ) a leading Chinese pharmaceutical company focused on the development, manufacturing and distribution of innovative drugs in China RACP Pharmaceutical Holdings Ltd. ("RACP"), including Shenyang Enshi Pharmaceutical Co.,Ltd. ("Enshi"), a leading manufacturer and distributor of pharmaceutical products in China. Further bolsters CBH's already robust production and distribution capabilities and enhances their operational and financial profile by a focused strategy of scientific and operational leadership, opportunistic participation in market consolidation, and continued expansion of product and service offerings. Deal price is $16m. 2006-05-17T00:00:00 1 16 0 0 0 587 Medical Services PainCare Holdings Inc. a provider of pain management services. The Center for Pain Management ASC LLC an owner and operator of ambulatory surgery centers. The $15 million transaction in cash and restricted shares provides PainCare with enhanced market penetration. The acqusition is forecasted to contribute more than $4.5 million in revenues and approximately $3 million in operating income to PainCare by year-end 2006. 2005-09-26T00:00:00 0 15 4.5 3 636 Medical Services MSO Holdings an obesity disease management company. Resources for Living a behavioral wellness company. This $15 million deal combines two complementary behavioral wellness companies. 2005-11-17T00:00:00 0 15 720 Diagnostics Fisher Scientific International Inc. (NYSE: FSH) a leading provider of products and services to the scientific community. Nanogen, Inc. (Nasdaq: NGEN) a leading provider of advanced molecular diagnostic equipment, microarrays and reagents for diagnostic applications. Fisher and Nanogen will collaborate to expand the use of the proprietary markers and tests of Athena Diagnostics, Inc., which Fisher announced it was purchasing together with its acquisition of 9% of Nanogen's stock for $15 million. 2006-03-16T00:00:00 0 15 0 0 287 Medical Services Ventiv Health, Inc. (VTIV) a provider of outsourced clinical, sales, marketing, and compliance solutions for the pharmaceutical, biotechnology and life sciences industries. Pharmaceutical Resource Solutions, LLC a provider of compliance management and marketing support services for the pharmaceutical and healthcare industry. Strengthens Ventiv's commercial services division among smaller sizes companies, a key audience for outsourced services. The transaction is valued at $13 million. Ventiv (the acquirer) currently has revenue of $459 million and EBITDA of $63 million. 2005-08-08T00:00:00 0 13 698 Medical Services BioScrip, Inc. (NASDAQ: BIOS) the survivor of the Chronimed-MIM merger Corporation merger -- a large provider of comprehensive pharmaceutical care solutions. Intravenous Therapy Services (ITS) a specialty infusion company. Enhances BioScrip's ability to service infusion patients nationally. Deal price is $13m cash, plus potential earn-outs. ITS' revenue is $9m. 2006-03-02T00:00:00 0 13 9 0 584 Diagnostics Clinical Data, Inc. (CLDA) a provider of blood chemistry instruments and diagnostic assays to physician offices, clinics and small hospitals. Icoria, Inc. (ICOR.OB) a developer of biomarker discovery platforms with multi-analyte diagnostic capabilities which define and grade pathology or disease states. The all-stock transaction valued at $12.5 million strengthens CD's position in targeted diagnostics and theranostics and brings metabolomics and biomarker expertise to CD. 2005-09-20T00:00:00 0 12.5 722 Biopharmaceuticals Dynavax Technologies (NASDAQ:DVAX) a developer of products to treat allergies, infectious diseases, and chronic inflammatory diseases using proprietary approaches that alter immune system responses. Rhein Biotech GmbH a German manufacturer of antigens. Dyavax gains ownership of a European Union (EU) GMP-certified vaccine manufacturing facility, control over the production of antigens to support clinical and commercial programs, and a complementary pipeline of vaccine and antiviral products. Deal value --approximately $12m cash; expected to close in 2Q06. 2006-03-27T00:00:00 0 12 0 0 0 804 Medical Services Radiation Therapy Services, Inc. (NASDAQ: RTSX) a leading operator of radiation therapy centers. a radiation treatment facility in Santa Monica, CA. a facility with an Intensity Modulated Radiation Therapy (IMRT) program. Broadens Radiation Therapy's presence in Southern California by entering the Los Angeles local market. Deal price is $11m. 2006-04-27T00:00:00 1 11 0 0 0 742 Diagnostics IRIS International, Inc. (NASDAQ:IRIS) a manufacturer and marketer of automated IVD urinalysis systems and medical devices. Leucadia Technologies, Inc. a molecular diagnostics company. Strengthens IRIS' strategic position and significantly broadens its product portfolio by adding a molecular diagnostics platform utilizing a novel ultra-sensitive method for the detection of proteins using nucleic acid labeled. Deal value -- $10.1m, of which $3.1m is cash and the balance IRIS stock. 2006-04-04T00:00:00 0 10.1 0 0 0 740 Diagnostics Molecular Devices Corporation (NASDAQ: MDCC) a supplier of hig-performance bioanalytical measurement systems that accelerate and improves drug discovery. Laser Capture Microdissection-related business of Arcturus Bioscience the manufacturer of LCM, which allows researchers to visually and selectively excise individual cells from heterogeneous tissue for analysis. Expands Molecular Devices' life sciences portfolio by adding enabling tools for cellular analysis. Deal price -- $10m cash. 2006-04-04T00:00:00 0 10 0 0 285 Biopharmaceuticals SurModics, Inc. (SRDX) a provider of surface modification and drug delivery technologies to the medical device industry. InnoRx, Inc. a drug delivery company. Extends SurMeodics reach into ophthalmology segments. Transaction value about $10 million. 2005-01-19T00:00:00 0 10 175 Medical Devices dj Orthopedics, Inc. (DJO) a manufacturer of regeneration products for non-operative orthopedic and spine markets. Orthopedics Soft Goods business of Encore Medical Corporation a manufacturer of orthopedic implants. Strengthens DJ's domestic rehabilitation business and adds substance to the soft goods franchise, adds complementary products (i.e. safety restraints) and provides national supply contracts. Purchase price was $10 million cash, or about 1x sales. Estimates add incremental annualized net revenue to dj Orthopedics of approximately $10 to $12 million. 2005-08-11T00:00:00 0 10 10 121 Diagnostics Qiagen N.V. (Netherlands) a provider of pre-analytical sample preparation products enabling genetic and protein analysis. Nextal Biotechnology (Montreal) a provider of sample preparation tools that make protein crystallization more accessible. Creates synergies with existing technologies, expanding QIAGEN's portfolio. Transaction value of $9.7 million plus possible milestone payments possible totaling $4.5 million. Nextel's sales about $3 million. 2005-06-30T00:00:00 0 9.7 668 Medical Devices Plethora Solutions Holdings plc (AIM:PLE) a U.K. based specialty pharmaceutical company focused on urological disease. Timm Medical Technologies, Inc. a subsidiary of Endocare, Inc. (OTCBB:ENDO) and a manufacturer of a vacuum assist erectile dysfunction products. Synergizes with Plethora's urologic pharmaceutical business and adds a drug free therapy. Divestiture permits Endocare to focus on tissue and tumor cryoablation. Deal value $9.5m. 2006-01-13T00:00:00 0 9.5 0 802 Diagnostics Inverness Medical Innovations, Inc. (Amex: IMA) leading global developer of advanced diagnostic devices. TechLab, Inc a privately held developer of rapid non-invasive intestinal diagnostics tests in the areas of intestinal inflammation, antibiotic associated diarrhea and parasitology. This 49% stock-for-stock acquisition provides Inverness, whose Wampole subsidiary already distributes TechLab’s products in the US, with exclusive global distribution rights to TechLab’s market leading line of enteric disease testing products, as well as future human medical diagnostic products, as Techlab’s existing global distribution relationships lapse. Inverness Medical is exploring new opportunities for its proprietary electrochemical and other technologies in a variety of professional diagnostic and consumer-oriented applications including immuno-diagnostics with a focus on women's health, cardiology and infectious disease. Inverness stock exchanged valued at about $8.6m. 2006-05-18T00:00:00 0 8.6 0 0 710 Biopharmaceuticals Healthpoint, LTD. a manufacturer of branded pharmaceuticals, OTC drugs, and medical devices for tissue management, dermatology, and surgical indications. BioSpecifics Technologies Corp. (BSTC.PK) a developer of collagenase-based products for therapeutic use. Adds to Healthpoint's topical product portfolio and permits BioSpecifics to focus on its core collagenase product development Deal terms -- $8m plus milestone payments based on sales. 2006-03-07T00:00:00 0 8 0 0 656 Diagnostics Nanogen, Inc. a developer of advanced technologies to predict, diagnose, and treat disease (PCR agents, electronic microarray platforms, rapid diagnostic kits, etc.) The rapid cardiac immunoassay test business of Spectral Diagnostics, Inc. developer of innovative technologies for comprehensive disease management. Accelerates Nanogen's growth strategy to become a leading advanced diagnostics company; complements Nanogen's Congestive Heart failure test. Total consideration for the transaction is CDN$9m, comprised of CDN$5.65m in cash and CDN$3.35m in Nanogen shares. 2006-02-07T00:00:00 0 8 777 Medical Devices Laserscope (Nasdaq: LSCP ) a leader in the development and commercialization of minimally-invasive medical devices, including medical lasers and advanced fiber-optic delivery devices. InnovaQuartz, Inc. a manufacturer of minimally invasive medical devices for mutliple medical procedures including those used in the treatment of kidney, bladder and other urinary stones. Extends Laserscope's medical disposables product line, enhances Fiber Optics R&D Capability and expands manufacturing capabilities. The acquisition is a key operational objective of savings in fiber materials costs for the main fiber optic product line, the GreenLight PV delivery device, and their R&D expertise and focus on specialty assemblies and components and rapid proto-typing will support Laserscope's existing R&D efforts to develop new, technologically superior and lower cost fiber optic medical devices. Laserscope acquired all of the capital stock of InnovaQuartz for approximately $7.5 million in cash, the assumption of approximately $1.1 million in debt and future cash payments contingent on the financial performance of IQ over approximately three years. . 2006-05-01T00:00:00 1 7.5 0 0 0 750 Medical Devices Derma Sciences, Inc. (OTCBB: DSCI) a manufacturer of wound and skin care products. The assets of Western Medical Ltd. a manufacturer of specialty medical textile dressing products utilized in long term and home care settings. Adds a complementary niche high margin wound care product line using the same distributor network and sales points. Deal price is $6.5m, with $6.5m in target business revenue (1x). 2006-04-19T00:00:00 0 6.5 6.5 0 0 785 Biopharmaceuticals Atrium Biotechnologies Inc. (TSX: ATB.sv) a manufacturer and marketer of science-based products for the cosmetics, pharmaceutical, chemical and nutrition industries. the assets of Amisol Company Ltd. a Toronto-based distributor of personal care products. Strengthens Atrium's growth strategy for their subsidiary MultiChem to be the leading supplier of personal care products in Canada. Deal price is $6m. 2006-05-02T00:00:00 1 6 0 0 2 577 Diagnostics Oxis International (OTCBB:OXIS) a producer of diagnostic enzymes, antibodies and biomarkers. BioCheck a producer of immunoassay products and biomarkers Offers a broadened portfolio of assay (antigen and antibody) test kits for medical, pharmaceutical and research applications. Increases production and marketing efficiencies. Deal price $6 million; Biocheck expected $4 million in 2005 revenues. 2005-12-08T00:00:00 0 6 4 712 Medical Services Ventiv Health Inc. (VTIV) a provider of outsourced clinical, sales, marketing, and compliance solutions for the pharmaceutical, biotechnology and life sciences industries. Synergos, Inc. a provider of clinical trials management services. Strengthens Ventiv's presence in the biotech, medical device and emerging pharmaceutical markets, adding clinical trial monitoring, regulatory affairs, medical writing and full service clinical trial management. Deal value -- $5.75m in cash and stock, plus earn-outs. 2006-03-13T00:00:00 0 5.75 665 Data Management/ Healthcare IT Captiva Software Corp. (NASDAQ:CPTV) ADP Context Inc., a part of Automatic Data Processing Inc. (NYSE:ADP) a major data processing company. ADP Context provides automated software solutions for complex medical claims processing, coding, editing and reimbursement challenges, enabling Captiva to better serve its claims processing customers and expand its reach in the healthcare insurance market. Complements Captiva's ability to process paper based medical claim. $5.2 million cash transaction, with expected incremental revenues in excess of $4 million. 2004-01-29T00:00:00 0 5.2 4.5 0 684 Medical Devices Cyberkinetics Neurotechnology Systems, Inc. (CYKN) a developer of neural stimulation technology for severe paralysis resulting from spinal cord injuries and neurological disorders. Andara Life Science Inc. a developer of programs to repair and regenerate neural tissues which were developed at the Center for Paralysis Research @ Purdue University. Adds a potentially profitable neurotechnology product line, which is subject to regulatory approval. Deal value $4.5m in stock. 2006-02-15T00:00:00 0 4.5 0 0 3 812 Biopharmaceuticals Emergis Inc. (TSX: EME) a Canadian-based information technology company in the health and financial services sectors. the pharmacy management systems business of FrontLine Solutions Inc. an automated prescription fulfillment process that provides integrated point-of-service solutions for in-store operations. Emergis increases its presence in Ontario and now provides pharmacy management systems to some 2,900 pharmacies, or approximately 40% of all pharmacies in Canada. Pharmacy management systems automate the prescription fulfillment process and provide an integrated point-of-service solution for in-store operations. Deal value is $4m. 2006-05-29T00:00:00 1 4 0 0 0 248 Medical Devices dj Orthopedics, Inc. (DJO) a manufacturer of regeneration products for non-operative orthopedic and spine markets. Superior Medical Equipment, LLC (SME) a provider of orthopedic soft goods. Superior increases dj's penetration in the New England market, as well as adding new products. Superior Superior’s annual revenues are approximately $3 million. Transaction value about $3.7 million (1.23x sales). 2005-03-14T00:00:00 0 3.7 3 697 Diagnostics Inverness Medical Innovations, Inc. (AMEX: IMA) a provider of diagnostic products for women's health and chronic disease self-management. Clondiag Chip a German developer of highly sensitive and specific diagnostic tests for rapid point-of-care applications. Expands Inverness' patent portfolio with nucleic acid probes and immunological tests for rapid point-of-care diagnostics. Inverness acquires 67.45% of Clondiag stock for Inverness shares plus $3.1m in cash and agrees to settle obligations of $10m. Inverness will acquiring remaining shares for approximately $4.9m. Additional contingent payments based on new product development milestones. 2006-03-03T00:00:00 0 3.1 0 0 654 Medical Devices Datascope Corp. (NASDAQ: DSCP) a diversified medical device company that manufactures proprietary products for interventional cardiology and radiology, cardiovascular and vascular surgery, anesthesiology, emergency medicine and critical care. CardioVations endoscopic vessel harvesting line of Ethicon, Inc. a unit of J&J. A complementary product line for Datascope. This $3.25mm deal is contingent on the Guidant/J&J deal closing. The CardioVations unit had about $13mm in sales. 2005-12-30T00:00:00 0 3 122 Diagnostics Qiagen N.V. (Netherlands) a provider of pre-analytical sample preparation products enabling genetic and protein analysis. Assets of LumiCyte, Inc. an R&D company creating sample preparation tools for protein analysis using its proprietary STS-Biochip™ technology. Creates an expanded proprietary portfolio for QIAGEN in sample preparation of proteins and peptides. Transaction value of $3 million with additional milestones of $4 million and $5 million after 18 and 30 months, respectively. See entry regarding SuNyx. 2005-08-01T00:00:00 0 3 678 Medical Devices Kyphon Inc. (Nasdaq: KYPH) develops and markets medical devices designed to restore spinal function using minimally invasive technologies. InnoSpine, Inc. a developer of proprietary technology for the diagnosis and potential treatment of axial low back pain due to disc degeneration. Extends Kyphon's spinal treatment solutions by adding a novel diagnostic method known as Functional Anesthetic Discography (FAD), which involves a single-use disposable with no capital equipment requirements. Deal value of $2.5m, with $27.5m in possible milestone payments. Terms not disclosed. 2006-01-05T00:00:00 0 2.5 0 0 10 702 Diagnostics MedMira (NASDAQ: MMIRF) a Canadian-based developer of rapid diagnostic solutions. SensorChem International a developer of new diagnostic technologies. Expands MedMira's product portfolio. Deal price -- $2.0m. 2006-02-27T00:00:00 0 2 123 Diagnostics Qiagen N.V. (Netherlands) a provider of pre-analytical sample preparation products enabling genetic and protein analysis. SuNyx GmbH (Germany) a developer of a lab-on-a-chip technology platform. Positions QIAGEN as leading provider for standardized, on-chip sample preparation in the rapidly growing field of MALDI and LC-MALDI Mass Spectrometry for protein analysis. The SuNyx deal valued under $2 million ($0.8 million cash with additional $0.8 subject to milestones). See entry regarding LumiCyte. 2005-08-01T00:00:00 0 2 681 Biopharmaceuticals Cambrex Corporation (NYSE: CBM) a diversified life sciences developer of human therapeutics. Cutanogen Corporation a privately-held biotechnology company developer of products to treat severe burns. Cutanogen's PermaDerm cultured skin complements OrCel(R), a wound healing product from Ortec International, which Cambrex expects to market upon its anticipated regulatory approval in 2006. Deal value $1.6m at closing with $4.8m in potential milestone payments. 2006-02-02T00:00:00 0 1.6 0 0 105 Diagnostics Eleckta AB a provider of advanced clinical solutions for the treatment of cancer and brain disorders. IMPAC Medical Systems, Inc.(IMPC) a leading provider of oncology management and HL7 imaging connectivity software systems. Elekta and IMPAC will be able to offer an ntegrated solution addressing wider spectrum of the cancer care process from diagnosis through treatment planning, delivery, and follow-up, including cancer registry and decision support. Enterprise value about $250mm. 2005-04-04T00:00:00 0 1 682 Distribution McKesson Corporation (NYSE:MCK) a large healthcare services and information technology company. Sterling Medical Services, LLC a national provider of medical supplies and health management services to the homecare market and a subsidiary of Coloplast A/S (Denmark). Sterling's direct-to-patient distribution to homecare patients with chronic illnesses complements McKesson's growing homecare footprint. McKesson's services include technology to monitor patients in the home, disease management programs, nurse triage services, physician-patient connectivity, online portal technology and personal emergency response systems. Terms not disclosed. 2006-02-13T00:00:00 0 0 0 13 772 Biopharmaceuticals Kendle International Inc. (NASDAQ: KNDL) a global clinical organization focused on research in the areas of oncology, CNS, analgesia/pain,inflammation, gastroenterology and cardiovascular. Latin America CRO International Clinical Research LTD. and related companies Latin America-based, an organization of drug research and development companies. Further strengthening Kendle's global clinical development capabilities in the Phase II-IV arena through new operations in Argentina, Brazil, Chile and Colombia. Kendle now offers coverage across more Latin American countries than any other CRO and builds on the company's strong base of operations in Mexico and Peru. Terms were not disclosed. 2006-04-25T00:00:00 1 0 0 0 0 765 Diagnostics Nanogen, Inc. (Nasdaq: NGEN ) developer and manufacturer of advanced diagnostic products. Amplimedical S.p.A. diagnostics division an Italian-based manufacturer of molecular diagnostic products, offering a broad range of real-time and end-point molecular diagnostic test kits, all CE marked for in vitro diagnostics. Expands Nanogen's molecular diagnostic business in Europe, based on a past five year relationship. during which time Amplimedical has been a distributor of Nanogen's NanoChip® Molecular Biology Workstation and NanoChip® 400 instrument systems in Italy. Nanogen Advanced Diagnostics, S.r.L. will be the merged company name. a wholly owned subsidiary of Amplifon (La Borsa: AMP), today announced that Nanogen will acquire the assets of Amplimedical's diagnostics division in a transaction of 8.1 million Euros consisting of 2.0 million Euros in cash and 6.1 million Euros in a promissory note convertible into Nanogen common shares. 8.1m Euro =10.095m US dollars 2.0m Euro =2.49m US dollars 6.1m Euro =7,601m US dollars 2006-04-20T00:00:00 1 0 0 0 0 763 Biopharmaceuticals Pacgen Biopharmaceuticals Corporation a developer of innovative peptide therapeutics for the prevention of infectious diseases and immune system regulations where current therapies are inadequate or ineffective. IL Therapeutics, Inc. a developer of a drug candidate ("PAC-G31P) as a therapeutic in the prevention and treatment of severe inflammatory diseases characterized with neutrophil over-recruitment. Strengthens Pacgen's capital structure and product pipeline by acquiring all outstanding shares from Western Life Sciences. Purchase price included Pacgen preferred shares, common shares and common share purchase warrants. 2006-04-17T00:00:00 1 0 0 0 0 771 Diagnostics Pelican Life Sciences a provider of products for discovery and detection focused on microbiology, molecular biology and non-commodity specialty consumables. PML Microbiologicals a provider of microbiological products to clinical and research markets. PELICAN LIFE SCIENCES SECURES $100 MI Pelican Life Sciences announced today that it has secured $100 million in private equity funding for acquisitions and development and has completed its first acquisition. Pelican Life Sciences’ mission is to facilitate life science research by providing the highest quality products for discovery and detection. Pelican’s targeted product mix includes life science reagents and specialty consumables. Focused segments include microbiology, molecular biology and non-commodity, specialty consumables. The funding commitment will be used to acquire premier companies with proven track records of providing high-quality, differentiated products to support the pharmaceutical, biotech, and academic research market. Pelican is also expecting to make significant investments in the acquired entities to support product development, streamline manufacturing operations and expand sales and marketing capabilities. With ISO 13485 certified manufacturing and distribution facilities in both the United States and Canada, PML is a leading provider of culture media and microbiological products throughout North America. 2006-04-24T00:00:00 1 0 0 0 0 790 Medical Devices Genzyme Corporation a world leading biotechnology and medical device distribution. Brennen Medical, Inc. a manufacturer and distributes medical devices specifically designed to enhance tissue repair. Expands Genzyme's offerings for hernia repair by adding the beta glucan impregnated meshes created with Brennen's use of oat beta glucan technology. Terms were not disclosed. 2006-04-12T00:00:00 0 0 0 0 0 809 Medical Services So-net M3, a Sony Communication Network Group a Japanese web-based pharmaceutical company. MDLinx a leading online provider of global, real-time health information resources for physicians and consumers. Expands So-net M3's offerings into the US market with extensive award-winning content in the research business to physicians, healthcare professionals and patients.Terms were not disclosed. 2006-05-19T00:00:00 1 0 0 0 0 803 Distribution Mölnlycke Health Care a leading provider of disposable surgical and wound care products. Regent Medical and Medlock Medical two UK-based companies, Regent, a leading surgical glove and Medlock, a niche wound care company. Significantly enhances product range and geographical expansion for Molnlycke's two divisions, Surgical and Wound Care. Reflects sales force, distribution and R&D synergies. Terms were not disclosed. 2006-04-07T00:00:00 0 0 0 0 0 801 Medical Services Media Cybernetics Inc. a developer of image informatics solutions to automate research, development, and quality control processes in life science and industry. the assets of AutoQuant specializing in image restoration, visualization, and analysis software products for life science microscopy. Enhances Media Cybernetics product line and will extend AutoQuant's deconvoltion technology farther into the life science microscopy market. AutoQuant's deconvolution algorithms have become the industry standard for quantitative microscopy. Terms were not disclosed. 2006-05-01T00:00:00 1 0 0 0 0 800 Distribution Henry Schein, Inc. (Nasdaq: HSIC) Henry Schein, Inc. (Nasdaq: HSIC) the largest provider of healthcare products and services to office-based practitioners in the combined North American and European markets. NLS Animal Health a full-service veterinary distribution business. Expands Henry Schein's veterinary footprint in the US, which along with its growing European veterinary presence, offers Henry Schein vendor partners a unique opportunity to access veterinarians on an international basis. Terms were not disclosed. 2006-04-06T00:00:00 1 0 0 0 0 799 Distribution Welch Allyn a leading manufacturer of innovative medical diagnostic and therapeutic devices, cardiac defibrillators, patient monitoring systems, and miniature precision lamps. MediAids a Malaysian-based medical products distributor. Utilize and expands on Welch Allyn's core technologies to offer medical products that are specific to the needs of caregivers in Asia and other emerging markets in the region. Provides an opportunity to build on the years of success MediAids has had selling WA products in Malaysia. WA's new Malaysian operation will enhance its' Singapore-based research and development facility that focuses on the development of technology for patient vital signs monitoring and advanced wireless technologies. Terms were not disclosed. 2006-05-03T00:00:00 1 0 0 0 0 795 Biopharmaceuticals Thermo Electron Corporation (NYSE: TMO) the world leader in analytical instruments, scientific equipment, services and software solutions for life science, drug discovery, clinical, environment and industrial laboratories. Fisher Scientific International Inc. (NYSE: FSH ) a leading provider of products and services to the scientific community. Fisher facilitates discovery by supplying researchers and clinicians in labs around the world with the tools they need. A strategic combination that creates the world's only provider of fully integrated, end-to-end solutions in the life, laboratory and health sciences industry. The new company will be named Thermo Fisher Scientific Inc. and will have complementary technology leadership in instrumentation, life science consumables, software and services. By combining these capabilities, the company will be uniquely positioned to provide integrated, end-to-end technical solutions. Accretive to earnings. Thermo expects 2007 adjusted earnings per share of the combined company to be in the range of $2.27 to $2.37, reflecting accretion of approximately 18 percent to Thermo's consensus 2007 adjusted EPS. Accelerates revenue and earnings growth. The merger accelerates revenue growth and is expected to result in a 20 percent compound annual growth rate in adjusted EPS over three years. $200 million of synergies. The transaction is expected to generate $200 million of cost and revenue-related synergies in three years. 2007 synergies are expected to be at least $75 million. 2006-05-08T00:00:00 1 0 0 0 0 780 Medical Services MedAssist Holding, Inc. a leading provider of outsourced patient eligibility, accounts receivable management, and collections services to hospitals. Twin Medical Transaction Services, Inc. an eligibility services-focused provider of healthcare revenue cycle outsourcing solutions. Expands MedAssist's geographic footprint with additional resources, geographic reach, and customer services. Terms were not disclosed. 2006-04-25T00:00:00 1 0 0 0 0 791 Medical Services Cardinal Health, Inc. (NYSE: CAH) a global company serving the health-care industry with a broad portfolio of products and services. the pharmaceutical wholesale distribution business from The F. Dohmen Co. one of the largest pharmaceutical distributors in the US serving more that 2400 independent pharmacy and retail-chain customers in Upper Midwestern, Central, Southern and Southeast States. Compliments Cardinal's existing suite of services and enhances value proposition to retail pharmacy customers and grow its business in this area with a wide range of differentiated product and service solutions. Terms were not disclosed. 2006-05-01T00:00:00 1 0 0 0 0 773 Biopharmaceuticals Abraxis BioScience, Inc. (NASDAQ: ABBI) an integrated, global biopharmaceutical company dedicated to meeting the needs of critically ill patients. Cruce Davila,manufacturing facility from Pfizer (NYSE:PFE) a Puerto Rican-based manufacturing facility with capabilities of producing European and US compliant injectable pharmaceuticals. Abraxis is now positioned to be one of the broadest injectable manufacturers of sterile injectable pharmaceuticals with capabilities of producing EU and US compliant injectable pharmaceuticals, as well as protein based biologics and metered dosed inhalers. The acquisition will provide a third manufacturing site using the company's proprietary nanoparticle albumin bound (nab™) technology to produce chemotherapeutics such as ABRAXANE® for Injectable Suspension the first commercial product based on this technology. Terms were not disclosed. 2006-04-25T00:00:00 1 0 0 0 0 789 Medical Services MMS a regional independent healthcare distributor with divisions in nursing homes, hospitals, physician practices, government facilities, specialty products, home care, pharmaceutical industrial business and redistribution. Henry Schein's Extended Care and Caligor Hospital Divisions (NASDAQ: HSIC) a provider of services in hospitals, nursing homes and home care dealers. Allows MMS to continue to strengthen their goal of being a regional distributor with a national presence. Terms were not disclosed. 2006-04-03T00:00:00 1 0 0 0 0 788 Medical Devices Hologic, Inc. (NASDAQ: HOLX) a leading provider of state-of-the-art diagnostic and digital imaging systems directed towards women’s health AEG Elektrofotografie GmbH a German-based manufacturer for a variety of electro-photographic processes, including copying, printing, and x-ray imaging applications. BEDFORD, Mass. (May 2, 2006) - Hologic, Inc. (NASDAQ: HOLX), a leading provider of state-of-the-art diagnostic and digital imaging systems directed towards women’s health, today announced it has acquired AEG Elektrofotografie GmbH and its group of related companies (“AEG Elektrofotografie”) for a purchase price of EUR 21 million subject to adjustment, plus a one-year earn-out of EUR 1.7 million. The purchase price consists of EUR 16,297,650 in cash and an additional 109,720 shares of Hologic Common Stock. The common stock is subject to certain lockups based on achieving an EBITDA target or if the stock price increases/decreases by a set amount. The earn-out will be payable in cash if AEG Elektrofotografie calendar year 2006 EBITDA exceeds a pre-set amount. AEG Elektrofotografie, a privately held company headquartered in Warstein, Germany, is a leading manufacturer of photoconductor materials, and is Hologic’s sole supplier of amorphous selenium photoconductor coatings employed in its Selenia full-field digital mammography detectors. AEG Elektrofotografie also develops, manufactures, and sells photoconductor materials for use in a variety of electro photographic applications, including copying and printing. AEG Elektrofotografie’s estimated revenue in calendar year 2005 was EUR 42.7 million. Hologic expects this acquisition to be accretive to earnings. With the acquisition of AEG Elektrofotografie, Hologic takes direct control over a critical step in its detector manufacturing process. Hologic and AEG Elektrofotografie had previously developed a close collaborative relationship, including in manufacturing and research and development. The combination of the companies should facilitate further manufacturing efficiencies and accelerate research and development of new detector products. “The agreement to acquire AEG Elektrofotografie is consistent with the Company’s long-term strategic plan,” said Jack Cumming, Chairman and Chief Executive Officer. “With our amorphous selenium detector technology, we are well positioned to benefit from the transition of analog to digital mammography. Bringing amorphous selenium technology in-house should allow us to more efficiently manage our supply chain, improve manufacturing margins and respond to the continued growth of Selenia and future product development requirements.” “We are pleased to ensure that our long-standing tradition of providing innovative high quality products to our customers will continue as a result of this business transaction,” said Manfred Wagner, Chairman of the Managing Board of AEG Elektrofotografie. “We are confident that Hologic along with our talented team will work collaboratively to build an even stronger platform for x-ray imaging applications.” 2006-05-02T00:00:00 1 0 0 0 0 783 Data Management/ Healthcare IT 3M Information Systems a leading provider of advanced software tools and services that help health care organizations capture, classify and manage accurate health care data. SBG GmbH a Berlin-based developer of diagnosis related groups (DRG) software for hospitals. Expands and strengthens 3M's product portfolio in coding, DRG determination and medical documentation. Terms undislcosed; subject to customary closing conditions. 2006-05-02T00:00:00 0 0 0 0 0 779 Data Management/ Healthcare IT The Thomson Corporation (NYSE: TOC; TSX: TOC) a global provider of integrated information solutions to business and professional customers. Centre for Medicines Research International a UK-based company that provides pharmaceutical R&D performance metrics. Expands Thomson's offerings to the global pharmaceutical industry by adding R&D performance metrics. Thomson will also expand CMR's product offerings and consulting services and enable CMR to reach smaller pharma/biotechs and CROs. Terms were not disclosed. 2006-04-25T00:00:00 1 0 0 0 0 775 Biopharmaceuticals OTN a leading specialty pharmaceutical services company and the second largest distributor of products and services to the community oncology market. The Oncology Distribution business of Cardinal Health (NYSE: CAH) a global company serving the health care industry with a broad porfolio of products and services. Increases OTN's customers to more than 4,000 specialty practices nationwide, including oncology and rheumatology practices. Broadens OTN's expertise and ability to deliver the services needed to ensure specialty drugs, coordinated reimbursement and clinical services. Cardinal Health will participate in this market as a minority owner in OTN’s parent company, Oncology Holdings, Inc. Terms were not disclosed. 2006-04-27T00:00:00 1 0 0 0 0 774 Medical Services SRI International a leading independent, non-profit research and technology development organization. Quality Clinical Labs a commercial laboratory,specializing in clinical hematology and chemistry evaluations. Expanding on a relationship with QCL, the acquisiton extends SRI's already comprehensive services by adding QCL's clinical pathology work. Terms were not disclosed. 2006-04-24T00:00:00 1 0 0 0 0 793 Medical Devices ETHICON, INC. a Johnson & Johnson company, develops and markets surgical products for use in general surgery, wound management, women's health and cardiovascular surgery. Vascular Control Systems, Inc. a developer of medical devices to treat fibroids and to control bleeding in obstetric and gynecologic applications. Strengthens Ethicon's gynecology business by adding Vascular's technology for uterine artery occlusion treatment that offers a minimally-invasive alternative to current therapies. Terms were not disclosed. 2006-05-09T00:00:00 1 0 0 0 0 766 Biopharmaceuticals Pfizer, Inc.(NYSE: PFE) a global drug developer and manufacturer. Rinat Neuroscience Corporation a developer and manufacturer therapeutic proteins for the treatment of diseases and disorders of the central nervous system. Enhances Pfizer's internal research and development efforts by adding Rinat's product portfolio. Rinat is a pioneer in developing protein-based therapeutics to develop new medicines, notably for the treatment of Alzheimer's disease. Terms were not disclosed. 2006-04-06T00:00:00 1 0 0 0 0 655 Distribution MBF Healthcare Partners a private equity firm specialized in healthcare services. Medical Specialties Distributors a large supplier of infusion and bio-medical products for home care markets. MBF's principals, steeped in healthcare experience, plan to add strategic direction and capital to expand Medical Specialties. 2005-12-30T00:00:00 0 0 776 Medical Devices RITA Medical Systems, Inc. (Nasdaq: RITA) a manufacturer of RF ablation products for cancer, vascular and spinal applicatons. Biocompatibles International plc (LSE: BII ) a UK-based developer of drug-device combination products for use in oncology and cardiology. Offers emerging device-based therapies for the treatment of cancer by adding the LC bead embolization product in the United States and Canada. a publicly traded company focused solely on cancer therapies, today announced the signing of an exclusive three-year supply and distribution agreement with United Kingdom-based Biocompatibles International plc (LSE: BII ) to market its LC Bead embolization product in the United States and Canada. The product is designed as a minimally invasive treatment for hypervascular tumors. The LC Bead microspheres are injected into selected vessels to block the blood flow feeding a tumor, causing it to shrink over time, and is often used in combination with radiofrequency ablation (RFA). Embolization is commonly used to treat a number of conditions, including hepatocellular carcinoma, the most common form of primary liver cancer, and neuroendocrine tumors. "We believe the LC Bead is the technology of choice in this emerging field of medicine," said Joseph DeVivo, President and CEO of RITA Medical Systems. "This minimally invasive treatment for cancer fits closely with our existing product offerings and with our position as an outstanding medical device oncology company providing real value to doctors and their patients. Based upon our relationships within the interventional radiology community, and the potentially complementary nature of this technology with our core RFA technology, we believe our existing sales force will be able to successfully introduce this product to the U.S. market." He continued, "We are very pleased to partner with Biocompatibles, whom we believe to be a world leader in the development of micro-infusion therapies." "We believe we have found the right partner in RITA Medical for U.S. and Canadian distribution of the LC Bead," said Crispin Simon, Chief Executive of Biocompatibles International. He continued, "We share RITA's vision of device-based therapies playing an expanding role in the treatment of cancer. Our common goal is to make cancer therapy both more effective and less traumatic for patients. We chose RITA because of their intense focus on the introduction of novel medical device oncology technology and their ability to influence physicians who will ultimately drive the clinical adoption of embolization." The LC Bead is cleared for use in embolization of hypervascular tumors and arteriovenous malformations in the United States by the U.S. Food and Drug Administration (FDA). The product will be distributed by RITA from its U.S. operations center in Manchester, Georgia. "The use of embolization to treat liver cancer is very synergistic with RITA's current surgical and RFA products: where radiofrequency works by destroying the tumor from the inside out, embolization works from the outside in," said Jelle W. Kylstra, MD, Vice President and Medical Director of RITA Medical Systems. "Many patients currently receive both treatments. Where some clinicians use trans-arterial chemo-embolization (TACE) at the periphery of large tumors following RFA, others are using TACE prior to RFA as a means of obstructing blood flow into the tumor, with the goal of enhancing the speed and size of subsequent RFA." 2006-04-27T00:00:00 1 0 0 0 693 Medical Devices Best Vascular, Inc. a division of Best Medical International, created to focus on The Novoste System. Novoste Corporation (NASDAQ:NOVT) a manufacturer of The Novoste System, the only remaining vascular brachytherapy product on the market. Best Vasular was established by Best Medical for the sole purpose of focusing on the VBT product acquired from Novoste, providing this specific therapy across a wide variety of clinical applications. Terms not disclosed. 2006-03-09T00:00:00 1 0 0 0 691 Medical Services DSI Holding Company an acquiror and operator of dialysis clinics, hospitals and acute care centers. Fresenius Medical Holdings, Inc. and Renal Care Group two large operators of dialysis clinics that are merging. Funded by Centre Partners, a private equity firm, DSI is acquiring 100 dialyses clinics being divested as part of the Fresenius-Renal Care merger. Terms not disclosed. 2006-02-16T00:00:00 0 0 0 743 Biopharmaceuticals Millipore Corporation (NYSE:MIL) a leading bioprocess and bioscience products and services company. Newport Bio Systems a provider of process containers used in biopharmaceutical production. Enables Millipore to provide a more comprehensive line of disposable process containters, manifolds, and assembly systems for collecting, storing, and transferring process fluids used in biopharmaceutical manufacturing. Builds on its acquisition of NovAseptic completed last year. Terms were not disclosed. 2006-04-05T00:00:00 0 0 0 0 0 739 Dental Sybron Dental Specialties, Inc.(NYSE:SYD) a manufacturer of dental consumables and infection control products. Dental Disposables International, Inc. a manufacturer of infection prevention products. Strengthens Sybron's infection prevention business and adds brand names Allrap®, Googles™ and Slip-N-Grip® to Sybron's portfolio of products. 2006-04-03T00:00:00 1 0 0 0 0 745 Biopharmaceuticals SurModics, Inc. (NASDAQ:SRDX) a provider of surface modification and drug delivery technologies to the medical device industry. The intellectual property of Intralytix, Inc. a biotechnology company focused on production of products using bacteriophages to control bacterial pathogens in environmental, food processing and medical settings. Expands SurModics technology offerings in the drug delivery arena with the intellectual property relating to polyester-amide (PEA) biodegradable polymers, which naturally degrade in the body into amino acid components, the building blocks of proteins. Terms were not disclosed. 2006-04-05T00:00:00 1 0 0 0 0 694 Medical Devices Cardium Therapeutics, Inc.. (OTC: CDTP) a technology company focused on development, manufacture and sale of new and innovative therapeutic products for the interventional cardiology market. InnerCool Therapies, Inc. a developer of endovascular catheter systems to rapidly and controllably lower patient body temperature during surgery and intensive care. Complements Cardium's biologic approach to the treatment of cardiovascular disease. Potential future applications of InnerCool's technology include endovascular cooling for cardiac arrest, acute ischemic stroke and myocardial infarction (heart attack). Cardium will issue 2.5 million common and will assume certain outstanding liabilities ($560,000) plus transaction costs and vacation accrual). Potential milestone payment of $5 million if InnerCool sales exceed $20 million. 2005-03-09T00:00:00 0 0 0 0 746 Data Management/ Healthcare IT MedAssist, Incorporated a leading provider of outsourced patient eligibility, accounts receivable management, and collections services to hospitals. Capstone Solutions, LLC a provider of healthcare revenue cycle outsourcing solutions. Complements MedAssist's core service delivery while opening several new lines of business that will expand MedAssist's strategic commitment to its clients. Capstone's suite of services include business office operational assessments, process improvement implementation, business intelligence and database applications, and customized A/R reporting technology for a broad range of healthcare providers. MediAssist is owned in part by RoundTable Partners, a private equity firm. Terms not disclosed. 2006-04-14T00:00:00 0 0 0 0 0 658 Biopharmaceuticals Genzyme Corporation a leading biotechnology company. The adeno-associated virus technology of Avigen Inc. (NASDAQ: AVGN) a biotech developer of small molecule therapeutics for treating neurological conditions. In this $12 million cash deal (plus royalties and milestone payments), Genzyme acquires a broad gene therapy patent estate, a Phase I/II program in Parkinson's disease and a clinical collaboration in hemophilia. Recently, Genzyme also bought Genesys Inc.'s manufacturing operation for $3.2 million to support the growth of its gene-therapy programs. 2005-12-31T00:00:00 0 0 657 Data Management/ Healthcare IT Spheris, Inc. a leading global outsource provider of medical transcription technology and services. Vianeta Communications a leading developer of enterprise-wide clinical documentation software for group practices, hospitals and health systems. Enables Spheris to enhance its medical documentation solutions. Integrating Vianeta's open and scalable XML-based software into Spheris' existing transcription technology accelerates other initiatives. Terms were not disclosed. 2006-05-08T00:00:00 1 0 649 Data Management/ Healthcare IT MedLink International, Inc. (OTCBB:MLKNA.OB) a developer of networking systems for doctors and others securely communicate and to remotely access and retrieve patient records, lab results, X-Rays, CAT Scans and other pertinent patient information. CNI Medical Coding & Recovery, Inc. a reimbursement recovery firm utilizing electronic claims and other strategies. This agreement in principle enables Medlink to refer its physicians internally for their billing and recovery needs and gives Medlink access to CNI clients for the MedLink EHR and other services. 2005-12-07T00:00:00 0 0 747 Medical Devices ZOLL Medical Corporation (NASDAQ: ZOLL) a manufacturer of resuscitation devices and related software solutions. Lifecor, Inc. a manufacturer of a wearable external defibrillator system. Completes Zoll's earlier acquisition of Lifecor's technology for in-hospital use, by adding the assets and business. Zoll will assume Lifecor's outstanding debt of $5.8m plus an additional $3m owed to Zoll and liabilities of $1.3m. Additional consideration will be in the form of earn-out payments to Lifecor based upon future revenue growth of the acquired business over a five-year period. 2006-03-22T00:00:00 1 0 0 0 0 755 Medical Devices Misonix, Inc. (Nasdaq: MSON) a developer of ultrasonic medical device technology for the treatment of cancer and other health conditions UK-HIFU Limited a distributor of High Intensity Focused Ultrasound (HIFU) operations in Europe Enables Misonix to strengthen its presence in the European HIFU market and broaden the acceptance and use of HIFU-based medical devices. This transaction also provides a stronger distribution outlet for all our HIFU products in development.The Sonablate(R) 500, which is manufactured by Misonix and distributed in the UK for Misonix by UK-HIFU, has been awarded a CE mark in Europe, and has been approved by the UK's National Institute for Clinical Excellence.UK-HIFU has been marketing the Sonablate 500 in the UK for Misonix for nearly two years. Terms were not disclosed. 2006-04-10T00:00:00 1 0 0 0 0 744 Medical Devices Medical Creative Technologies, Inc. a manufacturer of minimally invasive surgical medical devices. The intellectual property of Dexterity Surgical Inc. a manufacturer of instruments and medical supplies. Adds Dexterity Protractor® and Dexterity PneumoSleeve® to MCT's minimally invasive surgery product line. Terms were not disclosed. 2006-04-04T00:00:00 0 0 0 0 0 726 Biopharmaceuticals Ranbaxy Laboratories Limited a large India-based generic drug company. The unbranded generic business of Italy-based Allen S.p.A, a division of GlaxoSmithKline a multi-national pharmaceutical manufacturer. "Fast tracks" Ranbaxy’s growth plans in Italy; complementary product portfolios and pipelines. The Italian generic market is one of the fastest growing markets in Europe. As per IMS, December, 2005, its value was approximately $420m, with an annual growth rate of 49%. Ranbaxy has a presence in 21 of the 25 EU countries and is rapidly consolidating its presence in Europe. Terms not disclosed. 2006-03-27T00:00:00 0 0 0 0 0 721 Diagnostics SunTech Medical Group Limited a manufacturer of motion-tolerant, non-invasive blood pressure monitoring products. Oakfield Instruments Limited UK-based manufacturer and distributor of gastrointestinal pressure, pH monitoring equipment and urology products. Furthers SunTech's plans to grow into a focused medical diagnostics business.The financial investment and managerial support will enable Oakfield to accelerate its existing product development plans, enhance its marketing efforts and extend its current export activities. Terms not disclosed. 2006-03-21T00:00:00 0 0 0 0 0 737 Distribution Midwest Medical Supply, Inc. one of the largest independent regional healthcare distributors. The Caligor Hospital Supply and Extended Care business of Henry Schein, Inc. a major distributor of healthcare products primarily to physicians. Gives MMS a strong presence in the northeast and continues its goal to have national distribution presence. More than doubles MMS' sales to around $340m. Deal terms not disclosed. 2006-04-03T00:00:00 0 0 0 732 Medical Devices Zimmer Holdings, Inc. (NYSE: ZMH) a leading orthopedic products manufacturer. MedTech's intellectual property for BRIGIT™ device a voice-actived device to aid surgeons during joint replacement procedures. Strengthens Zimmer's ability to aid surgeons' accuracy and efficiency. Terms not disclosed. 2006-03-22T00:00:00 0 0 709 Medical Services Grifols a Spanish company specializing in the production of biopharmaceuticals PlasmaCare, Inc. a manager of plasma collection centers. PlasmaCare's 15 plasma collection centers from PlasmaCare, located in the Mid-West and the South, will be added to the 50 plasma collection centers Grifols already has in North America. With this acquisition, Grifols will be the world's second largest supplier of plasma. Terms not disclosed. 2006-03-15T00:00:00 0 0 0 715 Data Management/ Healthcare IT Aptuit, Inc. a provider of drug development services and technologies. InfoPro Solutions Inc. a provider of multisite clinical information technology platforms. Enables Aptuit to leverage InfoPro Solutions' expertise to deploy a global, multi-customer, multi-site platform to enable clients to track drug development projects anywhere in the world in real time. InfoPro Solutions' development facility in Bangalore will provide the company with a strategic base for its informatics operations. Terms not disclosed. 2006-03-15T00:00:00 0 0 0 688 Data Management/ Healthcare IT Decision Resources, Inc. a research/advisory firm focused on pharmaceutical and healthcare industry analysis. Millennium Research Group a provider of strategic information for the medical device, pharmaceutical and biotechnology industries. Significantly expands Decision Resources' breadth of research services to include comprehensive coverage of medical devices. Terms not disclosed. 2006-02-02T00:00:00 0 0 0 706 Medical Devices Terumo Corporation a leading manufacturer of single-use medical devices, such as syringes, blood bags and IV solutions. MicroVention, Inc. a developer of catheter-based technologies for the endovascular treatment of cerebral and peripheral vascular diseases. Enables Terumo to expand into the growing worldwide market for the endovascular treatment of cerebral aneurysms. Terms not disclosed. 2006-02-28T00:00:00 0 0 0 659 Medical Devices American Medical Instruments Holdings Inc. a holding company for seven medical device companies formerly party of the Marmon Group. Point Technologies, Inc. a medical wire and tube critical component manufacturing company. Point Technologies will become the contract manufacturing division of AMIH catering to OEM medical device companies. 2005-12-22T00:00:00 0 0 703 Diagnostics OncoVista Inc. a biopharmaceutical company developing drugs for treatment of cancer and other diseases. AdnaGen a German-based developer of rapid detection technology focusing on tumor diagnosis. AdnaGen's proprietary technology improves OncoVista's ability to select patients to respond to its targeted therapies in clinical trials. Majority stake acquired. Terms were not disclosed. 2006-02-23T00:00:00 0 0 731 Biopharmaceuticals China-Biotics, Inc. (OTCBB:OTRS) Shanghai based manufacturer of probiotics products. Sinosmart Group Inc. a holding company that owns 100% of a Shanghai based producer of probiotic dietary supplements. Enables China-Bioteics to further penetrate the Chinese probiotics marketplace and capitalize on the rapidly growing demand for domestically produced, bulk probiotic additives (bacteria that exist naturally in the human body believed to be necessary for intestinal tract health). Stock deal -- approx. 16m China-biotics shares issued. 2006-03-31T00:00:00 0 0 20 8 695 Diagnostics PerkinElmer, Inc. (NYSE: PKI) a global technology leader in health sciences. The proprietary proteomics technology of Agilix Corporation a research and development company engaged in creating protein labeling tools for quantitative analysis. Brings quantitative proteomics to PerkinElmer customers in drug discovery and proteomics researc; enhances the utility of mass spectrometry, a preferred method for proteomic analysis. Terms not disclosed. 2006-03-09T00:00:00 0 0 0 0 0 666 Data Management/ Healthcare IT Picis Inc. a vendor of information systems for operating rooms and ICUs. ibex Healthdata Systems Inc. a provider of emergency department information systems. Provides a single vendor to automate related, cost-intensive hospital departments. Combined operations serve 900 hospitals and have annual revenues of $50 million. Terms not disclosed. 2004-08-04T00:00:00 0 0 0 0 664 Data Management/ Healthcare IT 3M Health Information Systems a provider of software solutions for coding, reimbursement and compliance to more than 4,000 providers. Info-X Inc. a leading provider medical coding compliance software. Strategic add-on for 3M's software application to help providers comply with regulations and mange resources. Info-X software enables providers to check local medical review policies at the point of coding and facilitates clean reimbursement claims. Terms not disclosed. 2004-08-04T00:00:00 0 0 0 0 663 Data Management/ Healthcare IT ChartOne, Inc. a large supplier of medical record management services and technology. InterTech Information Management, Inc. (dba eWebHealth) a provider of Web-based applications to expedite the secure delivery of medical records over the Internet. eWebHealth's technology will be added to ChartOne's suite, offering a more comprehensive set of solutions for electronic health information management. eWebHealth has about 250 hospital and clinic customers using its remote coding and Web-based document imaging solutions. Terms not disclosed. 2004-07-12T00:00:00 0 0 0 707 Distribution AmerisourceBergen Corporation (NYSE:ABC ) a large pharmaceutical services companies serving the United States, Canada and selected global markets. Asenda Pharmaceutical Supplies Ltd. a Canadian distributor of pharmaceuticals and other healthcare products in British Columbia and Alberta. Provides for a logical expansion of ABC's pharmaceutical distribution business in the Western Canadian provinces and continues its strategic focus on the pharmaceutical supply channel. Ascenda generated about US$172 million in revenue over the last twelve months. Terms not disclosed. 2006-03-02T00:00:00 0 0 172 0 673 Medical Devices DePuy Orthopaedics, Inc. a major manufacturer of orthopedic products and a subsidiary of Johnson & Johnson. Hand Innovations LLC a privately held manufacturer of widely used fracture fixation products for the upper extremities Provides DePuy with leading technology in the plating business, a fast growing and under-penetrated extremities segment. DePuy's worldwide sales force can better market the product lines. Terms not disclosed. 2006-01-19T00:00:00 0 0 0 762 Medical Services Crdentia Corporation (OTCBB: CRDT) a provider of healthcare staffing services. Staff Search Ltd. a provider of per diem nursing and allied medical staffing services throughout major metro areas in Texas. Significantly expands Crdentia's ability to meet the growing staffing requirements of allied health care professionals in the areas of per diem, travel nursing, international recruitment, contractual and private duty healthcare in the metro Texas areas. Terms were not disclosed. 2006-04-18T00:00:00 1 0 0 0 0 761 Medical Services ResCare, Inc. (NASDAQ/NM: RSCR) a provider of residential, training, educational and support services for people with disabilities and special needs. Armstrong Uniserve, Inc. and Armstrong Unicare, LLC a provider of in-home personal care and respite services to the elderly and individuals with developmental, intellectual, cognitive and other disabilites. Provides ResCare with a substantial presence in Washington and provides opportunity for continued growth in much needed services. Terms were not disclosed. 2006-04-18T00:00:00 1 0 28 0 0 667 Data Management/ Healthcare IT Spheris a leading global outsource provider of medical transcription technology and services. Avicis, Inc. (formerly HealthScribe) a medical transcription company. Adds 150 health facilities as customers and 18,000 medical transcriptionists (to Spheris' 3,200), enhancing market coverage and economies of scale. Accelerates the effort to a paperless digitized medical record. Terms not disclosed. 2004-12-23T00:00:00 0 0 0 760 Biopharmaceuticals Agilent Technologies, Inc. (NYSE: A) a provider of communications, electronics and life sciences technology and chemical analysis. SynPro Corporation a manufacturer of active pharmaceutical ingredients that provide related services. Enables Agilent to offer an array of value-added services including development of analytical methods and processes, stability studies, quality control and regulatory support. Terms were not disclosed. 2006-04-17T00:00:00 1 0 0 0 0 759 Diagnostics AmeriPath, Inc. a provider of anatomic pathology, dermatology and molecular diagnostic services. Rose Pathology Associates, P.C. a provider of pathology services specializing in pulmonary, breast, cytopathology and hematopathology. Enhances AmeriPath's pathology services to both hospital and outpatient practices in the Denver market. Terms were not disclosed. 2006-04-19T00:00:00 1 0 0 0 0 653 Medical Devices 3M Electronics a provider of flex circuits used in medical devices and diagnostics, printer, and cell phone applications. Siemens Ultrasound Division's flexible circuit manufacturing line a unit of Siemens AG, a large electronics conglomerate with operations in medical imaging. Expands 3M's business in the ultrasound and medical imaging markets. Flexible circuits enable the miniaturization and high-resolution imaging. 2005-12-28T00:00:00 0 0 674 Medical Services Nationwide Mutual Insurance Company a large diversified insurance and financial services company with more than $157 billion in assets. FutureHealth Corporation a provider of disease, maternity, case and utilization management services. Expands Nationwide's absence and disability management offerings, as well as enabling Nationwide to offer FutureHealth's wellness and other programs through its sizeable sales force. Terms not disclosed. 2006-01-05T00:00:00 0 0 0 736 CAMBRIDGE, UNITED KINGDOM--(MARKET WIRE)--Apr 4, 2006 -- BioWisdom Limited, a world leader in the development and application of Intelligence Networks for the pharmaceutical industry, announced today that it has acquired the bioinformatics business of LION bioscience AG ("LION"), which is based around the SRS suite of data integration products. In accordance with an agreement announced today, BioWisdom will purchase the shares of LION bioscience Ltd, and its subsidiary LION bioscience Asset Vehicle Inc. from LION for a total consideration of up to EUR 4 million. LION has established SRS as the industry standard solution for data integration, with a strong base of over 300 commercial and academic customers. BioWisdom will continue to support and develop SRS and will be contacting its customers to confirm its commitment to enhance and build the business. "The acquisition of LION's bioinformatics business is an important step in our commercial strategy aimed at creating an international healthcare intelligence brand and reflects our ambition to be the world's leader in healthcare intelligence." said Gordon Smith Baxter, CEO of BioWisdom. "We believe that the combination of the SRS product infrastructure with BioWisdom's expertise in the application of Intelligence Networks will provide a powerful new capability for customers, spanning the areas of drug discovery through to drug development and the regulatory process". ABOUT BIOWISDOM LTD BioWisdom Limited, headquartered in Cambridge, UK, creates Intelligence Networks which are used to support decision making in all areas of the healthcare industry from early stage drug discovery and clinical development through to market profiling and due diligence on new products. The BioWisdom team combines extensive experience of the pharmaceutical and biotechnology industries with proven expertise in life science software development. www.biowisdom.com. ABOUT LION AG LION bioscience AG was founded in March 1997. The company's aim via its bioinformatics business was to help life science companies increase their productivity in the R&D process. With its SRS software solutions, it took on the great challenges of making the huge amounts of available data easier to use and allows customers to make better and faster decisions about their research projects. The company is currently redefining its business model in light of the changes agreed in March 2005. LION bioscience AG is based in Heidelberg, Germany. ABOUT SRS 2006-04-04T00:00:00 1 0 0 0 756 Biopharmaceuticals Athenagen, Inc. a privately held biopharmaceutical company. Osprey Pharmaceutical Company assets which include a lead clinical compound targeting Alzheimer's disease and a large library of related analogs. The portfolio of compounds offers a number of additional opportunities for Athenagen and to combine Osprey's proprietary assets and expertise in the nACh field.Terms were not disclosed. 2006-04-12T00:00:00 1 0 0 0 0 81 Data Management/ Healthcare IT Creative Computer Applications, Inc. (AMEX:CAP) a provider of clinical information systems for hospitals, labs, pharmacies and imaging centers. StorCOMM, Inc. a privately-held developer of pictoral archive communications systems and clinical image management systems As per this stock merger agreement, CCA can offer integrated clinical and diagnostic applications to a wider customer base (more than 700 existing customer sites and a broader new markets). Combined products increase efficiencies and enhance workflows. CCA's revenue is about $7mm and market cap about $9.7mm. 2005-08-22T00:00:00 0 125 Diagnostics Virologic Inc. (VLGC) a developer of tests used in the management of cancer and diseases. Aclara BioSciences, Inc.(ACLA) a maker of drug development products. Broadens Virologic’s existing line of testing products and expands its customer base to include drug development companies. 2004-12-10T00:00:00 0 90 Data Management/ Healthcare IT McKesson Corporation a national pharmaceutical distributor and healthcare services company. Intelliclaim Incorporated a provider of claims performance technology solutions for healthcare payors. Reinforces McKesson’s position as the leading supplier of claims auditing products and services for payors. 2005-02-01T00:00:00 0 89 Data Management/ Healthcare IT Infotrieve, Inc. a provider of content software technology and information services. GenSys Software, Inc. a provider of the electronic laboratory notebook for research industries. GenSys/ELN will be the platform for Infotrieve’s life science electronic research. 2005-02-09T00:00:00 0 126 Diagnostics Agilent Life Science and Chemical Analysis, (LSCA) Business a provider of instruments, software and services to the life science and chemical analysis markets. Silicon Genetics a provider of software solutions for life science discovery. Increases Agilent LSCA’s technology/product portfolio. 2004-11-01T00:00:00 0 88 Data Management/ Healthcare IT Infocrossing, Inc. a provider of IT outsourcing and business processing solutions. Verizon Information Technologies Inc. a provider of managed care, Medicare, and Medicaid processing services. Adds healthcare claims processing and base of commercial and government accounts. 2004-10-04T00:00:00 0 87 Data Management/ Healthcare IT IDX Systems Corporation a leading provider of healthcare information systems. RealTimeImage, Ltd. a leading developer of Web-based medical specialty imaging solutions. $15.5 million purchase is part of IDX’s strategy to broaden its information technology offerings. Provides distributed access to clinical findings and associated images to healthcare institutions. 2005-04-28T00:00:00 0 127 Diagnostics Chemicon International, Inc., a division of Serologicals Corporation (SERO) a manufacturer of diagnostic products providing researches with the tools and technology necessary to study gene function in animal systems. Primogenix Inc. an embryonic stem cells technology company. Adds novel strains of mouse embryonic stems cells to Chemicons’s stem cell product portfolio. 2004-11-03T00:00:00 0 134 Distribution Medco Health Solutions, Inc. a major pharmacy benefits manager. Accredo Health, Inc. a distributor of specialty drugs and services. Adds specialty drug distribution to Medco, which was spun off from Merck in 2003. Accredo's revenues for 2004 where $1.7 billion. Transaction value about $2.2 billion. Combined company expected to generate more than $4 billion in specialty drug revenue. 2005-01-23T00:00:00 0 86 Data Management/ Healthcare IT i3 Research (an Ingenix Inc. company)organization. a specialized contract research Statprobe, Inc. a provider of comprehensive data services. Adds Midwest presence and broadens product lines and services. 2004-10-04T00:00:00 0 85 Data Management/ Healthcare IT HealthStream a $20mm provider of internet-based learning systems for healthcare providers. Data Management & Research Inc. a developer of quality surveys and data analysis. HealthStream intends to market DMR’s services to providers to help with recruiting and retention of staff. Transaction value about $10.6 million. DMR's revenue is between $4-5 million and profit between $750,000-$900,000. 2005-03-29T00:00:00 0 84 Data Management/ Healthcare IT Elsevier Science B.V. (Netherlands) a leading global healthcare and scientific publisher. MC Strategies, Inc. a US-based firm specializing in the development and delivery of online training content for the healthcare industry. Expands Elsevier's offerings in online continuing education and training. 2005-07-18T00:00:00 0 91 Data Management/ Healthcare IT McKesson Corporation a national pharmaceutical distributor and healthcare services company. Medcon Ltd. an Israeli provider of Web-based cardiac image and information management systems. McKesson adds cardiac diagnostic digital image management and archiving, procedural reporting and workflow management to its data management offerings. Medcon's 2004 revenues were $17 million. Deal value about $105 million. 2005-08-15T00:00:00 0 82 Data Management/ Healthcare IT Dendrite International Inc. (DRTE) a provider of marketing, sales, clinical and compliance solutions for the life sciences industry. BuzzeoPDMA, Inc. a provider of compliance and auditing outsourcing services to the life science industry. The combination of the two companies makes for a more complete sample and compliance management solution. 2005-01-04T00:00:00 0 114 Diagnostics Medical Home Products a provider of medical self test kits and diabetic supplies. Strictly Diabetics a provider of diabetes management, ostomy products, and wound care products. Continue MHP's expansion into the Medicare/Medicaid market. 2005-04-20T00:00:00 0 80 Data Management/ Healthcare IT Concuity Inc. a provider of revenue management solutions for the healthcare industry. Endoxy Healthcare Associates a provider of accounts receivable management and integration services. Supplements Concuity’s existing implementation and integration services. 2004-12-01T00:00:00 0 79 Data Management/ Healthcare IT Cerner Corporation (CERN) a leading provider of healthcare information technologies. Bridge Medical, Inc. a subsidiary of AmerisourceBergen Corporation. Bridge offers point-of-care barcode-enabled medication and lab specimen identification systems. Expands Cerner's presence in bar-coding market and adds to its point-of-care offerings. Pricing -- $11 million, plus limited performance-based amounts. 2005-06-16T00:00:00 0 133 Distribution McKesson Corporation a national pharmaceutical distributor and healthcare services company. Medcon Ltd. an Israeli-based global provider of web-based cardiac image and information management systems. In this $105 million merger, McKesson adds diagnostic imaging, management, archiving and workflow systems, with 300 installations (100 customers in North America), to its other information technology offerings. Adds to McKesson's enterprise imaging and electronic medical record solutions, with a cardiac focus. 2005-06-17T00:00:00 0 128 Distribution Compex Technologies, Inc. a leading mfger and distributor of electrical nerve and muscle stimulation products for pain management, rehab and sports medicine. SpectraBrace, Ltd. a physician office based DME distributor specializing in the orthopedic market. Strengthens Compex's position as a leading distributor of home-use devices for pain management and rehab and provides a growth platform to pursue orthopedic markets. Price -- $3.65 million; SpectraBrace's sales about $4 million. 2005-06-27T00:00:00 0 129 Distribution Fisher Scientific International, Inc. a leading wholesale distributor of scientific equipment and instruments. McKesson BioServices, Inc. a leader in managing biological specimens and clinical-trial materials. The $60 million cash transaction broadens Fisher’s offering of clinical-trial services. McKesson BioService’s 2004 revenue was $50 million. 2005-06-09T00:00:00 0 77 Data Management/ Healthcare IT BTC Worldwide a Canadian provider of medical records coding, document conversion and consulting services. Coding Connection Inc. a provider of medical coding services. Both companies employ medical coders working from home. Deal enables BTC to expand within the U.S. and offer its expertise to a wider customer base. 2004-10-27T00:00:00 0 130 Distribution Henry Schein, Inc. (HSIC) a leading distributor of healthcare products and services to office-based practitioners. Ash Temple Ltd a Canadian dental distributor. A synergistic acquisition that doubles Schein's 100-person sales force in Canada. Terms were not disclosed, but Ash Temple generates revenues in excess of $100 million. 2005-01-11T00:00:00 0 237 Medical Devices WorldHeart Corporation a developer of implantable ventricular assist devices (VADs). MedQuest Products, Inc. a development stage medical device company focusing on next-generation ventricular assist devices. Adds an advanced rotary pump to WorldHeart’s VAD platform. 2005-08-02T00:00:00 0 236 Medical Devices West Pharmaceutical Services, Inc. (WST) a manufacturer of components and systems for injectable drug delivery. Medimop Medical Projects, Ltd (Israel) a developer of disposable medical devices for the mixing, transfer, reconstitution and administration of injectable drugs. Enhances West's position in the growing drug reconstitution and injectable markets. West purchased 90% of Medimop's shares for $36 million cash. 2005-08-02T00:00:00 0 235 Medical Devices W.L. Gore & Associates Inc. a manufacturer of products for electronics, industrial, fabrics and medical markets. ArteriA Medical Science a manufacturer of stroke diagnosis, prevention, and treatment products. Expands the Company’s endovascular interventional product portfolio into neuro-interventional applications. Terms not disclosed. 2004-11-22T00:00:00 0 132 Distribution McKesson Corporation a national pharmaceutical distributor and healthcare services company. D & K Healthcare Resources a regional pharmaceutical distributor to independent and regional pharmacies. Gives McKesson more clout against rivals Cardinal and Amerisource, particularly in the midwest and south. D&K's 2004 revenues were about $2.5 billion, deal value about $207 million. 2005-07-11T00:00:00 0 233 Medical Devices Viasys Healthcare Inc. (VAS) a provider of respiratory, neurology, medical disposable and orthopedic products. Micro Medical Ltd. a U.K. based manufacturer of hand-held and desk top devices for respiratory measurements. Viasys now owns a number of respiratory products geared toward physician’s office practices and primary care. Micro’s posted revenues of $16 million for 2004. Transaction value about $40 million. 2005-03-15T00:00:00 0 232 Medical Devices Varian, Inc, (VARI) a supplier of scientific instruments, vacuum technologies and specialized contract electronics manufacturing services. Magnex Scientific Ltd. a manufacturer of magnetic resonance (MR) imaging magnets. Will help advance the company’s drive into MR imaging and growth in the areas of pharmaceutical and medical research. Transaction value about $32 million. 2004-11-04T00:00:00 0 83 Data Management/ Healthcare IT Ebsco Publishing, Inc. a provider of healthcare information journals abd subscription services. HealthGate Data Corporation a provider of evidence-based support tools to help healthcare providers and payors improve quality of care, reduce risk, and reduce prices. Acquires substantially all the assets of HealthGate's patient content repository for $8.1 million 2005-05-11T00:00:00 0 138 Distribution VWR International a major distributor of laboratory and scientific supplies. AGB Scientific (Ireland) a supplier of laboratory instruments and equipment. Enhances VWR’s ability to serve customers both in Europe. 2005-04-01T00:00:00 0 107 Diagnostics GeneOhm Sciences, Inc. a developer of electrochemical nucleic acid detection systems. Infectio Diagnostic (IDI), Inc. (Quebec) a provider of molecular diagnostic systems for infectious diseases. This merger brings together related molecular diagnostic capabilities, adding economies of scale, R&D capacity, and other synergies. Terms not disclosed. 2004-10-21T00:00:00 0 106 Diagnostics Evotec Technologies GmbH a German supplier of innovative technologies for life sciences and pharmaceutical drug discovery. Carl Zeiss Group an international manufacturer of life science instrumentation and optical products, divesting its uHTS (high throughput screening) business. The Zeiss uHTS product line is a natural complement to Evotec's EVOscreen® system and Clarina II and Opera™ readers that are used to confocally measure biochemical and cellular assays, respectively. Also synergizes with Evotec's reagent and disposable lines, sold to same customer base. 2005-05-09T00:00:00 0 116 Diagnostics Olympus Corporation a medical technology company with in interests in optics, instruments, diagnostics and lab automation. Advalytix AG (Germany). a producer of microfluidic products for in vitro diagnostics. Positions Olympus at forefront of leading edge diagnostics and life science developments. 2005-07-26T00:00:00 0 104 Diagnostics Clinical Data, Inc. a provider of lab and blood chemistry products to the physician office, laboratory and small hospital markets. Genaissance Pharmaceuticals, Inc. a developer of DNA-based diagnostic and therapeutic products. In this $56 million all-stock transaction, Clinical Data will enter the molecular diagnostic market with pharmacogenomic CNS and cardiac diagnostic tests. Strengthens CDI's theranostics offerings (using diagnostics to guide pharmaceutical therapies). 2005-06-21T00:00:00 0 140 Medical Devices Advance Medical Optics, Inc. a developer and manufacturer of ophthalmic surgical and eye care products. VISX, Inc. a designer and developer of technologies and systems for laser vision correction. Two complementary companies which when combined will be better positioned to serve the global vision care industry while experiencing significant cost savings and operating efficiencies. Transaction value about $1.3 billion. 2004-11-09T00:00:00 0 117 Diagnostics Philips Medical Systems a developer and manufacturer of patient monitoring systems and medical diagnostic imaging and monitoring equipment. Stentor, Inc. a provider of picture archiving and communication systems technology used for storing, managing and distributing digital radiology images. Strengthens Philips' position in the Healthcare IT market by offering an integrated portfolio, adding PACS. Transaction valued at $280 million in cash. Expected 2005 sales to grow to $50 million. 2005-08-05T00:00:00 0 102 Diagnostics Agilent Technology Inc. (A) a communications, electronics, life sciences, and chemical analysis company. Scientific Software, Inc. a provider of chromatographic data systems and informatics. Enhances Agilent's information systems for life science and chemical laboratories. SSI reported $18 million in sales for 2004. 2005-05-27T00:00:00 0 18 101 Diagnostics Agilent Technology Inc. (A) a communications, electronics, life sciences, and chemical analysis company. Computational Biology Corp. a biotech pioneer in microarray-based techniques for understanding gene regulation in disease. Agilent attains access to important intellectual property that will enable the company to provide microarray solutions for disease research, drug discovery and development. 2005-01-05T00:00:00 0 131 Distribution Jackson Products, Inc. a manufacturer and distributor of personal and highway safety products. Olympic Optical a distributor of eyewear and hearing protection products. Asset purchase includes license to use Smith & Wesson's mark on certain safety items. Jackson increases eyewear and personal safety lines. Revenues of about $12 million. 2005-06-11T00:00:00 0 118 Diagnostics QIAGEN N.V. a provider of pre-analytical sample preparation products enabling genetic and protein analysis. Artus GmbH a provider of PCR molecular diagnostic tests. QIAGEN will acquire over 60 assays as well as a number of viral and bacterial pathogens. Expected to add $15 million in net sales. 2005-05-31T00:00:00 0 15 139 Distribution Henry Schein, Inc. (HSIC) a leading distributor of healthcare products and services to office-based practitioners. Barton-Cyker Dental Supply, Inc. a regional distributor of dental products. This acquisition augments Henry Schein’s dental distribution network in the Northeast. 2004-11-18T00:00:00 0 98 Data Management/ Healthcare IT Tripos, Inc. (Nasdaq:TRPS) a bioinformatics software and consulting company. Optive Research, Inc. a software developer for computer-assisted molecular discovery. Expands Tripos’s offerings enabling its customers to accelerate commercialization of drugs and chemical compounds Transaction value about $8 million. 2005-01-05T00:00:00 0 119 Diagnostics QIAGEN N.V. a provider of pre-analytical sample preparation products enabling genetic and protein analysis. Tianwei Times (China) a manufacturer of nucleic acid sample preparation consummables for the China market. Expands QIAGEN's position in China, adding distribution, marketing, R&D and production. $2.0 million cash plus $2.0 million in potential earnouts. 2005-05-31T00:00:00 0 135 Distribution One Equity Partners LLC a private equity group. Bristol-Myers Squibb Company (BMY) a global manufacturer of pharmaceuticals and other healthcare-related products. Divesture of a non-core asset. BMY sells the Oncology Therapeutics Network, a specialty distributor of pharmaceuticals to office-based oncologists. 2004-12-14T00:00:00 0 136 Distribution Owens & Minor Inc. (OMI) a major distributor of medical and surgical supplies. Access Diabetic Supply, LLC a distributor of diabetic products. Adds blood glucose monitor devices and other diabetic lines. $32 million in sales. 2005-02-01T00:00:00 0 115 Diagnostics Nanogen, Inc. a developer of in-vitro diagnostics products to diagnose and treat diseases. Epoch Biosciences, Inc. a developer of products for the genomics and molecular diagnostics fields. Increases revenues to facilitate growth into genetic and proteomic diagnostic markets. 2004-10-22T00:00:00 0 142 Medical Devices Biolase Technology, Inc. (BLTI) a manufacturer of lasers and related products, for dental procedures. Diodem, LLC a dental technology company. 8 synergetic patents. Transaction value about $10 million. 2005-01-26T00:00:00 0 99 Dental Sybron Dental Specialties, Inc a manufacturer of dental consumables and infection control products. Innova LifeSciences Corporation a producer of dental implant systems. Sybron's cash tender offer completed. The deal enables Sybron to enter the rapidly growing dental implant market. Transaction value about $60 million. 2004-10-15T00:00:00 0 143 Medical Devices C.R. Bard, Inc. (BCR) a manufacturer of vascular, urological and surgical products. Genyx Medical Inc. a manufacturer of implantable bulking products for the treatment of stress related urinary incontinence. Genyx product line augments Bard’s existing line of continence products. Transaction value about $60 million. 2005-01-12T00:00:00 0 144 Medical Devices Medtronic, Inc. (MDT) a major manufacturer of cardiovascular and other devices. Wound Healing of Oklahoma, Inc. a developer of novel polymer technologies targeting the medical industry. Acquired the intellectual property for the investigational Cell Plant(TM) Aqueous Stent, which will allow Medtronic to evaluate a new generation of glaucoma treatment devices. 2004-11-11T00:00:00 0 97 Data Management/ Healthcare IT CareMedic Systems Inc. a provider of revenue management and regulatory compliance applications for the healthcare industry. Omega Health Systems Inc. a provider of IT solutions for the healthcare industry. Expands CareMedic’s existing product lines and integration services. 2004-12-06T00:00:00 0 145 Medical Devices Memry Corporation (MRY) a manufacturer of Nitinol components for the medical device industry. Putnam Plastic Corporation a specialty polymer-extrusion company serving the medical industry. Adds complementary products and services focused on the medical components and sub systems in transcatheter applications. Transaction value about $26 million. 2004-11-09T00:00:00 0 96 Data Management/ Healthcare IT VNU (the Netherlands) a provider of consumer, marketing and media information and analysis. IMS Health a provider of information and consulting for the pharmaceutical and healthcare industries. Results in a company providing market intelligence to three major industries: consumer packaged goods, healthcare, and media and entertainment. The merger will also accelerate the development of advisory and consulting capabilities. Merger value about $7.0 billion on pro forma combined revenues of about $5.6 billion. 2005-07-11T00:00:00 0 137 Distribution Priority Healthcare Corporation a national specialty pharmacy and distributor of disease treatment therapies. SpectraCare, Inc. a specialty infusion pharmacy. Expands Priority's specialty infusion business. Spectra's revenue is about $32 million. 2005-05-31T00:00:00 0 120 Diagnostics Qiagen N.V. (Netherlands) a provider of pre-analytical sample preparation products enabling genetic and protein analysis. RNAture a company focusing on mRNA isolation products. Qiagen acquired, from Hitachi Chemical Research Center, Inc., the world-wide exclusive rights and licenses to manufacture and market RNAture’s nucleic acid isolation products from. 2005-05-02T00:00:00 0 93 Data Management/ Healthcare IT Phase Forward (PFWD) a leading provider of integrated data management software for clinical trials and drug safety. Lincoln Technologies a provider of products and services for strategic pharmacovigilance, clinical trial safety signal detection, and applied data standards. In this all-cash transaction valued at $11 million (plus up to an additional $6 million in milestone payments), Phase Forward adds regulatory expertise and drug safety information technologies to its product line. Lincoln's revenues are about $4.5mm and it's profitable. Lincoln adds major new customers to Phase Forward -- Department of Defense and NIH; there are several customers currently served by both. The agreement is subject to several conditions. 2005-08-16T00:00:00 0 94 Data Management/ Healthcare IT Proxima, Inc. an internet consulting firm and portfolio company of Gores Technology Group. Daou Systems, Inc. (OTCBB:DAOU) a provider of information technology consulting services to healthcare organizations. Fortifies Proxicom's IT offerings. Transaction value about $21 million. 2005-08-11T00:00:00 0 95 Data Management/ Healthcare IT Varian Medical Systems, Inc., (NYSE:VAR) a manufacturer of integrated cancer therapy systems. Sigma Micro Informatique Conseil a supplier of information management software for radiation oncology and medical oncology in cancer clinics and hospitals In France and other European nations. Enables Varian to provide information management technology to Europe. Transaction value about $13 million, revenues under $7 million. 2005-01-17T00:00:00 0 141 Medical Devices ArthroCare Corp. (Nasdaq:ARTC) a manufacturer of coblation (ablation) technology products to dissolve targeted soft tissue. Opus Medical, Inc. a manufacturer and marketer of soft tissue-to-bone and tissue-to-tissue repair systems. Expands ArthroCare’s sports medicine product portfolio and will increase the revenues for it’s rotator cuff repair procedures. Transaction value about $130 million. 2004-11-15T00:00:00 0 108 Diagnostics Gen-Probe (GPRO) a manufacturer of nucleic acid testing. Corixa (CRXA) a biopharmaceutical company developing vaccine adjuvant and immunology based products. Gen-Probe licenses from Corixa rights to develop molecular diagnostic tests for potential markers of Genitourinary and other cancers. This agreement with Corixa is a significant step forward in Gen-Probes long-term stratergy to become a leader in cancer diagnostics. 2005-01-05T00:00:00 0 34 Biopharmaceuticals Manhattan Pharmaceuticals, Inc. (OTCBB:MHTT) a development stage pharmaceutical company. Tarpan Therapeutics, Inc. a pharmaceutical company developing dermatological therapeutics. Gives Manhattan rights to three key therapeutic products. 2005-01-05T00:00:00 0 23 Biopharmaceuticals Charles River Laboratories International, Inc. (CRL) a solutions provider for drug discovery and development. Inveresk Research Group, Inc. a contract research organization. Provides access to larger share of pre-clinical and clinical drug development market businesses. Transaction value of about $1.5 billion. 2004-10-20T00:00:00 0 146 Medical Devices Meridian Bioscience, Inc. (VIVO) a manufacturer of diagnostic test kits, purified reagents and related products. O.E.M. Concepts, Inc. a manufacturer of specialized biological products for the diagnostic, pharmaceutical and research markets. Adds key capabilities and revenues to Meridian’s life science business. Announced signing of letter of intent. 2004-11-10T00:00:00 0 26 Biopharmaceuticals Genzyme Corporation (GENZ) a global biotechnology company. Ilex Oncology, Inc. (Nasdaq: ILXO) an oncology drug development company. Expands Genzyme’s oncology drug portfolio and strengthens its R&D capabilities. Transaction value about $1 billion. 2004-12-21T00:00:00 0 28 Biopharmaceuticals Genzyme Corporation (GENZ) a global biotechnology company. Bone Care International, Inc. a company focused on discovery, development and distribution of vitamin D-hormone therapies to treat various disease states. Strengthens and expands Genzyme's renal business accelerating commercial entry into earlier stages of chronic kidney disease. Cash acquisition valued at approximately $600 million, net of Bone Care's cash of $119 million. 2005-07-01T00:00:00 0 29 Biopharmaceuticals GlaxoSmithKline PLC a major pharmaceutical company. Corixa Corporation a developer of products to regulate immunity. GSK acquires all scientific programs, assets and related rights to Corixa’s immunity products including the Hamilton, MT Manufacturing facility. Transaction value $300 million. 2005-04-01T00:00:00 0 30 Biopharmaceuticals Groupe NovaSep SAS a provider of drug discovery outsourcing services to pharmaceutical companies. Dynamic Synthesis (sub. of Rockwood Specialties Group, Inc.) a provider of customized synthesis manufacturing solutions. Adds additional pharmaceutical development technology. 2004-10-20T00:00:00 0 31 Biopharmaceuticals Guilford Pharmaceuticals Inc. (GLFD) a drug development company. ProQuest Pharmaceuticals Inc. a privately-owned biopharma company. Through the acquisition Guilford obtains rights to Aquavan Injection, a sedative/hypnotic that is currently in Phase III clinical testing. Transaction value about $7 million. 2004-12-02T00:00:00 0 43 Biopharmaceuticals QLT Inc. a biopharmaceutical company focused on ophthalmology, oncology, dermatology and urology. Atrix Laboratories, Inc. . a specialty pharmaceutical company focused on advanced drug delivery for oncological, dermatological, and urological conditions. Broadens the combined companies’ product portfolio in core therapeutic areas. 2004-11-19T00:00:00 0 33 Biopharmaceuticals Kyorin Pharmaceuticals Co. Ltd. (TSE: 4560) a Japanese drug manufacturer. ActivX Biociences a biotechnology company focused on advanced proteomic technologies. Cumulates two companies that have been working together to discover drug candidates targeting Type II Diabetes. Transaction value about $24 million. 2004-12-03T00:00:00 0 20 Biopharmaceuticals Cambrex France SARL (unit of Cambrex Corporation) a provider of biopharmaceutical therapeutic products. Genolife SA a producer of microbial detection products. Reduces diagnostic costs and diagnostic cycle times; leverages Cambrex's endotoxin detection sales force. Transaction value about $6 million. 2004-10-20T00:00:00 0 35 Biopharmaceuticals Millipore Corporation (MIL) a leading bioprocess and bioscience products and services company,. NovAseptic AB (Sweden) a provider of aseptic processing applications for biotech and pharmaceutical manufacturers. Expands Millipore's product offering to biotech and pharmaceutical sectors. Millipore purchased more than 90% of shares in a $91 million cash transaction. 2005-08-09T00:00:00 0 36 Biopharmaceuticals Nektar Therapeutics(NKTR) a developer of drug delivery technologies. Aerogen, Inc. (AEGN.PK) a specialty pharmaceutical manufacturer of pulmonary drug delivery products. Broadens Nektar's capabilities by adding inhaleable liquid drug technology. Transaction valued at $32 million. Areogen's revenues are about $8 million. 2005-08-15T00:00:00 0 37 Biopharmaceuticals Novartis AG (NVS) a developer and manufacturer of pharmaceuticals and nutritional products. OTC Brand Portfolio of Bristol-Myers-Squibb Company a major producer of pharmaceuticals and other healthcare related products. Novartis acquires the rights to BMS' North American OTC brand portfolio for approximately $660 million ($258 million in sales). Gives Novartis entre into the US adult analgesic market (the largest OTC market with US sales in 2004 estimated at $2 billion). Other acquired brands are No-Doz, Comtrex, and Mineral Ice. The transaction enables BMS to focus on prescription drugs and invest in research and development. 2005-07-20T00:00:00 0 38 Biopharmaceuticals Omnicare, Inc.(OCR) a provider of professional pharmaceuticals and related services to elderly care facilities. Clinimetrics Research Associates, Inc. a clinical research organization. This acquisition will supplement Omnicare’s CRO services to earlier stage biotech and pharmaceutical companies and provide additional locations in North America and Australia. 2004-12-14T00:00:00 0 39 Biopharmaceuticals Ortho-McNeil Pharmaceuticals, Inc. (a Johnson & Johnson subsidiary) a global manufacturer pharmaceuticals, services and healthcare information. Peninsula Pharmaceuticals, Inc. privately-held biopharmaceutical company focused on developing antibiotics to treat life-threatening infections. Through the acquisition J&J will own Peninsula’s lead product, doripenem, a broad-spectrum antibiotic. Transaction value about $245 million. Doripenem received Fast Track designation from the U.S. Food and Drug Administration (FDA) for the treatment of nosocomial pneumonia, including ventilator-associated pneumonia (VAP). 2005-07-11T00:00:00 0 40 Biopharmaceuticals OSI Pharmaceuticals, Inc. (NASDAQ:OSIP) a pharmaceutical company specializing in diabetes and cancer drugs. Eyetech Pharmaceuticals, Inc. (NASDAQ:EYET) a developer of therapeutics to treat eye diseases. Creates a biopharmaceutical company with $600 million in projected 2006 revenue, adding to, and diversifying, OSI's oncology and diabetes specialties. Deal value about $935 million. Eyetech's revenues are about $116 million, with operating losses. 2005-08-21T00:00:00 0 41 Biopharmaceuticals Pall Corporation (PLL) a manufacturer of filtration and purification products. BioSpera Process Division of Ciphergen Biosystems, Inc. a developer of chromatography sorbents. Adds a broad range of chromatography chemistries, which compliment Pall’s market position in drug discovery and protein purification. 2004-10-28T00:00:00 0 25 Biopharmaceuticals Genzyme Corporation (GENZ) a global biotechnology company. Wyeth Pharmaceuticals (NYSE:WYE) a global pharmaceutical and health care products company. Genzyme acquired the sale and marketing rights to Synvisc®, in the U.S. and five European countries. Synvisc® relieves the pain knee osteoarthritis, with 2004 estimated worldwide end-user sales of $240 million. 2004-11-04T00:00:00 0 32 Biopharmaceuticals Invitrogen Corporation, (Nasdaq: IVGN) a provider of technologies for disease, drug discovery and commercial bioproduction. BioSource International (BIOI) a provider of products and services supporting biomedical research by producing animal- or human-based nucleic acids and proteins. Broadens Invitrogen's collection of protein and primary antibody products which were added through the prior acquisitions of Zymed Labs and Caltag Labs. Expands Invitrogen's offerings in kinase and cytokine assay technologies for research applications and provides entre into new markets: immunology, oncology and neurodegenerative disease. The transaction value about $130 million. BioSource's revenues were $47.3 million and EBITDA $4.6 million 2005-07-26T00:00:00 0 12 Biopharmaceuticals Warburg Pincus a leading private equity firm. West Pharmaceuticals Services, Inc. (WST) a manufacturer of components and systems for injectable drug delivery, West will now have the funding to expand its drug delivery platform. Transaction value about $7 million, plus $9 million in contingent payments and a $40 million investment. 2005-01-20T00:00:00 0 2 Medical Devices Arizant Inc. a manufacturer of fluid and patient warming products. Now owned by Citigroup Venture Capital Equity Group. Actamed a U.K. distributor of temperature warming products. Actamed is Arizant's U.K. distributor. Purchase of 75% of the equity not already owned by Arizant. Terms not disclosed. 2005-07-05T00:00:00 0 3 Biopharmaceuticals Adams Respiratory Therapeutics, Inc. (ARXT) a manufacturer of prescription respiratory medications. Cornerstone BioPharma, Inc. a manufacturer of prescription and OTC drugs. Cornerstone will transfer the Humibid product line to Adams, and in return Adams will transfer their AlleRx line to Cornerstone. This transaction will adds to Adams portfolio of prescription drugs. 2005-02-15T00:00:00 0 4 Biopharmaceuticals Aeterna Zentaris Inc. (AEZS) a Canadian based biopharmaceutical company focused on the development of endocrine and oncology therapy. Artium Biotechnologies Inc. a manufacturer of value-added products and solutions for cosmetics, pharmaceuticals, chemical and nutritional industries. Increases Aeterna’s presence in the North American market for active ingredients and specialty chemicals. Transaction value about $23.8 million. 2005-01-25T00:00:00 0 2 5 Biopharmaceuticals Arpida Ltd. a Swiss-based anti-infective company. Combio A/S (Denmark) a producer of innovative chemistry technologies. Provides greater chemistry capabilities for antibiotic drug development. 2004-10-15T00:00:00 0 6 Biopharmaceuticals Bain Capital Partners,DLJ Merchant Banking, J.P. Morgan Partners and Thomas H. Lee Partners private investment groups. Warner Chilcott a specialty pharmaceutical company. Provides Warner Chilcott with significant funding to grow in woman’s healthcare and dermatology markets. Transaction value about $3.1 billion. 2005-01-19T00:00:00 0 7 Biopharmaceuticals Epimmune Inc. a developer of vaccines for cancer and infectious diseases. IDM S.A. (Immuno-Design Molecules) a biopharmaceutical company specializing in immunotherapy for the treatment of cancer. The newly formed company will focus on the development of seven product candidates in clinical development for cancer and infectious diseases. The combination increases visibility in the market. 2005-03-16T00:00:00 0 8 Biopharmaceuticals MorphoSys AG (Frankfurt Stock Exchange MOR) a developer of technology aiding in the production of synthetic antibodies. Biogenesis Ltd. (U.K.) and Biogenesis Inc. (U.S.) manufacturers of antibodies for the life science research community. Establishes MorphoSys as one of the top five European suppliers of antibodies, as well as providing it access to new antibody technology. 2005-01-20T00:00:00 0 9 Biopharmaceuticals Pfizer Inc. (PFE) a global drug developer and manufacturer. Idun Pharmaceuticals Inc. a biopharmaceutical company focused on the discovery and development of therapies to control apoptosis, (cell death). Augment's Pfizer's R&D. Pfizer can advance Idun's caspases-oriented pipeline through development and commercialization, providing a platform to treat liver damage and other diseases. 2005-02-24T00:00:00 0 259 Medical Devices St. Jude Medical, Inc. (STJ) a major cardiovascular products manufacturer. Velocimed, LLC a maker of specialty interventional cardiology devices. In this $74 million cash purchase (plus milestone payments), St. Jude acquires a proprietary patent foramen ovalue (PFO) closure system to seal defects in the septal wall between the right and left atria. 2005-04-07T00:00:00 0 11 Biopharmaceuticals Sigma-Aldrich Corporation (SIAL) a life science and high tech company. JRH Biosciences, Inc. a supplier of cell culture and sera products to the biopharmaceutical industry. Strengthens Sigma-Aldrich‘s ability to supply its customers with cell culture products. Transaction value about $370 million, JRH’s sales are $150 million (2.5 x sales). 2005-01-18T00:00:00 0 22 Biopharmaceuticals Cerberus Capital Management and Ampersand Ventures two private equity groups. Bayer AG (BAYG:DE) a global pharmaceutical and chemical company. Divesture of a non-core asset -- Bayer's blood products business. Part of Bayer's realignment. Transaction value about $590 million. 2004-12-13T00:00:00 0 13 Biopharmaceuticals LAM Pharmaceutical, Corp. a manufacturer of wound healing and transdermal drug delivery systems. New World Kellerton a pharmaceutical company based in China. LAM obtains new drugs and a GMP Chinese plant. Transaction value about $14 million (mostly in LAM stock). 2005-01-11T00:00:00 0 14 Biopharmaceuticals Tanox, Inc. (TNOX) a biotechnology company specializing in biotherapeuitcs based on monoclonal antibody technology. Sunol Tissue factor antagonist program, a division of Sonol Molecular Corporation a developer of anti-tissue factor monoclonal antibodies and related technologies. Tanox obtains Sunol’s tissue-factor antagonist cH36- an anti factor monoclonal antibody in development for lung injury, and acute respiratory distress. Tanox will give Sunol’s 800,000 shares of stock and $6 million cash. 2005-03-28T00:00:00 0 15 Biopharmaceuticals Aphton Corporation (APHT) a development stage biopharmaceutical company focused on cancer and other diseases. Igeneon a development stage biopharmaceutical company focused on cancer. Expands Aphton’s product pipeline and oncology R&D initiatives. 2004-12-15T00:00:00 0 16 Biopharmaceuticals Bayer AG (BAYG:DE) a global pharmaceutical and chemical company. Roche a major pharmaceutical diagnostic company. Roche closed the previously announced divestiture of its OTC lines, adding greater critical mass to Bayer's consumer offerings. Roche will concentrate on Rx and diagnostic products. Transaction value about $5.5 billion. 2004-12-31T00:00:00 0 17 Biopharmaceuticals BD Diagnostics BD's diagnostic unit serving healthcare institutions, life science researchers, clinical laboratories, industry, and the public. FFE Weber GmbH (Germany) a developer of technologies to separate and fractionalize complex proteins. Adds to BD's proteomics and protein separation technologies. 2005-05-03T00:00:00 0 18 Biopharmaceuticals Biacore International AB (SSE:BCOR) a supplier of systems for protein interaction analysis. FLEXChip Systems a provider of an open array-based platform for kinetic screening. FLEXChip strengthens Biacore's global position in the field of protein interaction analysis. Transaction value about $4 million. 2005-03-10T00:00:00 0 19 Biopharmaceuticals C.B. Fleet Company, Inc. a manufacturer of personal health and beauty care products. CCS a supplier of pharmaceutical and personal care products in the Swedish market. CCS expands CCS' presence in Nordic region, as well as broadens its product portfolio. 2005-01-13T00:00:00 0 44 Biopharmaceuticals RoundTable Healthcare Partners a private equity firm focused on the healthcare industry CorePharma, LLC a manufacturer of solid dose generic pharmaceuticals. Provides RoundTable with a new platform investment in generic pharmaceuticals and accelerates CorePharma's growth. RoundTable acquired a majority interest with the CorePharma management team retaining a substantial ownership stake. 2005-08-04T00:00:00 0 10 Biopharmaceuticals Protein DesignLabs Inc. a developer of antibodies to treat autoimmune diseases. ESP Pharma, Inc. a company founded to acquire approved and late stage pharmaceuticals. ESP will add commercialization products and more pharmaceuticals to Protein Design Labs portfolio. Transaction value about $500 million. 2005-01-25T00:00:00 0 222 Medical Devices SOLA International Inc. (SOL) a manufacturer of spectacle lenses. Vision Systems Inc. a wholesale laboratory specializing in ultra-high index lenses. Complements and expands SOLA’s existing prescription laboratory network. Transaction value about $8 million. In December, Sola is sold to Carl Zeiss AG. See earlier entry. 2004-11-30T00:00:00 0 67 Biopharmaceuticals Invitrogen Corporation, (Nasdaq: IVGN) a provider of technologies for disease, drug discovery and commercial bioproduction. Caltag Laboratories a manufacturer of immunological reagents. Caltag's expertise in producing antibodies and reagents for flow cytometry adds a key capability to Invitrogen's proteomic portfolio. $20 million cash deal. Caltag's expected revenue is $10 million in next 12 months. 2005-05-17T00:00:00 0 68 Biopharmaceuticals IVAX Corporation (IVX) a multinational manufacturer of generic pharmaceuticals and veterinary products. Polfa Kutno a Polish producer of prescription and over the counter drugs. Increases IVAX’s existing manufacturing capabilities in Central and Eastern Europe and expands its sales force within the Polish market. 2004-12-08T00:00:00 0 69 Biopharmaceuticals Johnson & Johnson (JNJ) a global manufacturer of pharmaceuticals, medical devices and consumer healthcare products. TransForm Pharmaceuticals, Inc. a manufacturer of crystalline forms of drug molecules TransForm will be added to J&J’s line of pharmaceutical research and development. Transaction value about $230 million. 2005-03-09T00:00:00 0 71 Biopharmaceuticals Novartis AG (NVS) a developer and manufacturer of pharmaceuticals and nutritional products. Eon Labs, Inc. (Nasdaq:ELAB) a leading U.S. based supplier of generic pharmaceuticals, and Hexal AG ,, #2 generic pharma company in Germany. Both deals significantly fortify Novartis as the leading generic drug maker in the world. The Eon deal is valued at over $8.0 billion and the Hexal at about $5.6 billion. 2005-02-21T00:00:00 0 72 Biopharmaceuticals Perrigo Company (PRGO) a manufacturer of over-the-counter pharmaceutical and nutritional products. Agis Industries Ltd. a manufacturer of specialized generic pharmaceuticals and active pharmaceutical ingredients. Provides Perrigo with synergetic product lines and additional global manufacturing capabilities. Transaction value about $818 million. 2004-11-15T00:00:00 0 73 Biopharmaceuticals Pfizer Inc. (PFE) a global drug developer and manufacturer. Meridica a designer and developer of drug delivery technologies for the pharmaceuticals industry. Broadens Pfizer’s inhalation drug delivery technologies. Transaction value about $125 million. 2004-11-12T00:00:00 0 74 Biopharmaceuticals PPD, Inc. (PPI) provider of discovery and development services and products for pharmaceutical and biotechnology companies. SurroMed, Inc. a biomarker-enabled drug discovery and development. Adds biomarker discovery and patient sample analysis compatibilities. 2005-01-17T00:00:00 0 42 Biopharmaceuticals Patheon, Inc. (TSX:PTI) a contract manufacturer of pharmaceutical products. MOVA Pharmaceutical Corporation a contract manufacturer of pharmaceutical products. A complementary acquisition that expands Patheon’s customer base and increases its manufacturing capabilities. Transaction value about $350 million. 2004-12-23T00:00:00 0 76 Data Management/ Healthcare IT Affiliated Computer Services, Inc. a provider of business process and IT outsourcing services. Superior Consultant Holdings Corporation (SUPC) a provider of IT services to the healthcare industry. A complementary acquisition which is expected to bolster Affiliated’s existing health care IT services group. 2004-12-17T00:00:00 0 64 Biopharmaceuticals Invitrogen Corporation, (Nasdaq: IVGN) a provider of technologies for disease, drug discovery and commercial bioproduction. Bio Asia a China-based provider of biotechnology R&D supplies and services. Supplements Invitrogen’s existing products and services in the China market. Transaction value about $8 million. 2004-12-08T00:00:00 0 223 Medical Devices Sonic Innovations Inc. (SNCI) a manufacturer of digital hearing aids. Tympany Inc. a manufacturer of audiological diagnostic equipment. Complements Sonic’s existing hearing health care products. 2004-12-07T00:00:00 0 224 Medical Devices St. Jude Medical Inc. (STJ) a manufacturer of cardiovascular medical devices. Irvine Biomedical Inc. a developer of electrophysiology (EP) catheter products for the diagnoses and treatment of cardiac rhythm disorders. The acquisition broadens St. Jude’s EP catheter product line. Transaction value about $47 million. 2004-10-07T00:00:00 0 225 Medical Devices St. Jude Medical Inc. (STJ) a manufacturer of cardiovascular medical devices. Endocardial Solutions, Inc. (ESI) a developer of advanced electrophysiology (EP) mapping and navigation systems. ST. Jude adds proprietary EP systems to its atrial fibrillation solutions. Transaction value about $272 million. See "Deals in the Spotlight" column. 2005-01-13T00:00:00 0 226 Medical Devices St. Jude Medical Inc. (STJ) a manufacturer of cardiovascular medical devices. Velocimed, LLC a manufacturer of specialty interventional cardiology devices. St. Jude will acquire interventional technolcatheterization technologies supplementing its Angio-Seal vascular closure product line. Transaction value about $74 million, plus milestone payments. See "Deals in the Spotlight" column. 2005-02-15T00:00:00 0 227 Medical Devices Sunrise Medical Inc. a manufacturer of wheel chair and other patient mobility and rehab products. Adaptive Equipment Systems (a product of wheel chair seating and positioning systems), RehabiliTech, Inc. (a manufacturer of custom wheelchair seating) and Whitmyer Biomechanix, Inc. (a manufacturer of custom head positioning systems). Supplements Sunrise's wheel chair and patient positioning lines. 2004-10-22T00:00:00 0 228 Medical Devices Sybron Dental Specialties, Inc. a manufacturer of dental consumables and infection control products. Oraltronics Dental Implant Technology, GmbH a manufacturer of dental implants based in Germany. The cash deal, valued at $43.7 million, enables Sybron to expand its foothold in the dental implant market. 2005-06-09T00:00:00 0 229 Medical Devices Synovis Life Technologies Inc. (SYNO) a manufacturer of surgical devices and provider of contract manufacturing services. Neuroregen LLC a developer of neural regeneration related medical devices. The acquisition of Neurotube® complements and expands Synovis’s microsurgical product portfolio. 2004-12-07T00:00:00 0 230 Medical Devices Theragenics Corporation a manufacturer of cancer treatment products. CP Medical a manufacturer of sutures, cardiac pacing cables and related products for surgical and veterinary markets. Creates new growth opportunities for Theragenics and diversifies its product line, while providing a basis for using joint engineering and sales resources. Strengthens the Theragenics' brachytherapy product line. 2005-05-10T00:00:00 0 75 Biopharmaceuticals Takeda Pharmaceutical Company Ltd a Japanese developer of pharmaceutical products. Syrrx Inc a developer of high-throughput protein crystallography systems to speed drug discovery. Syrrx’s technologies and R&D pipeline omplement s Takeda’s established research presence. 2005-02-07T00:00:00 0 56 Biopharmaceuticals West Pharmaceutical Services, Inc. a manufacturer of components and systems for injectable drug delivery, The Tech Group a manufacturer of plastic components and assemblies for the pharmaceutical, medical device, consumer products, and personal care markets. West will pay $140 million for the assets including nine production facilities throughout the country and in Puerto Rico, Mexico, and Ireland. 2005-04-29T00:00:00 0 45 Biopharmaceuticals Safeguard Scientifics, Inc. a provider of business development services for information technology and life sciences companies. Laureate Pharma L.P. a provider of drug and diagnostics development products. Considered a well-positioned growth vehicle for Safeguard. Transaction amount about $30 million. 2004-10-21T00:00:00 0 46 Biopharmaceuticals Schering-Plough Corporation, (SGP) a developer of health care products for advanced drug therapies. NeoGenesis Pharmaceuticals, Inc. a developer of molecular drugs. Strengthens Schering’s capabilities in innovative drug discovery. 2005-01-20T00:00:00 0 47 Biopharmaceuticals SFBC International, Inc. a specialized drug development services company. PharmaNet, Inc. a drug development company. The combined company will provide SFBC with global phase II and III development and technology platforms. 2004-11-03T00:00:00 0 48 Biopharmaceuticals Shire Pharmaceuticals Group plc a British biotech company. Transkaryotic Therapies, Inc. a US-based biopharmaceutical developer of therapeutics primarily for the treatment of rare genetic diseases caused by protein deficiencies. Transkaryotic will help Shire gain access to an area of specialty pharmaceuticals with few competitors. Builds on Shire's European and US specialty sales and marketing capabilities; leverages Shire's experience in renal and hematology. Transaction value about $1.6 billion. 2005-04-22T00:00:00 0 50 Biopharmaceuticals Solvay Pharmaceuticals a research company targeting the therapeutic areas of cardiology, gastroenterology, mental health and gynecology/andrology. ITALMEX a Mexican pharmaceutical company. Strengthens Solvay’s existing gastroenterology and gynecology/urology product lines and adds a sales force of 400 people covering the Mexican market. 2004-12-10T00:00:00 0 51 Biopharmaceuticals Solvay Pharmaceuticals a research company targeting the therapeutic areas of cardiology, gastroenterology, mental health and gynecology/andrology. Fournier Pharma (France) a developer of drugs for lipid disorders and cardiovascular diseases. The acquisition boosts Solvay’s cardiovascular pharmaceuticals and accelerates their overall pharmaceutical business, by adding a strong product line to control cholesterol and triglycerides. Acquisition value of approximately $1.56 billion in cash. 2005-07-14T00:00:00 0 52 Biopharmaceuticals Sonus Pharmaceuticals, Inc. a developer focused on novel drugs for the treatment of cancer. Synt:em a French-based, privately held drug discovery and development company. Will expand and diversify Sonus’ drug development pipeline with a number of potential product candidates. 2004-11-03T00:00:00 0 53 Biopharmaceuticals Stressgen Bioreagants Corporation a subsidiary of Ampersand Ventures. Stressgen Biotechnologies a biopharmaceutical company focused on the development, and commercialization of vaccines for the treatment of infectious diseases and cancer. Ampersand sees Stressgen’s bioreagents business as a leader in the heat shock protein field, with good growth prospects, through the introduction of complementary new products and external, strategic initiatives. 2005-05-02T00:00:00 0 66 Biopharmaceuticals Invitrogen Corporation, (Nasdaq: IVGN) a provider of technologies for disease, drug discovery and commercial bioproduction. Dynal Biotech a manufacturer of magnetic bead technologies used in cell separation and purification, and in proteomics. Was owned by Nordic Capital. Invitrogen will be able to apply Dynal's technology to a number of its existing product lines, such as molecular diagnostic and stem cell research. Transaction value about $391 million. 2005-04-01T00:00:00 0 55 Biopharmaceuticals TEVA Pharmaceutical Industries Ltd (Israel) a manufacturer of generic and active pharmaceutical ingredients. IVAX Corporation a provider of branded and generic pharmaceuticals and veterinary products. Creates largest generic drug manufacturer and adds branded products (for cancer, asthma and multiple sclerosis), as well as generics an deeper drug development pipeline, to Teva's portfolio. It is expected that Ivax's sales will reach $2.7 billion in 2006. The combined company will offer a wide range of pharmaceuticals and it is expected to generate sales exceeding $7 billion a year. The transaction value is $7.4 billion. More than $150 million in cost savings anticipated. 2005-07-25T00:00:00 0 65 Biopharmaceuticals Invitrogen Corporation, (Nasdaq: IVGN) a provider of technologies for disease, drug discovery and commercial bioproduction. Zymed Laboratories Inc. a manufacturer of antibodies. Zymed complements Invitrogen's technology adding more than 2,000 antibodies and related products. Transaction value about $ 60 million. 2005-01-10T00:00:00 0 57 Biopharmaceuticals YM BioSciences Inc. a cancer product development company. DELEX Therapeutics Inc. a private clinical stage biotechnology company developing inhalation products to treat cancer pain. Enhances YM's portfolio of late-stage cancer-focused products. Obtains AeroLEF, an inhalation delivery system that delivers both free and liposomal encapsulated fentanyl, an opioid drug widely prescribed to treat cancer pain. 2005-05-03T00:00:00 0 58 Biopharmaceuticals Antisoma Plc. a British based cancer drug specialist. Aptamera Inc. a developer of cancer pharmaceuticals. Expands Antisoma’s cancer drug portfolio. Transaction value about $22 million. 2005-01-10T00:00:00 0 59 Biopharmaceuticals Bayer AG (BAYG:DE) a global pharmaceutical and chemical company. GlaxoSmithKline PLC a major pharmaceutical company. Bayer acquired the sole marketing rights outside the United States of Levitra, a drug used for erectile dysfunction. Transaction value about $260 million. 2005-01-10T00:00:00 0 60 Biopharmaceuticals Eyetech Pharmaceuticals, Inc. (EYET) a developer of novel therapeutics to treat diseases of the eye. Transgenomic, Inc. (TBIO) a developer of innovative products for use in research, diagnostics and therapeutics. Provides Eyetech with manufacturing capabilities for its upcoming clinical trials. Transaction value about $3 million. 2004-11-15T00:00:00 0 61 Biopharmaceuticals Genetronics Biomedical Corp. (GEB) a late stage developer of oncology therapies using electroporation to deliver drugs and nucleic acids. Inovio AS. a patented gene delivery technology company Adds to Genetronics’ DNA therapies. Transaction value about $13 million. 2005-01-27T00:00:00 0 62 Biopharmaceuticals Genzyme Corporation (GENZ) a global biotechnology company. Verigan AG (Germany) a producer of proprietary cell therapy products for cartilage repairs. Advances Genzymes global orthopedic franchise, with a strong presence in Europe and Australia. Transaction value about $10 million with $40 million milestone payments. 2005-02-08T00:00:00 0 63 Biopharmaceuticals Invitrogen Corporation, (Nasdaq: IVGN) a provider of technologies for disease, drug discovery and commercial bioproduction. DNA Research Innovation, Ltd. a developer of DNA and nucleic acid purification products. Augments Invitrogen’s suite of drug development technologies. Transaction value about $65 million. 2004-10-28T00:00:00 0 231 Medical Devices Thermo Electron Corporation (TMO) a provider of analytical instruments, scientific equipment, services and software solutions. SPX Corporation global provider of technical products and systems, industrial products and services. Thermo acquiring the Kendro Laboratory indirect division, providing Thermo with a more complete line of laboratory equipment. Kendro’s sales were about $375 million and its EBITDA about $65 million (12 x EBITDA). Transaction value about $ 833.5 million 2005-05-11T00:00:00 0 54 Biopharmaceuticals Symyx Technologies, Inc. a developer of instrumentation and software for R&D efforts. IntelliChem, Inc. a provider of intelligent electronic lab notebooks for the pharmaceutical, biotechnology and chemical industries. Augments Symyx’s existing R&D software applications. Transaction value about $28.9 million. 2004-11-15T00:00:00 0 570 Medical Devices MediCor Ltd. a provider of products for medical specialties in aesthetic, plastic and reconstructive surgery and dermatology markets. Biosil Limited and Nagor Limited Biosil: a manufacturer of breast implants; Nagor: a supplier of breast implants. Strengthens MediCor's position as the third leading manufacturer and distributor of breast implants worldwide. 2005-09-13T00:00:00 0 2 253 Medical Devices Medical Makeover Corporation of America a provider of medical grade “makeover” treatments using non-invasive surgical procedures. Aventura Laser and Skin Care a laser reduction aesthetic improvement and skin care business. Medical Makeover will increase its client base, add to its service offerings and be presented with cross-selling opportunities. 2005-04-14T00:00:00 0 2 291 Medical Services Conventry Health Care, Inc. (CVH) a managed health care company that operates health plans, insurance companies, and provider networks. Omnicare Health Plan a managed care provider. Adds $150 million in annual revenues and 63,000 Medicaid members. 2004-10-04T00:00:00 0 293 Medical Services Eclipsys Corporation (ECLP) a healthcare information technology company. ESys Medical Systems Inc. a radiology information systems company. Supplements Eclipsys’s software application site. Announced completion of the acquisition. 2004-12-17T00:00:00 0 294 Medical Services HealthTronics Surgicial Services, Inc. (HTRN) a provider of urology services and manufacturer of urology imaging and therapeutic products. Prime Medical Services, Inc. (PMSI) a provider of healthcare services to the urology community and manufacturer of specialty vehicles. Provides HealthTronics with complementary services to offer its existing urology network. 2004-11-10T00:00:00 0 556 Medical Devices Complete Care Medical, Inc. (CCMI.PK) nc. (CCMI.PK) a provider of disease-management products, medical supplies and prescription drugs to health care organizations. International Medical Devices, Inc. a supplier of diabetes monitoring products and other equipment that treat chronic health-related conditions. Secures supply of diabetes devices for CCM and adds depth to its direct to consumer marketing capabilities. 2005-08-10T00:00:00 0 557 Medical Devices Montagu Private Equity a European private equity firm. BSN Medical an orthopedic products manufacturer created as a 50/50 joint venture between Beiersdorf AG and Smith & Nephew. Montagu believes a singular driven owner, with accompanying private equtiy inducements, will be more effective in growing BSN than joint ownership. BSN makes casting, bandaging, wound care and phebology products. Deal value is $625 million. BSN's revenues exceed $600 million. 2005-12-16T00:00:00 0 559 Medical Services American Laser Centers an operator of laser hair removal clinics. Advanced Laser Clinics, Inc. a franchiser of hair-removal businesses. Creates a national provider with over 100 clinics in 31 states and solidifies the company's position as a significant hair removal and skin rejuvenation company. 2005-09-13T00:00:00 0 289 Medical Services Air Products (APD) a supplier of industrial, gas and chemical equipment. Ultra Care, Inc. an Illinois based provider of homecare respiratory and infusion products. A complementary acquisition which will be integrated into Air Products’ nearby DependiCare operations. 2004-12-09T00:00:00 0 591 Biopharmaceuticals Aptuit, Inc. a provider of drug development services and technologies. Almedica International a provider of clinical drug supply services. Expands Aptuit's clinical trial drug supply capabilities. 2005-08-29T00:00:00 0 286 Medical Services Ventiv Health Inc. (VTIV) a provider of outsourced clinical, sales, marketing, and compliance solutions for the pharmaceutical, biotechnology and life sciences industries. HHI Clinical & Statistical Research Services LLC a provider of statistical analysis and data management services to the pharmaceutical industry. Augments and expands Ventiv’s existing suite of pharmaceutical clinical trial services. 2004-11-22T00:00:00 0 571 Biopharmaceuticals Angiotech Pharmaceuticals, Inc. (ANPI) a Canadian-based specialty pharmaceutical company focusing on combining pharmaceutical compounds with medical devices and biomaterials. Afmedica, Inc. a developer of perivascular technology focused on the extra-vascular delivery of of rapamysicn and its analogs. Extends Angiotech's research and product development platform and strengthens its position with respect to its Vascular Wrap(TM) product development program. 2005-12-01T00:00:00 0 572 Medical Devices Alphatec Spine, Inc. a provider of spinal implants. Cortek, Inc. a manufacturer of allografts for spinal interbody fusion. Provides Alphtatec, owned by Healthpoint Capital, with a wider range of spinal fusion products. Allographs are recognized for accelerating lumbar and cervical repair. 2005-09-13T00:00:00 0 573 Dental Church & Dwight Company, Inc. (CHD) a provder of personal care, household and specialty products, under the ARM & HAMMER brand name and other well-known trademarks. SpinBrush(TM) power toothbrush business of the Proctor & Gamble Company (PG) a major provider a range of consumer products. Strengthens C&D's oral care business and allows P&G to divest the business as part of its antitrust negotiations concernng its pending of purchase of Gilette Co. Transaction value of $75 million cash and milestones payments up to $30 million. Sales of $110 million (80% in the U.S. and Canada). 2005-09-14T00:00:00 0 574 Medical Devices Recom Managed Systems, Inc. (RSY) a developer of medical devices that monitor and measure physiological signals to detect diseases. OTC cardiac event recorder line of TZ Medical, Inc. a provider of cardiovascular products such as intracardiac catheters, cardiac monitors, hemostatic products and defibrillation electrodes . The agreements involve the acquisition of significant existing products and devices that will immediately enhance Recom's market share while expanding its product line. In an additional joint venture agreement, TZ will contribute its line of intracardiac catheters and Recom its patented and patent-pending signal-amplification and noise-reduction technologies. 2005-09-14T00:00:00 0 575 Biopharmaceuticals Pfizer, Inc. (PFE) a global drug developer and manufacturer. Vicuron Pharmceuticals, Inc. (MICU) a biopharmaceutical company focused on the development of novel anti-infectives for both hospital-based and community-acquired infections. Gives Pfizer two new product candidates currently under review at the FDA: anidulafungin for fungal infections and dalbavancin for Gram-positive infections, bolstering its portfolio of anti-infective drugs. Transaction value: $1.9 billion 2005-09-14T00:00:00 0 578 Medical Devices Tyco International Ltd. a diversified manfacturer with substantial medical product lines. Floreane Medical Implants SA (France) a manufacturer of Sofradim surgical mesh implants to provide tissue reinforcement for procedures such as hernia repair, pelvic floor reconstruction, incontinence, urinary, adhesion prevention and obesity surgery. Expands Tyco's surgical product portfolio, with a complementary range of products, and allows Tyco to capitalize on its global sales force and infrastructure. Deal value of $145 million for 41% of the shares and a 55% voting interest. Floreane's sales in 2004 were $31 million. 2005-09-21T00:00:00 0 580 Medical Devices Medtronic, Inc. (MDT) a major manufacturer of cardiovascular and other devices. Image-Guided Neurologics a maker of navigation and guidance products used during brain surgery. Strengthens Medtronic's position in deep brain stimulation, with products that simplify procedures for implanting its Activa Therapy neuro-stimulation devices. 2005-08-30T00:00:00 0 583 Medical Devices Zimmer Holdings, Inc. a leading orthopedic products manufacturer. Revivicor, Inc. via genetic modification, a provider of tissues, cells and whole organs for human therapeutic applications. Zimmer obtained the worldwide exclusive for genetically engineered xenogeneic technology for tissue regeneration. Positions Zimmer as a leader in the development of tissues used to replace or repair damaged human cartilage, ligaments, tendons and bone. 2005-09-20T00:00:00 0 590 Medical Devices Cordis Corporation a Johnson & Johnson Company providing devices and products for interventional vascular medicine and electrophysiology. LuMend, Inc. a provider of devices used to treat vascular disease in the legs and other parts of the body other than the heart. Provides Cordis with devices to treat chronic total occlusions, a peripheral vascular problem. Acquired product lines include special catheters to facilitate guidewire placement in minimally invasive procedures such as angioplasties and stenting. Complements Cordis Endovascular products. 2005-09-28T00:00:00 0 265 Medical Services Apria Healthcare Group, Inc. a provider of home respiratory, infusion therapy and medical equipment services. VitalAire Homecare (US HME operations of Air Liquide, Paris, France) the US home care division of Air Liquide, a supplier of oxygen, nitrogen, hydrogen and many other gases and services to various industries. Air Liquide is leaving the U.S. market to focus on its European activities where it has established solid positions. Terms of the deal have not been disclosed but VitalAire has been valued at $20 million. Apria adds southern locations (northern FL, GA, SC). 2005-07-04T00:00:00 0 257 Medical Devices Pegasus Pharmaceuticals a specialized pharmaceutical manufacturer. Heartview a developer of portable heart-screening devices. Pegasus will acquire 51% of Heartview, including the ECG Cardiovascular 6C System. Intended for doctor’s office, the product is still under clinical trial. 2005-04-14T00:00:00 0 255 Medical Devices Nordic Capital a Swedish private equity firm. Atos Medical AB, a subsidiary of Fisher Scientific International Inc. (FSH) a manufacturers ear, nose, and throat medical devices. Atos had approximately $38 million in revenues for 2004. Transaction value about $110 million. Nordic expects Atos to grow more as an autonomous unit, having been acquired by Fisher as part of its 2003 Perbio Science acquisition. 2005-03-08T00:00:00 0 256 Medical Devices OSI Systems, Inc. (OSIS) a manufacturer of security, inspection and monitoring systems, and a provider of engineering. Blease Medical Holdings Limited a U.K. manufacturer of anesthesia systems, vaporizers and ventilators. Expand’s OSI’s preoperative presence in Europe and Asia. Transaction value about $8.8 million with the potential for additional $11.8 million based on performance targets. 2005-02-08T00:00:00 0 258 Medical Devices Smiths Medical, a subsidiary of Smiths Group plc (LSE:SMIN.L) a manufacturer of medical devices for critical care and surgical settings. Medex Inc. a manufacturer of critical and alternative care medical products. A complementary acquisition that broadens Smiths’ critical care product line and expands its sales force in the North American markets. Transaction value about $925 million See "Deals in the Spotlight" column. 2004-12-06T00:00:00 0 260 Medical Devices Stryker Corporation (SYK) a major manufacturer of orthopedic products and related medical devices. eTrauma .com Corp a developer of software for Picture Archive and Communication Systems (PACS). Expands Stryker’s electronic medical records and PACS capabilities in orthopedics. eTrauma.com had annual sales of $18 million for 2004. Transaction value about $50 million. 2005-02-23T00:00:00 0 261 Medical Devices Thermo Electron Corporation (TMO) a provider of analytical instruments, scientific equipment, services and software solutions. Niton a provider of portable x-ray analyzers. Extends Thermo's product line. Niton had revenues of $36 million for 2004. Transaction value about $40.5 million. 2005-03-31T00:00:00 0 262 Medical Services A4 Health Systems a provider of electronic health record solutions. Canopy Systems, Inc. a provider of web-based utilization review and case management services. Synergistic acquisition that will expand A4’s existing health care product and service portfolio. 2004-12-20T00:00:00 0 290 Medical Services Broadlane a provider of group purchasing and other business services. National Oncology Alliance Inc. a provider of services for oncology physician practices. Provides Broadlane with focused oncological drug sourcing capabilities and clinical experience. 2004-11-04T00:00:00 0 264 Medical Services Alliance Medical Corporation an independent processor of single use medical devices. Vanguard Medical Concepts another independent processor of single use medical devices. Consolidates two competitors, lowers costs and increases operating leverage and customer service capabilities. 2005-08-15T00:00:00 0 588 Medical Services WellPoint, Inc. (WLP) the largest U.S. health insurance provider. WellChoice, Inc. the largest health insurer in New York State, better known as Empire Blue Cross Blue Shield. Expands WP into New York State, giving it a major foothold in the Northeast, bringing in 5 million customers. Combined company will serve 33 million members in 14 states. Together the combined companies will serve more than 33 million lives in 14 states. Transaction value - $6.5 billion. 2005-09-27T00:00:00 0 6500 266 Medical Services Aptuit, Inc. a provider of drug development services and technologies. Preclinical Services, Pharmaceutical Services, and Clinical Trial Supplies business units of Quintiles Transnational Corporation a global contract research organization. Grows Aptuit's pharmaceutical services business while the commercial agreement and cash enables Quintiles to grow internally and meet demands for services in clinical trials and commercial partnerships. Transaction value: $125 million. Aptuit anticipates investing $50 million in the business units over the next three years. 2005-07-19T00:00:00 0 267 Medical Services BIOBASE a German specialist in commercial biological databases. Proteome Inc. a producer of the biological information databases. BIOBASE broadens its portfolio and presence in the U.S., Canada, and elsewhere. 2005-01-19T00:00:00 0 271 Medical Services Fresenius Medical Care North America AG (FMS) a global provider of dialysis products and services. Memphis Kidney LLC an operator of outpatient dialysis facilities. The acquisition expands Fresenius’ existing network of dialysis clinics in the U. S. 2004-11-29T00:00:00 0 272 Medical Services HealthTronics Surgicial Services, Inc. (HTRN) a provider of urology services and manufacturer of urology imaging and therapeutic products. Cascade Urological Services, LLC; Cascade Laser Services, LLC a provider of lithotripsy and prostate laser services to the Seattle area. Healthtronics acquired a 33% interest (terms undisclosed). Broadens Healthtronics' scope of urology services. In 2004, Cascade performed over 1,400 procedures, generating approximately $3 million in revenues. 2005-07-14T00:00:00 0 273 Distribution Henry Schein, Inc. (HSIC) a leading distributor of healthcare products and services to office-based practitioners. Halas Dental Ltd. and Shalfoond Bros. Ltd. providers of dental merchandise and equipment in Australia and New Zealand. Schein acquired these businesses from Australian Pharmaceutical Industries Ltd. The company expects the acquisitions to add about $60.5 million in the first twelve months and add slightly to 2005 earnings. 2005-05-16T00:00:00 0 274 Medical Services MCMC LLC a provider of independent medical reviews, examinations and related services. CareSys, Inc. a provider of customized managed care services and technology solutions for workers’ compensation and disability markets; Solutions 4, a provider of bill review services; and Calculare Technologies, a software provider for property insurers. The acquisitions will diversify MCMC’s product portfolio and expand its claims management and managed care services. 2004-11-04T00:00:00 0 275 Data Management/ Healthcare IT Mercury Computer Systems, Inc. a provider of image processing computer systems. Sohard AG a developer of software solutions for medical imaging. The $23.22 million acquisition enables Mercury to broaden its digital imaging OEM solution portfolio. 2005-06-09T00:00:00 0 282 Medical Services PHNS a full service healthcare management firm for healthcare providers. Hunter Medical Systems, Inc. a medical file records management and information company. Improves PHNS' ability to service its customers will enhance its delivery of a full continuum of services to healthcare providers. HMSI serves 314 hospital and clinic clients in 14 states. 2005-04-01T00:00:00 0 263 Medical Services Aetna (AET) a major insurance and managed care company. Magellan Health Services (MGLN) a behavioral health care service provider. Under an existing agreement Aetna has exercised an option to acquire certain behavioral health care assets from Magellan. The assets, three behavioral health care centers and a provider network, previously provided behavioral health services to Aetna. The acquisition will allow Aetna to bring its behavioral health services in-house and fully integrate them with its other health care services. Transaction amount about $50 million. 2004-12-28T00:00:00 0 626 Medical Devices Cooper Surgical, Inc. a manufacturer of women's' health products and a subsidiary of The Cooper Companies. NeoSurg Technologies, Inc. a manufacturer of reusable and disposable trocar access systems used in laparoscopic surgery. This deal, together with Cooper's acquisition of Inlet Medical, adds $10 million of revenue and helps form the basis for Cooper's building a sales force addressing gynecological surgery call points. Cooper plans to merge the acquired companies into a gynecologic surgical business unit and add additional gynecological surgical products. 2005-11-21T00:00:00 0 602 Distribution Warburg Pincus a leading private equity firm. MP TotalCare a leading distributor of diabetes testing supplies, respiratory medications, urological and ostomy products and wound care supplies directly to customers throughout the United States. Warburg Pincus acquired CCS Medical for approximately $360 million and MP TotalCare for approximately $270 million in separate transactions. The combination creates one of the largest and fastest growing direct-to-consumer providers of diabetes and other medical supplies in the United States. CCS Medical's combined sales force now includes more than 180 professionals. 2005-10-03T00:00:00 0 603 Biopharmaceuticals Altana AG a provider of topical dermatological prescription products. U.S. Dermatology business of GlaxoSmithKline (GSK) a major pharmaceutical company. The acquisition solidifies PharmaDerm's branded pharmaceutical specialty in dermatology. 2005-10-01T00:00:00 0 604 Diagnostics Beckman Coulter, Inc. (BEC) a major manufacturer of laboratory automation products. Diagnostic Systems Laboratories Corporation (DSL) a provider of specialty immunoassays for reproductive endocrinology and cardiovascular risk assessment. Enhances Beckman's position in specialty immunoassay testing. DSL's 2004 sales approximated $34 million. 2005-10-31T00:00:00 0 34 607 Medical Devices Accellent, Inc. a provider of contract manufacturing and design services to medical device manufacturers. Campbell Engineering a precision machining and assembling contract manufacturer specializing in orthopedic implants and instruments. Strengthens Accellent's engineering and production capabilities, in prepartion for its impending sale to KKR. 2005-09-12T00:00:00 0 608 Medical Devices Kohlberg Kravis Roberts & Company (KKR) a private equity firm Accellent, Inc. a provider of contract manufacturing and design services to medical device manufacturers. For $1.27 billion KKR purchases Accellent from a private investment group led by KRG Capital Partners and DLJ Merchant Banking Partners. Positions Accellent to expand its operations and capabilities as a contract manufacturer of medical devices. 2005-10-10T00:00:00 0 619 Diagnostics Apax Partners a leading private equity firm. Spectrum Laboratory Network a leading regional provider of clinical and disease screening services. Apax will help grow Spectrum, which supports more than 7,000 physicians in North Carolina, South Carolina, Georgia, Tennessee and Virginia by performing each day more than 30,000 individual diagnostic tests. 2005-11-11T00:00:00 0 620 Data Management/ Healthcare IT PSS World Medical, Inc. a national distributor of medical products to physicians and elder care providers. Clinical Support Services Inc. a medical-billing and recovery services company. The deal leverages PSS' billing services operation and expands its reach into the California market. 2005-11-11T00:00:00 0 585 Medical Devices Micrus Endovascular Corporation (MEND) a manufacturer of implantable and disposable medical devices used in the treatment of cerebral vascular diseases. Neurologic UK Limited Endovascular products in the United Kingdom a distributor of Micrus Endovascular products in the United Kingdom Enhances Micrus' market penetration in the UK. Initial cash payment of $4.7 million and multi-year revenue-based earn out. For fiscal year 2005, Neurologic UK accounted for 14% of Micrus' revenues. 2005-09-28T00:00:00 0 625 Medical Devices Cooper Surgical, Inc. a manufacturer of women's health products and a subsidiary of The Cooper Companies. Inlet Medical Inc. a manufacturer of trocar closure systems and pelvic floor reconstruction procedure kits. This deal, together with Cooper's acquisition of NeoSurg Technologies, adds $10 million of revenue and helps form the basis for Cooper's building a sales force addressing gynecological surgery call points. Cooper plans to merge the acquired companies into a gynecologic surgical business unit and add additional gynecological surgical products. 2005-11-21T00:00:00 0 615 Diagnostics Varian Inc. a maker of scientific instruments and equipment. PL International Ltd. A U.K. maker of systems for high throughput screening and process monitoring, as well as related consummables and instruments for advanced polymer analysis. Expands Varian's product portfolio and enables PL's products to be sold through Varian's global infrastructure. Deal price -- $42 million in cash, plus a possible $23 million in milestone payments. PL's revenues were about $22 million for the FY ended Sept. 30, 2005. 2005-11-08T00:00:00 0 628 Medical Services The Blackstone Group a global investment and advisory firm. TeamHealth, Inc. a leading provider of outsourced physician staffing and administrative services to hospitals and other healthcare provider. In 1999 TeamHealth was purchased by an investor group comprising Madison Dearborn Partners LLC, Cornerstone Equity Investors LLC, Beecken Petty O'Keefe & Company, and members of TeamHealth's management team. Here, Blackstone seeks to continue TeamHealth's growth. 2005-11-25T00:00:00 0 630 Medical Devices Angiotech Pharmaceuticals, Inc. (ANPI) a specialty pharmaceutical company focusing on combining pharmaceutical compounds with medical devices and biomaterials. Lifespan ePTFE the vascular graft business of Edwards Lifescienes. The acquisition, coupled with arrangements for Edwards to globally distribute certain Lifespan products, enhances the Angiotech's potential. Enables Lifespan to directly sell ePTFE vascular grafts and its Vascular Wrap, while insuring foreign distribution with Edwards. Deal value $14 million. 2005-12-01T00:00:00 0 631 Medical Devices Surge Medical Solutions LLC a producer of engineered medical solutions for cardiovascular surgery emergency services applications. Arrested Heart Products Division of Chase Medical a manufacturer of products that treat heart failure and coronary artery disease. Accelerates SMS' efforts to provide novel cardiovascular medical devices. Deal involves the purchase of various cardiovascular tools and accessories with a an extensive distribution network. 2005-11-03T00:00:00 0 633 Medical Services Warburg Pincus and Soros Private Equity two prominent private equity firms. Parthenon Capital's portfolio company, Spheris, Inc. a provider of medical transcription services to leading acute-care hospitals and group medical practices. This is a recap, with existing management and new ownership. Spheris is the second largest medical transcription company in the U.S. It was formed in 2003 through Total eMed's acquisition of EdiX. New growth initiatives are set under the new program. 2005-11-08T00:00:00 0 638 Distribution Cardinal Health a large distributor of pharmaceutical and other products. Source Medical Corp. a Canadian distributor of medical and surgical supplies. This $67.4 million broadens Cardinal's reach in Canada. 2005-11-23T00:00:00 0 639 Biopharmaceuticals AstraZeneca Plc (AZN.L) a major pharmaceutical company. KuDOS Pharmaceuticals a biotech pharmaceutical firms specializing in cancer therapies based on the inhibition of DNA repair. With this $210 million purchase, AZN bolsters its new product pipeline. In 2004, a newly launched AZN lung cancer pill failed to boost survival in a key study. Investors in KuDOS include Advent Venture Partners, BankInvest Biomedical Venture, Euclid SR Partners, Johnson & Johnson Development Corp (JNJ), Life Science Partners, 3i (III.L) and SV Life Sciences. 2005-12-22T00:00:00 0 643 Medical Devices Roper Industries, Inc. (NYSE: ROP) a manufacturer of engineered products for niche markets. MEDTEC, Inc. a developer of enabling technologies for accurate diagnosis and treatment for cancer care. In this $150 million cash deal, Roper acquires patient positioning devices, image-guided therapy software, and related products and accessories. MEDTEC joins Roper’s expanding medical platform within its Imaging segment, which also includes CIVCO, acquired in June 2005. MEDTEC and CIVCO together are expected to generate approximately $85 million of revenues in 2006. The MEDTEC acquisition is expected to generate approximately $17 million of EBITDA. 2005-12-01T00:00:00 0 645 Diagnostics Bruker AXS Inc. a developer of life science research tools based on X-ray technology and a subsidiary of Bruker BioSciences Corporation Rosentec AG and microanalysis business of Princeton Gamma-Tech Instruments, Inc. These two microanalysis businesses complements Brukers's X-ray technology and takes advantage of its global sales and support infrastructure. 2005-11-15T00:00:00 0 623 Biopharmaceuticals Aptuit, Inc. a drug development services company. InfoPro Solutions a developer of informatics solutions for drug development. Adds informatics services to Aptuit’s portfolio and enables customer access to drug development data and information. 2005-11-14T00:00:00 0 563 Biopharmaceuticals GlaxoSmithKline PLC (GSK) a major pharmaceutical company ID Biomedical Corporation (IDBE) a developer of vaccine products in the United States and Canada. Positions GSK as a leading influenza-vaccine manufacturer, increasing capacity for next generation flu vaccines. Transaction value: $1.4 billion. 2005-09-07T00:00:00 0 252 Medical Devices Jabil Circuit, Inc. (JBL) a provider of electronic manufacturing services. Varian Electronics Manufacturing a subsidiary of Varian (VARI) a supplier of scientific instruments and vacuum technologies. Jabil adds Varian's electronics manufacturing business specializing in high-complexity products in the medical, aerospace, communications and scientific instrument markets. Transaction value about $195 million. 2005-03-11T00:00:00 0 592 Medical Devices Integra Life Sciences Holding Corporation (IART) a manufacturer of neuro and plastic surgical products. The intellectual property estate and clinical trial data of Eunoe, Inc a developer of shunt systems for the treatment of Alzheimer's disease patients Extends Integra's technology base relevant to the management of conditions that require regulation of Cerebrospinal Fluid (CSF) flow within the brain 2005-09-30T00:00:00 0 593 Data Management/ Healthcare IT CCS Consolidated, Inc. (d/b/a CareGuide) a care management company specialized in medical and psychosocial needs of individuals requiring disease and complex care management. Patient Infosystems, Inc.(PATY) a provider of case management services for chronic conditions, maternity managemen and smoking cessation. The pending merger combines leading care and disease management companies supporting the public and private sectors as well as self-insured employers. Integrates population management with member focused care management programs. 2005-09-19T00:00:00 0 594 Medical Devices Invitrogen Corporation (Nasdaq: IVGN) a provider of technologies for disease, drug discovery and commercial bioproduction. Qdot semiconductor nanocrystals line of Quantum Dot Corporation a provider of biomolecular labeling and detection technology. Enhances Invitrogen's molecular probes business and IP portfolio. With the acquisition of the BioPixels unit of BioCrystal and the exclusive licensing of Georgia Tech's nanocluster technology, establishes Invitrogen in labeling and detection technologies. 2005-10-06T00:00:00 0 595 Medical Devices Invitrogen Corporation (Nasdaq: IVGN) a provider of technologies for disease, drug discovery and commercial bioproduction. The BioPixels unit of BioCrystal, Ltd. a producer of fluorescent nanocrystal products. Enhances Invitrogen's molecular probes business. With the acquisition of Quantum Dot and the exclusive licensing of Georgia Tech's nanocluster technology, Invitrogen becomes established in advanced labeling and detection technologies. 2005-10-06T00:00:00 0 597 Biopharmaceuticals PharmaDerm Altana Inc. a division of Altana, Inc. a specialty pharmaceutical manufacturer of topical dermatological prescription products. the prescription dermatology business of GlaxoSmithKline Corporation (GSK). a major pharmaceutical company. Broadens PharmaDerm's current portfolio and enhances its sales and marketing effort with an expanded offering. 2005-09-30T00:00:00 0 598 Diagnostics Nautic Partners, LLC a private equity firm. Internation Radiology Group and its subsidiary American Imaging Management, Inc. providers of diagnostic imaging management services. Allows the newly created corporation, AIM Holding Company to invest in new technologies and take the company to the next level, simplifying its management structure. Nautic invested $37 million of equity capital. Other terms of the agreement were not discolosed. 2005-06-28T00:00:00 0 600 Medical Devices Roundtable Healthcare Partners a healthcare industry private equity firm Instrumed international, inc. a manufacturer and provider of surgical instruments primarily to OEM accounts. Roundtable's origins are from V. Mueller (Cardinal Allegiance) and global instrument markets. Here, it buys a majority stake in a U.S. and German business it knows well. 2005-10-17T00:00:00 0 601 Distribution Warburg Pincus a leading private equity firm. CCS Medical a leading direct-to-consumer provider of medical supplies to patients suffering from chronic conditions such as diabetes and chronic obstructive pulmonary disease (COPD). Warburg Pincus acquired CCS Medical for approximately $360 million and MP TotalCare for approximately $270 million in separate transactions. The combination creates one of the largest and fastest growing direct-to-consumer providers of diabetes and other medical supplies in the United States. CCS Medical's combined sales force now includes more than 180 professionals. 2005-10-03T00:00:00 0 562 Biopharmaceuticals GlaxoSmithKline PLC (GSK) a major pharmaceutical company. The Marietta, PA vaccine production facility of Wyeth (WYE) a global pharmaceutical and health care products company. The purchase follows GSK's recent acquisition of Corixa. GSK plans to invest $100 million to develop and produce flu vaccines using a new tissue culture technology expanding US production. 2005-09-01T00:00:00 0 617 Biopharmaceuticals Dr. Reddy's Laboratories (NYSE:RDY) an India-based emerging pharmaceutical company. Roche's Mexican-based active pharmaceutical ingredient (API) plant Strengthens Dr. Reddy's custom pharmaceutical business globally (hoping to grow it from $10 million to $100 million over the next 18 months). 2005-11-11T00:00:00 0 564 Biopharmaceuticals EpiCept Corporation a developer of specialty pharmaceuticals focused on topically-delivered prescription pain management therapeutics. Maxim Pharmaceuticals, Inc. (MAXM) a developer of biopharmaceuticals for cancer and liver diseases. Creates a company with a balanced portfolio of pain management and oncology product candidates, making the company less reliant on any one product candidate. The transaction value is $136 million in stock. 2005-09-06T00:00:00 0 566 Data Management/ Healthcare IT IMS Health, Inc. (RX) a provider of information solutions to the pharmaceutical and healthcare industries. Pharmetrics, Inc. a provider of healthcare market insights utilizing patient-centric integrated claims data. Provides enhanced understanding of how medical and pharmaceutical interventions combine to affect outcomes. 2005-08-09T00:00:00 0 609 Medical Services Global Healthcare Exchange, LLC (GHX) a provider of electronic trading exchange products and services to the healthcare industry. Neoforma, Inc.(NEOF) a provider of supply chain management solutions for the healthcare industry. The combined company will offer supply chain products and services which improve efficiencies for both providers and suppliers. Neoforma has not been profitable. 2006-03-06T00:00:00 0 610 Diagnostics Alliance Imaging, Inc. (AIQ) a provider of diagnostic imaging services. PET Scans of America Corporation a mobile provider of PET and PET/CT services primarily to hospitals. The $44 million cash transaction expands Alliance's geographical reach and its PET and PET/CT capabilities. 2005-10-12T00:00:00 0 611 Medical Devices St. Jude Medical, Inc. (STJ) a manufacturer of cardiovascular medical devices. Advanced Neuromodulation Systems, Inc. (ANSI) a manufacturer of implantable neuromodulation devices for disorders of the central nervous system. Provides St. Jude with a complementary technology platform in a rapidly-growing and under penetrated market gaining an immediate footprint, a broad portfolio and strengthening its international presence. The technology crossover will benefit both neuromodulation and cardiac rhythm management. Transaction value: $1.3 billion. Medtronic leads the sector, with ANSI in second and Cyberonics in third. STJ sought to buy Cyberonics for $525 million in 2004. 2005-11-29T00:00:00 0 612 Medical Devices Natus Medical Incorporated (BABY) a provider of equipment used for testing and treatment of disorders in newborns and children. Bio-logic Systems Corporation (BLSC) a provider of computer-based electro-diagnostic systems for treatment, diagnosis and monitoring of certain hearing, neurological and sleep disorders. Expands Natus' presence in the audiology and diagnostic sleep markets and enlargens its US and international distribution channels. The transaction value $66 million. 2005-10-17T00:00:00 0 613 Medical Devices Duramed Pharmaceuticals, Inc. a subsidiary of Barr Pharmaceuticals (BRL) and a provider of generic and proprietary pharmaceuticals. FEI Womens' Health, LLC a provider of the IUD devices. Expands Duramed's presence and commitment beyond oral contraception and into the non-hormone contraceptive marketplace. FEI owns the New Drug Application (NDA) for the ParaGard® T 380A (Intrauterine Copper Contraceptive) IUD which is the only contraceptive approved for 10 years of continuous use and is more than 99% effective at preventing pregnancy. Transaction value: $281.5 million. FEI's 50-person sales force will be integrated with Duramed's, making a total of more than 100 salespersons. 2005-11-10T00:00:00 0 586 Medical Devices Soteira, Inc. a producer of products used in the treatment of degenerative diseases of the spine. Competitive Technologies, Inc. (CTT) a provider of patent and technology licensing, and commercialization services worldwide. Grants Soteira exclusive license to manufacture and sell CTT nanotechnology bone material for applications related to the human spine. Enhances Soteira's position in the $2.5 billion spinal products market. Annual license fee and milestone and royalty payments. 2005-09-20T00:00:00 0 561 Dental Lifecore Biomedical, Inc. (LCBM) a provider of biomaterials and medical devices for use in various surgical and dental markets. Bardo-Biotech SAS (France) a distributor of dental implants. Positions the Lifecore brand in key European markets, driving continued penetration and complementing r subsidiaries in Germany, Italy and Sweden. 2005-08-31T00:00:00 0 180 Medical Devices Eye Dynamics, Inc. a provider of health and safety products. OrthoNetx, Inc. a manufacturer of systems for osteoplastic surgery and distraction osteogenesis. A synergistic merger in which OrthoNetx's president will become president of the combined company. 2005-03-25T00:00:00 0 254 Medical Devices Merge Technologies Inc. (MRGE) a medical imaging software and services company. AccuImage Diagnostics Corp. (OTCBB: AIDP) a developer of software for advanced analysis of medical imaging data. Supplements Merge’s existing RIS/PACS products and services. Transaction value about $6 million. 2004-11-24T00:00:00 0 171 Medical Devices Delphi Medical Systems a manufacturer of dialysis, infusion, respiratory care, vital signs monitoring and power mobility products. Subsidiary of Delphi Corp. (DPH). Peak Industries Inc. a contract manufacturer of medical devices. Provides Delphi access to new customers in its target markets and additional manufacturing capabilities. Transaction amount about $44 million. 2004-12-07T00:00:00 0 172 Medical Devices Dentsply International Inc. a manufacturer of a broad range of dental products. Glenroe Technologies a manufacturer of orthodontic accessory products. Dentsply obtains products and components used in and with other Dentsply products, adding $7-8 million in orthodontic revenue. 2005-05-17T00:00:00 0 173 Medical Devices DFB Pharmaceuticals, Inc. a manufacturer of wound care, dermatology and surgical products. IsoTis OrthoBiologics (TSX:ISO) a manufactures of bone graph substitutes. DFB acquires the Allox, Epidex and AcuDress wound management products from IsoTis. 2004-12-20T00:00:00 0 174 Medical Devices DiaSys Corporation (DYX) a diagnostic products company. Biocheck, Inc. and New Biotech a manufacturer of immunodiagnostic test kits. Enables DiaSys to advance its growth plan dramatically. 2005-01-05T00:00:00 0 176 Medical Devices Eastman Kodak Company (EK) a manufacturer of imaging products. OREX Computed Radiography Ltd. a provider of compact computed radiography (CR) systems. Gives Kodak access to orthopedics, imaging centers and dentistry markets that favor compact CR products. Complements Kodak’s existing products line. Transaction value about $51 million, 1.8 x revenue. 2005-01-18T00:00:00 0 177 Medical Devices Encore Medical Corporation (ENMC) a manufacturer of orthopedic devices Osteoimplant Technology, Inc. a manufacturer of spinal implant devices and joint design. Adds proprietary spinal fixation systems and other spinal technologies. Transaction value about $16 million, including milestone payments. 2005-02-03T00:00:00 0 169 Medical Devices CTI Molecular Imaging, Inc. (CTMI) a provider of positron emission tomography (PET) equipment, and molecular imaging biomarkers and services. ImTek, Inc. a provider of micro-CT systems for imaging laboratory animals used in medical research. Augments CTI’s service to the research and pharmaceutical markets. 2004-11-08T00:00:00 0 179 Medical Devices Essilor of America, Inc. a leading manufacturer of optical lenses in the United States and founding partner of VisionWeb, an Internet-based tool for eye care providers. The Spectacle Lens Group J&J Vision Care’s ophthalmic lens business. Enhances Essilor’s progressive lens business. 2005-06-08T00:00:00 0 168 Medical Devices CAS Medical Systems Corporation a manufacturer of blood pressure measurement and other monitoring products. Statcorp, Inc. a company specializing in the design and manufacture of blood pressure cuffs and blood filters. Extends CAS' product offerings in blood pressure accessories markets. 2005-05-16T00:00:00 0 181 Medical Devices Fresenius Medical Care AG (Germany) a leading provider of dialysis products and services. Haemotec (Quebec) a manufacturer of hemodialysis concentrates. Broadens Fresenius' dialysis products manufacturing capabilities 2005-04-22T00:00:00 0 182 Medical Devices Gyrus Group PLC (United Kingdom) a manufacturer of surgical products. ACMI Corporation a maker of urologic, gynecologic and endoscopic products. In this $500 million deal, Gyrus expands its minimally invasive portfolio and call points. Divestiture by Fox Paine & Company, LLC. ACMI had sales of $185 million and EBITDA earnings of $27 million. See "Deals in the Spotlight" for details. 2005-06-16T00:00:00 0 183 Medical Devices Hansen Medical a developer of technology for the placement of cardiac catheters. Endovia Medical a developer of minimally invasive surgery instruments. Hansen will attain 33 issued and pending patents and patent applications involving robotics and instinctive catheter movement during MIS. 2005-04-15T00:00:00 0 184 Medical Devices Helix Technology Corporation (HELX) a manufacturer of specialized vacuum pumping and measurement systems. Polycold Systems Inc., a subsidiary of Intermagnetics General Corporation (IMGC) a manufacturer of medical devices and energy technology. Intermagnetics divested its Polycold subsidiary to expand its medical device business, MRI magnets, MRI sub-systems and patient monitoring systems. Transaction value about $53 million. 2004-12-16T00:00:00 0 185 Medical Devices Hologic, Inc.(HOLX) a provider of diagnostic imaging systems focused on women's health. The mamography intellectual property of Fisher Imaging Corporation a provider of specialty and general purpose imaging systems. The acquisition completed on 9/29/05 provides Hologic with the SenoScan® digital mammography and MammoTest® stereotactic breast biopsy systems for $32 million. Expands Hologic's market share in women's health and adds technology and customer relationships. 2005-09-29T00:00:00 0 186 Medical Devices Hospira, Inc. a manufacturer of specialty pharmaceutical and medication delivery products. Physiometrix, Inc. a developer of non-invasive medical devices primarily used in neurological monitoring applications. Strengthens Hospira's position in patient safety during surgical and diagnostic procedures, providing sedation monitoring products. Transaction valued at $23 million. 2005-08-01T00:00:00 0 187 Medical Devices Huntleigh Technology plc (U.K.) a manufacturer of products for pressure ulcers, patient positioning and transportation, pneumatic compression and diagnostics. The cardiovascular and obstetric analysis and monitoring businesses of VIASYS Healthcare Inc. a manufacturer of respiratory, neurology, orthopedic and disposable products. Adds the Sonicaid™ and Medilog™ diagnostic products and sales through Huntleigh's existing distribution network. Transaction size ~ $7.1 million. These product lines were part of Viasys' acquisition of Oxford Instruments Medical. 2005-07-01T00:00:00 0 188 Medical Devices Illumina, Inc. (ILMN) a developer of bead array technology. CyVera Corporation a developer of scanning systems for digital bead technology. Will provide Illumina with a comprehensive approach to bead-based assays for biomarkers, R&D and in-vitro and molecular diagnostic opportunities. Transaction value about $17.5 million. 2005-01-22T00:00:00 0 178 Medical Devices Endius, Inc. a manufacturer of medical devices and implants for minimally invasive spine (MIS) surgery. Intellectual property of Dr. Parviz Kambin. a leader in the advancement of MIS surgery. Increases Endius’s MIS technologies and capabilities. 2004-10-26T00:00:00 0 157 Medical Devices ArthroCare Corp. (Nasdaq:ARTC) a manufacturer of coblation (ablation) technology products to dissolve targeted soft tissue. Applied Therapeutics, Inc. a producer of Gel Knit nasal dressings and dissolvable Sinu Knit stents used after endoscopic sinus surgery to control minor bleeding. Arthrocare distributed Applied's wound care products in select areas, now adding the $5 million lines to its own. $10 million transaction price. 2005-08-17T00:00:00 0 148 Medical Devices W.L. Gore & Associates, Inc. a manufacturer of products for electronics, industrial, fabrics and medical markets. Tetrad Corporation a manufacturer of medical ultrasound probes, imaging systems and surgical products. Both companies use each other's products, creating a broader ultrasound and imaging product offering. 2005-04-07T00:00:00 0 149 Medical Devices Abbott Laboratories (ABT) a global developer and manufacturer of pharmaceuticals and medical products. Spine Next, S.A. (France) a producer of spinal fixation products. Broadens Abbott's spinal product line, adds non-fusion spinal technology and capitalizes on its global distribution. Transaction value about $60 million. See the December 2004 Report: "Deal in the Spotlight". 2004-10-25T00:00:00 0 150 Medical Devices Abiomed, Inc. a manufacturer of products for circulatory care. Impella CardioSystems AG a maker of minimally invasive cardiovascular support systems (micro blood pumps, etc.). Takes Abiomed into the cath lab and diversifies it away from the artificial heart. $4.04 million in stock, about $2 million in cash, and $29 million in contingent milestone payments. 2005-05-10T00:00:00 0 151 Medical Devices Accuray Inc. a manufacturer image guided full body radio surgery systems. American Science and Engineering, Inc. (ASEI) a mfger of X-ray detection technology. A sale of certain assets giving Accuray exclusive rights to linear accelerators for medical application. Provides a component of Accuray’s Cyberknife (stereotactic radiosurgery system). 2005-01-14T00:00:00 0 152 Medical Devices American Capital Strategies an investment firm. Stamping Specialties a manufacturer of medical implant materials. Stamping specializes in wrenches for installation of pacemakers and other implantable devices. Transaction value about $50 million. 2005-04-14T00:00:00 0 153 Medical Devices American Medical Systems, Inc. (AMMD) a manufacturer of products to treat male and female pelvic conditions. Ovion, Inc. a developer permanent birth control alternatives without surgery. Broadens AMS' gynecological product base with office-based technology. FDA approval is anticipated by late 2008. Transaction value of $10 million cash and $20 million in milestone payments with contingent payments equal to net sales for the 12-month period after commercialization. 2005-07-07T00:00:00 0 154 Medical Devices Ampac Packaging, LLC (Ampac) a producer of film for bags, medical devices, pharmaceuticals and food packaging. Flexicon, Inc. a manufacturer of flexible packaging materials for the pharmaceutical, medical, healthcare, chemical, food and industrial markets. Grows Ampac’s consumer division. 2005-01-14T00:00:00 0 170 Medical Devices Cytyc Corporation (CYTC) a manufacturer of woman’s health products. Proxima Therapeutics, Inc. a developer of cancer treatments. Cytyc gains the right to MammoSiteâ, a single use breast cancer treatment. The product had 2004 revenues of about $12.6 million. Transaction value about $160 million, plus additional cash payouts based on sales growth. 2005-02-09T00:00:00 0 156 Medical Devices Argon Medical Devices, Inc. a manufacturer of single-use vascular access and pressure monitoring devices for cardiology, radiology and critical care. Clinical Innovations, Inc. a manufacturer of single-use medical devices used primarily in the women's health, urology, and gastroenterology markets. Roundable Healthcare Partners founded Argon to make this synergistic acquisition and form ACI Medical Devices, Inc. Complementary products, though sold into diverse markets. 2005-05-03T00:00:00 0 192 Medical Devices Invacare Corporation (NYSE:IVC) a leading manufacturer and distributor of home and long-term care medical products. Medical Support Systems Holdings (United Kingdom) a designer and manufacturer of foam pressure-reducing products. Adds high quality mattresses, overlays and cushions for both armchairs and wheelchairs to Invacare's product lines, with European markets exposure. 2005-04-20T00:00:00 0 158 Medical Devices Aspen Surgical Products, Inc. a manufacturer of disposable medical products for the O.R. environment Sterion Inc. (STEN) a provider of emergency oxygen equipment and related products and services. The sale includes the Sterion’s disposable operating room support products, private label manufacturing, and the Surgidyne brand of surgical wound drainage products. The deal broadens Aspen’s O.R. product offering. Transaction value about $6.5 million. 2004-11-08T00:00:00 0 159 Medical Devices Best Medical International, Inc. a developer of radiation products for the oncology, urology, neurology and gynecology markets. Vascular Brachytherapy (VBT) business of Novoste Corporation (NASDAQ:NOVT) a leader in products for vascular brachytherapy - radiation therapy delivered inside a blood vessel to prevent its reclosure (restenosis) following catheter-based interventional procedures. As per this asset purchase agreement, Best re-enters the VBT market with the last remaining independent VBT on the market. (Cordis/J&J and Guidant also offer VBT systems.) Best will market the Novoste VBT product line to existing Novoste customers and new cardiology accounts garnered by Best. 2005-08-25T00:00:00 0 161 Medical Devices Boston Scientific Corporation (BSX) a manufacturer of medical device products for interventional medical specialties. Rubicon Medical Corporation a manufacturer of interventional vascular products. Rubicon's filter, designed to capture and remove dislodged embolic material, synergizes with other Boston Scientific interventional products, including the Taxus drug-eluding stent. The deal, which closed, was previously announced and executed via tender offer and back-end merger. Value -- $71.7 million, plus $83.7 million more if certain milestones are met. 2005-06-15T00:00:00 0 162 Medical Devices Boston Scientific Corporation (BSX) a manufacturer of medical device products for interventional medical specialties. Biophan Technologies a developer of technology to make biomedical devices safe and image compatible in conjunction with Magnetic Resonance Imaging (MRI). Grants Boston Scientific licensing covering patents relating to MRI safety and image compatible technologies, thereby enhancing Boston's implantable capabilities. Transaction value of $5.75 million in investments and licensing payments . 2005-08-03T00:00:00 0 163 Medical Devices Cambrex Corporation a provider of biopharmaceutical therapeutic products. Ortec International, Inc. a producer of skin regeneration products. This is an exclusive marketing and distribution agreement, availing of Cambrex's dedicated sales force. 2004-10-18T00:00:00 0 164 Medical Devices Camp Healthcare Inc., a subsidiary of The Trulife Group (Ireland) a maker of post-mastectomy prosthetic, pressure care and ortho-support products. Seattle Systems, Inc. a leading manufacturer of prosthetics, orthotics, non-invasive orthopedic products and podiatry products. Substantially broadens Trulife/Camp's product lines to include full array of O&P products and advanced orthopedic bracing, while broadening product offerings to its existing customer base and opening up new sales channels. The Walden Group, Inc. represented Seattle Systems in the transaction. Terms not disclosed. 2005-06-30T00:00:00 0 166 Medical Devices Carl Zeiss AG a manufacturer of ophthalmologic diagnostic products and EQT Partners, a private equity firm. SOLA International Inc. (SOL) a manufacturer of spectacle lenses. The combination creates a global ophthalmic lenses company with revenues of approximately EUR 800 million and 9,000 employees. Transaction value about $1.1 billion. 2004-12-05T00:00:00 0 167 Medical Devices Carl Zeiss Meditec Inc. a manufacturer of ophthalmologic diagnostic products. Laser Diagnostic Technologies Inc. a developer and manufacturer of glaucoma diagnostic equipment and management tools. Broadens and expands CZM’s glaucoma diagnostic and management product lines. 2004-12-03T00:00:00 0 155 Medical Devices Animas Corporation (PUMP) a manufacturer of insulin infusion pumps and related products. Cygnus, Inc. (OTCBB:CYGN) a manufacturer of non-invasive glucose monitoring devices. Provides Aminas with a line of minimally invasive glucose sensing products to complement its existing insulin pump products. 2004-12-16T00:00:00 0 242 Medical Devices Boston Scientific Corporation (BSX) a manufacturer of medical device products for interventional medical specialties. TriVascular, Inc. a developer of less invasive medical devices for treating abdominal aortic aneurysims (AAA). Adds novel stent grafts and further BSX's cardiovascular portfolio. 2005-04-18T00:00:00 0 216 Medical Devices PhotoMedex Inc. (PHMD) a manufacturer of medical laser products and related services. ProCyte Corporation (OTCBB: PRCY) a manufacturer of skincare products. Broadens PhotoMedex’s skin care product line and expands its dermatology sales force. Transaction value about $24 million. 2004-12-01T00:00:00 0 217 Medical Devices ResMed Inc (RMD) a manufacturer of sleep and respiratory disorder products. Resprecare Medical B.V. a medical products distributor based in the Netherlands. Resmed’s acquisition of its exclusive distributor in the Netherlands expands its direct sales in Europe. 2004-12-14T00:00:00 0 218 Medical Devices ResMed Inc (RMD) a manufacturer of sleep and respiratory disorder products. Saime S.A. a developer and distributor of ventilation products in France and Germany. Rounds out ResMed's line of homecare ventilation products. Deal value ~ 86 million Euro. 2005-05-09T00:00:00 0 219 Medical Devices SanuWave, Inc. a manufacturer of non-invasive surgical products for orthopedic conditions. The company is controlled by Prides Capital Partners LLC. The orthopedic electrocorporeal shockwave lithotripsy business of HealthTronics (HTRN) a provider of urology services and manufacturer of urology imaging and therapeutic product. Expands SanuWave's orthopedic technology base and positions it for growth in non-urological shockwave treatment. Allows HealthTonics to focus on core urology business lines. Transaction value of $10.4 million. 2005-08-02T00:00:00 0 220 Medical Devices Siemens Medical Solutions Ultrasound Division a leading diagnostic imaging products manufacturer. Sensant Corp. a privately-owned manufacturer of advanced volumetric imaging technology. Allows Siemens to develop advanced volumetric (4D) Capacitive Microfabricated Ultrasound Transducer technology, and commercialize next-generation transducers based on this new technology. "Enables higher frequency imaging, which will allow clinicians to view the smallest details within the body, but the integrated circuit technology should also deliver superior quality control and manufacturing processes" -- from the president and CEO of Siemens Medical Solutions Ultrasound Division. 2005-06-16T00:00:00 0 221 Medical Devices Siemens Medical Solutions USA, Inc. a global supplier of solutions and services in the field of electronics and electrical engineering. CTI Molecular Imaging, Inc. a manufacturer of scanners used to detect cancer and other infectious diseases. Expands molecular imaging competencies of Siemens Medical Solutions. Transaction value about $1 billion. 2005-03-18T00:00:00 0 238 Medical Devices Zimmer Holdings, Inc. a leading orthopedic products manufacturer. Universal Plate Technology a trauma fixation system designed by Swiss Orthopaedic Solutions, a private company. The locking system allows Zimmer to apply the design to its own Plate and Screw product line. 2005-03-29T00:00:00 0 189 Medical Devices Integra Life Sciences Holding Corporation (IART) a manufacturer of neuro and plastic surgical products. Newdeal Technologies a French-based manufacturer of specialty implants and instruments for foot and ankle surgery. Newdeal will provide access to orthopedic markets, synergizes with Integra’s wound care product line and adds to its European direct sales force. Transaction value about $53 million. 2005-01-03T00:00:00 0 240 Medical Devices Biophan Technologies, Inc. (OTCBB:BIPH) a developer of MRI technologies. AMRIS GmbH a manufacturer of MRI-safe medical devices and systems. Enhances Biopan's MRI-related products and adds technical personnel and management within European markets. 2005-01-25T00:00:00 0 579 Dental Sirona Dental Systems (Germany) a provider of high-technology dental equipment. Schick Technologies, Inc. (SCHK.OB) a provider of digital dental imaging systems. Broadens Sirona's reach in the market, enhancing its global presence and product offering. The transaction is valued at $1.9 billion. The combined company for the 12 months ended 6/30/05 had revenue of $500 million worldwide ($180 million in North America) and pro forma EBITDA of $120 million. 2005-09-26T00:00:00 0 243 Medical Devices Boston Scientific Corporation (BSX) a manufacturer of medical device products for interventional medical specialties. CryoVascular Systems, Inc. a developer of treatments for peripheral vascular and cardiovascular disease. Adds innovative technologies to treat peripheral vascular disease (revascularizes the artery and reduces restonsis). 2005-04-20T00:00:00 0 244 Medical Devices Cardiac Science, Inc. (DFIB) a manufacturer of public-access defibrillators. Quinton Cardiology Systems, Inc. (QUIN) a manufacturer of advanced cardiology products. The merged companies combines many cardiovascular products, including holter monitors, stress test systems, cardiac rehab telemetry systems, and cardiology data management systems, in addition to defibrillators Anticipated annual revenues of $160 million based on 2005 figures. 2005-09-01T00:00:00 0 245 Medical Devices CardioTech International, Inc (CTE) a developer of medical devices focused on treatments for late-stage cardiovascular disease. CarTika Medical, Inc. a medical device contract manufacturer. This acquisition expands CardioTech’s catheter and disposables contract manufacturing capabilities. 2004-11-23T00:00:00 0 246 Medical Devices Cochlear Ltd. a manufacturer of hearing implants. Nobel Biocare Holing AG a manufacturer of hearing and dental implants. Noble and an investor group are divesting a hearing implant subsidiary Entific Medical Systems, which will provide Cochlear with technology to treat conductive hearing loss and single-sided deafness. Entific's revenues for 2004 were approximately $40 million. Transaction value about $152 million. 2005-03-04T00:00:00 0 247 Medical Devices Dentsply International Inc. a manufacturer of a broad range of dental products. Raintree Essix, L.L.C. a developer of specialty plastic sheets for retainers and orthodontic treatments. Raintree is expected to add another $7-8 million in revenues to Dentsply's expanding orthodontic offerings. 2005-05-17T00:00:00 0 249 Medical Devices Ethox Corporation a medical contract manufacturer, sterilizer and producer of proprietary disposables. STS duo TEK, Inc. a contract testing facility and sterilizer. Expands Ethox’s laboratory testing capabilities. 2005-02-16T00:00:00 0 250 Medical Devices Implant Science a manufacturer of products for national security, medicine and industry. Accurel Systems International a commercial laboratory. Accruel's semiconductor failure analysis systems fit into Implant’s semiconductor unit. Transaction value about $11.3 million. 2005-03-14T00:00:00 0 251 Medical Devices IntegraLife Sciences Holding Corporation (IART) a manufacturer of neuro and plastic surgical products. NewdealTechnologies a French-based manufacturer of specialty implants and instruments for foot and ankle surgery. Provides access to orthopedic markets, synergizes with Integra’s wound care product line and adds to its European direct sales force. Transaction value about $50 million. 2004-11-14T00:00:00 0 239 Medical Devices Agfa-Gevaert a manufacturer of imaging systems for printing, graphic arts, motion picture, and medical imaging processes. Heartlab a leading designer and supplier of digital image and information networks for cardiology. The $132.5 million deal strengthens Agfa’s position in healthcare information technology, enhancing its cardiology portfolio and presence in US hospitals. Heartlab's revenue and EBITDA were $38.3 million and $5.4 million, respectively. 2005-04-20T00:00:00 0 204 Medical Devices MicroMed Technology, Inc. a developer of miniaturized implantable ventricular assist technologies Salmon Express a publicly-owned shell Enables Micromed, renamed MicroMed Cardiovascular, Inc., go public and better promote its VAD technology. 2005-08-10T00:00:00 0 147 Medical Devices Viasys Healthcare Inc. (VAS) a provider of respiratory, neurology, medical disposable and orthopedic products. Navion Biomedical Corporation a manufacture of catheters placement products. Viasys will own the NAVIGATOR systems which are designed to aid in the corrct placement of peripherally interested catheters. 2005-01-24T00:00:00 0 193 Medical Devices Invacare Corporation (NYSE:IVC) a leading manufacturer and distributor of home and long-term care medical products. Altimate Medical, Inc. a manufacturer of standing frames and mobility aids for the rehabilitation market. Complements Invacare’s offerings to the rehab market. 2005-06-09T00:00:00 0 194 Medical Devices Invacare Corporation (NYSE:IVC) a leading manufacturer and distributor of home and long-term care medical products. Champion Manufacturing, LLC a manufacturer of seating for hemodialysis, chemotherapy and other applications. Expands Invacare's product line and enables its vast distribution system to propel Champion product sales. 2004-10-16T00:00:00 0 196 Medical Devices Johnson & Johnson (JNJ) a global manufacturer medical devices and consumer healthcare products. Closure Medical Corporation a manufacturer of medical adhesives for wound closure and wound care. In this $370mm cash deal, J&J/Ethicon acquires the Dermabond line of topical adhesives and surgical sealants. The line complements Ethicon's wound care business. 2005-03-04T00:00:00 0 197 Medical Devices Laboratory Corporation of America Holdings (NYSE:LH) an independent clinical laboratory company. US Pathology Labs, Inc. a provider of anatomic pathology and oncology testing services. Augments LabCorp’s existing pathology and oncology testing capabilities and provides additional laboratory testing facilities. Transaction value about $155 million. 2004-12-14T00:00:00 0 199 Medical Devices MedSys Corp. (OTCBB: UMSY) a healthcare marketing and distribution company . New England Orthotic and Diabetic Shoe Company a manufacturer of special shoes. Provides MedSys with its own product line to market and distribute. Terms not disclosed. 2004-12-06T00:00:00 0 200 Medical Devices Medtronic, Inc. (MDT) a major manufacturer of cardiovascular and other devices. Angiolink Corporation a manufacturer of wound closure products for vascular procedures. Products complement Medtronic’s coronary and peripheral vascular businesses. 2004-11-04T00:00:00 0 201 Medical Devices Medtronic, Inc. (MDT) a major manufacturer of cardiovascular and other devices. Karlin Technology, Inc. a developer of spine related intellectual property. Medtronic obtains rights to all current applications and future spine products developed by Karlin. The acquisition ends ongoing IP legal disputes. Transaction value about $1.3 billion. 2005-04-22T00:00:00 0 215 Medical Devices Pelikan Technologies Inc. a developer of hand-held diagnostic products. Inventus Bio Tec GmbH & Co. KG a German developer of novel electrochemical sensors. Provides Pelikan with technology and IP to further enhance the development of its own glucose monitoring system. 2004-12-14T00:00:00 0 203 Medical Devices Merit Medical Systems, Inc. (MMSI) a manufacturer of proprietary disposable products sold primarily to radiology and cardiology call points. MedSource Packaging Concepts a custom packager of hospital procedure kits. Adds disposable kits to product line. Transaction amount about $1 million. 2004-11-18T00:00:00 0 214 Medical Devices Otto Bock Healthcare a German-based prosthetic manufacturer. OrthoRehab Inc. an orthopedic rehabilitation products company. Leader in continuous passive motion devices and therapies. Otto Bock acquires several key rehab lines and service facilities, as well as a sales force to channel Otto Bock products. The OrthoRehab network is comprised of 70 offices in 50 countries. Terms not disclosed. 2005-01-18T00:00:00 0 205 Medical Devices Micrus Endovascular Corporation a manufacturer of implantable and disposable medical devices used in the treatment of cerebral vascular diseases. VascularFX privately-held developer of catheters and guidewires for the interventional neurology, interventional cardiology and interventional radiology markets. Expands Micrus's neuro endovascular product line to include steerable catheters and guidewires for treatment of brain aneurisms. Deal price $4 million cash and milestone payments. 2005-07-28T00:00:00 0 206 Medical Devices Miltex Inc. a supplier of hand-held surgical and dental instruments. MeisterHand Gmbh a German manufacturer of instruments. Expands Miltex’s product line to include over 780 instrument patterns for use in the operating room, surgical center and general practice. Line is priced under Miltex’s. 2005-02-03T00:00:00 0 207 Medical Devices Nexa Orthopedics a Healthpoint Capital portfolio company focused on developing products for surgery of the extremities. Pioneer Surgical, Inc. a provider and distributor of surgical and medical specialty products (orthopedic devices) to hospitals and private practices throughout the United States. Acquisition of the trademarked StayFuse product line, a novel product used to fuse the interphalangel of the foot and hand. Expands Nexa's current product by offering surgeons an alternative approach to fusion. Terms not disclosed. 2005-07-12T00:00:00 0 208 Medical Devices Nordic Capital a Swedish private equity firm. Atos Medical AB, (a subsidiary of Fisher Scientific International) a manufacturer of ear, nose and throat medical devices. A platform growth strategy, organically and by acquisition. Transaction Value about $300 million. 2005-04-05T00:00:00 0 209 Medical Devices NuVasive, Inc.(NASDAQ:NUVA) a developer of products for minimally disruptive surgical treatments for the spine. Cervical replacement Technology from Pearsalls Limited a U.K.-based medical device company privately owned by AMI Holdings, Inc., a platform company of RoundTable Healthcare Partners. Offers NuVasive a market-first cervical nucleus-like device designed to preserve motion in the cervical region of the spine and fill the gap between pre-surgical treatment and total disc replacement or spine fusion. Transaction valued at $12 million in cash and stock, with milestone payments that could total $31.5 million (relating to FDA approval). 2005-08-04T00:00:00 0 210 Medical Devices Omni Life Science, Inc. an orthopedic products manufacturer. Apex Surgical, LLC a privately owned manufacturer of joint replacement products. Accelerates Omni's presence in joint reconstruction. Terms not disclosed. 2005-11-30T00:00:00 0 211 Medical Devices Omron Corporation a leading Japanese manufacturer of blood pressure monitors, digital thermometers and nebulizers. Colin Medical Technology a manufacturer of patient monitors, blood-pressure monitors, and vascular-profiling devices. Omron obtains bio-information monitors, vascular screening devices and other synergistic products. Enables Omron to establish new markets for preventative health information systems linking the home and medical office. Colin being sold by The Carlyle Group, which purchased it in late 2003 out of reorganization proceedings. See "Deals in the Spotlight" for details. 2005-05-13T00:00:00 0 191 Medical Devices Invacare Corporation (NYSE:IVC) a leading manufacturer and distributor of home and long-term care medical products. Australian Healthcare Company Pty Ltd. a manufacturer of beds, related furniture and pressure care products for home care market. Expands Invacare’s existing product offerings and market presence in the Australian market. 2005-01-18T00:00:00 0 202 Medical Devices Medtronic, Inc. (MDT) a major manufacturer of cardiovascular and other devices. Transneuronix, Inc. a medical device company making an implantable device for controlling obesity Strengthens Medtronic's new business unit "Medtronic Obesity Management ". Transaction price: $260 million plus contingent payments. 2005-06-29T00:00:00 0